Migration of transformed renal epithelial cells is regulated by K+ channel modulation of actin cytoskeleton and cell volume

Pflugers Archiv European Journal of Physiology

Volumn 438, Issue 3, 1999, Pages 330-337

  Schwab, Albrecht ^a   Schuricht, Barbara ^a   Seeger, Ponke ^a   Reinhardt, Jürgen ^b   Dartsch, Peter C ^c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

1 Ethyl 2 benzimidazolone (1 EBIO); Ca2+ (i); Ca2+ sensitive K+ channel; Charybdotoxin

Indexed keywords

ACTIN; BENZIMIDAZOLE DERIVATIVE; CALCIUM ION; CHARYBDOTOXIN; CYTOCHALASIN D; FURA 2 ACETOXYMETHYL ESTER; PHALLOIDIN; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM CHLORIDE;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL MIGRATION; CELL SWELLING; CELL TRANSFORMATION; CELL VOLUME; CONTROLLED STUDY; CYTOSKELETON; DEPOLYMERIZATION; EPITHELIUM CELL; KIDNEY EPITHELIUM; NONHUMAN; PRIORITY JOURNAL;

ACTINS; ANIMALS; BENZIMIDAZOLES; CALCIUM; CALCIUM CHANNEL AGONISTS; CELL LINE; CELL MOVEMENT; CELL SIZE; CHARYBDOTOXIN; CYTOSKELETON; DOGS; EPITHELIAL CELLS; FURA-2; KIDNEY; OSMOLAR CONCENTRATION; PHALLOIDINE; POTASSIUM CHANNELS; SODIUM CHLORIDE;

EID: 0032788491     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050917     Document Type: Article

References (36)

1. Condeelis J (1993) Life at the leading edge: the formation of cell protrusions. Annu Rev Cell Biol 9:411-444
2. + loss during migration of transformed Madin-Darby canine kidney cells. Pflügers Arch 433:71-76
3. + channel. Am J Physiol 271:L775-L784
4. Dieckmann-Schuppert A, Schnittler H-J (1997) A simple assay for quantification of protein in tissue sections, cell cultures, cell homogenates and of protein immobilized on solid surfaces. Cell Tissue Res 288:119-126
5. Downey GP, Chan CK, Trudel S, Grinstein S (1990) Actin assembly in electropermeabilized neutrophils: role of intracellular calcium. J Cell Biol 110: 1975-1982
6. Ehrengruber MU, Deranleau DA, Coates TD (1996) Shape oscillations of human neutrophil leukocytes: characterization and relationship to cell motility. J Exp Biol 199:741-747
7. Gallin EK (1989) Evidence for a Ca-activated rectifying K channel in human macrophages. Am J Physiol 257:C77-C85
8. + antiport: assessment of effects on intracellular pH. EMBO J 12:5209-5218
9. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
10. Guilford WH, Lantz RC, Gore RW (1995) Locomotive forces produced by single leukocytes in vivo and in vitro. Am J Physiol 268:C1308-C1312
11. Hallows KR, Packman CH, Knauf PA (1991) Acute cell volume changes in anisotonic media affect F-actin content of HL-60 cells. Am J Physiol 261:C1154-C1161
12. Ishii TM, Silvia C, Hirschberg B, Bond CT, Adelman JP, Maylie J (1997) A human intermediate conductance calcium-activated potassium channel. Proc Natl Acad Sci USA 94:11651-11656
13. Janmey PA (1994) Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly. Annu Rev Physiol 56:169-191
14. + channel. Am J Physiol 275:C848-C856
15. Kater SB, Mills LR (1991) Regulation of growth cone behavior by calcium. J Neurosci 11:981-899
16. 3 in fused renal epitheloid (MDCK) cells. Kidney Int 39:891-900
17. Lang F, Busch GL, Ritter M, Völkl H, Waldegger S, Gulbins E, Häussinger D (1998) Functional significance of cell volume regulatory mechanisms. Physiol Rev 78:247-306
18. Lauffenburger DA, Horwitz AF (1996) Cell migration: a physically integrated molecular process. Cell 84:359-369
19. 2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature 376:75-79
20. Mitchison TJ, Cramer LP (1996) Actin-based cell motility and cell locomotion. Cell 84:371-379
21. Oberleithner H, Westphale H-J, Gassner B (1991) Alkaline stress transforms Madin-Darby canine kidney cells. Pflügers Arch 419:418-420
22. Oster GF, Perelson AS (1987) The physics of cell motility. J Cell Sci Suppl 8:35-54
23. Palecek SP, Loftus JC, Ginsberg MH, Lauffenburger DA, Horwitz AF (1997) Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature 385:537-540
24. Schneider SW, Oberleithner H, Schillers H, Schwab A (1998) Volume dynamics in migrating epithelial cells imaged with atomic force microscopy (abstract). Pflügers Arch 435:R61
25. 2+ distribution in migrating transformed renal epithelial cells. Pflügers Arch 434:70-76
26. Schwab A, Oberleithner H (1996). Plasticity of renal epithelial cells: the way a potassium channel supports migration. Pflügers Arch 432:R87-R93
27. + channel activity in transformed Madin-Darby canine kidