Eag1 potassium channels as markers of cervical dysplasia

Oncology Reports

Volumn 26, Issue 6, 2011, Pages 1377-1383

  Ortiz, Cindy Sharon ^a,b   Montante Montes, Daniel ^b   Saqui Salces, Milena ^b   Hinojosa, Luz María ^c   Gamboa Dominguez, Armando ^b   Hernández Gallegos, Elisabeth ^a   Martínez Benítez, Braulio ^b   Solís Pancoatl, María Del Rosario ^a   Garcia Villa, Enrique ^a   Ramírez, Ana ^a   Aguilar Guadarrama, Ricardo ^b   Gariglio, Patricio ^a   Pardo, Luis A ^d   Stühmer, Walter ^d   Camacho, Javier ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^c HOSPITAL GENERAL DR MANUEL GEA GONZÁLEZ   (Mexico)

^d MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Cervical cancer; Estrogens; Human ether go go 1; Potassium channels; Tumor markers

Indexed keywords

POTASSIUM CHANNEL HERG;

ARTICLE; CANCER CELL CULTURE; CANCER MORTALITY; CANCER RISK; CANCER SCREENING; CANCER STAGING; CONTROLLED STUDY; DISEASE ASSOCIATION; EARLY DIAGNOSIS; ESTROGEN THERAPY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RISK REDUCTION; UTERINE CERVIX BIOPSY; UTERINE CERVIX CANCER; UTERINE CERVIX CYTOLOGY; UTERINE CERVIX DYSPLASIA;

CELL LINE, TUMOR; CERVICAL INTRAEPITHELIAL NEOPLASIA; EARLY DETECTION OF CANCER; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; GENE EXPRESSION; HUMANS; NEOPLASM GRADING; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS;

EID: 80053530300     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1441     Document Type: Article

References (26)

1. Franco EL, Duarte-Franco E and Ferenczy A: Cervical cancer: epidemiology, prevention and the role of human papilloma virus infection. CMAJ 164: 1017-1025, 2001. (Pubitemid 34412231)
2. World Health Organization (WHO). Cervical Cancer Incidence in Mexico (http://www.who.int/infobase/report.aspx?rid=119).
3. Walboomers JMM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, Snijders PJF, Peto J, Meijer CJLM and Munoz N: Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 189: 12-19, 1999. (Pubitemid 29406813)
4. Koutsky LA, Ault KA, Wheeler CM, Brown DR, Barr E, Alvarez FB, Chiacchierini LM and Jansen KU: A controlled trial of a human papillomavirus type 16 vaccine. N Engl J Med 347: 1645-1651, 2002. (Pubitemid 35340782)
5. Villa LL, Costa RLR, Petta CA, Andrade RP, Ault KA, Giuliano AR, Wheeler CM, Koutsky LA, Malm C, Lehtinen M, Skjeldestad FE, Olsson SE, Steinwall M, Brown DR, Kurman R, Ronnett BM, Stoler MH, Ferenczy A, Harper DM, Tamms GM, Yu J, Lupinacci L, Railkar R, Taddeo FJ, Jansen KU, Esser MT, Sings HL, Saah AJ and Lupinacci L: Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial. Lancet Oncol 6: 271-278, 2005. (Pubitemid 40590263)
6. Moreno V, Bosch FX, Munoz N, Meijer CJLM, Shah DV, Walboomers JMM, Herrero R and Franceschi S: Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case-control study. Lancet 359: 1085-1092, 2002. (Pubitemid 34270731)
7. Munoz N, Franceschi S, Bosetti C, Moreno V, Herrero R, Smith JS, Shah KV, Meijer CJLM and Bosch FX: Role of parity and human papillomavirus in cervical cancer: the IARC multicentric case-control study. Lancet 359: 1093-1110, 2002.
8. Jordan VC: Selective estrogen receptor modulation: concept and consequences in cancer. Cancer Cell 5: 207-213, 2004.
9. Weinberg OK, Marquez-Garban DC, Fishbein M, Goodglick L, Garban HJ, Dubinett SM and Pietras RJ: Aromatase inhibitors in human lung cancer therapy. Cancer Res 65: 11287-11291, 2005. (Pubitemid 41821684)
10. Nair HB, Luthra R, Kirma N, Liu YG, Flowers L, Evans D and Tekmal RR: Induction of aromatase expression in cervical carcinomas: effects of endogenous estrogen on cervical cancer cell proliferation. Cancer Res 65: 11164-11173, 2005. (Pubitemid 41713388)
11. Solomon D and Nayar R: The Bethesda System for Reporting Cervical cytology. Springer-Verlag, New York, 2004.
12. +channels. EMBO J 18: 5540-5547, 1999.
13. Occhiodoro TL, Bernheim L, Liu JH, Bijlenga P, Sinnreich M, Bader CR and Fischer-Lougheed J: Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion. FEBS Lett 434: 177-182, 1998. (Pubitemid 28404684)
14. Hemmerlein B, Weseloh RM, DeQueiroz FM, Knötgen H, Sánchez A, Rubio ME, Martin S, Schliephacke T, Jenke M, Heinz-Joachim-Radzun, Stühmer W and Pardo LA: Overexpression of Eag1 potassium channels in clinical tumours. Mol Cancer 5: 41, 2006.
15. Farias LMB, Ocaña DB, Díaz L, Larrea F, Avila-Chávez E, Cadena A, Hinojosa LM, Lara G, Villanueva LA, Vargas C, Hernández- Gallegos E, Camacho-Arroyo I, Dueñas-González A, Pérez-Cárdenas E, Pardo LA, Morales A, Taja-Chayeb L, Escamilla J, Sánchez-Peña C and Camacho J: Ether à go-go potassium channels as human cervical cancer markers. Cancer Res 64: 6996-7001, 2004. (Pubitemid 39331009)
16. Ousingsawat J, Spitzner M, Puntheeranurak S, Terraciano L, Tornillo L, Bubendorf L, Kunzelmann K and Schreiber R: Expression of voltage-gated potassium channels in human and mouse colonic carcinoma. Clin Cancer Res 13: 824-831, 2007. (Pubitemid 46340355)
17. DeQueiroz FM, Suarez-Kurtz G, Stühmer W and Pardo LA: Ether à go-go potassium channel expression in soft tissue sarcoma patients. Mol Cancer 5: 42, 2006.
18. Agarwal JR, Griesinger F, Stuhmer W and Pardo LA: The potassium channel ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia. Mol Cancer 9: 18, 2010.
19. + channels support proliferation of colonic carcinoma cells. FASEB J 21: 35-44, 2007.
20. Gavrilova-Ruch O, Schönherr K, Gessner G, Schönherr R, Klapperstuck T, Wohlrab W and Heinemann SH: Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells. J Membr Biol 188: 137-149, 2002. (Pubitemid 34804258)
21. Downie BR, Sánchez A, Knötgen H, Contreras-Jurado C, Gymnopoulos M, Weber C, Stühmer W and Pardo LA: Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors. J Biol Chem 238: 36234-36240, 2009.
22. Gómez-Varela D, Zwick-Wallasch E, Knötgen H, Sánchez A, Hettmann T, Ossipov D, Weseloh R, Contreras-Jurado C, Rothe M, Stühmer W and Pardo LA: Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity. Cancer Res 67: 7343-7349, 2007. (Pubitemid 47206564)
23. Díaz L, Ceja-Ochoa I, Restrepo-Angulo I, Larrea F, Avila-Chávez E, García-Becerra R, Borja-Cacho E, Barrera D, Ahumada E, Gariglio P, Alvarez-Rios E, Ocadiz-Delgado R, Garcia-Villa E, Hernandez-Gallegos E, Camacho-Arroyo I, Morales A, Ordaz-Rosado D, Garcia-Latorre E, Escamilla J, Sanchez-Pena LC, Saqui-Salces M, Gamboa-Dominguez A, Vera E, Uribe-Ramirez M, Murbartian J, Ortiz CS, Rivera-Guevara C, De Vizcaya-Ruiz A and Camacho J: Estrogens and human papilloma virus oncogenes regulate Eag1 potassium channel expression. Cancer Res 69: 3300-3307, 2009.
24. Chan YH: Biostatistics 103: qualitative data - tests of independence. Singapore Med J 44: 498-503, 2003.
25. Martin S, DeOliveira CL, DeQueiroz FM, Pardo LA, Stühmer W and Del Bel E: Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain. Neuroscience 155: 833-844, 2008.
26. Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L and Doltmesch R: The C terminus of the L-type voltage-gated calcium channel Cav1.2 encodes a transcription factor. Cell 127: 591-606, 2006. (Pubitemid 44647432)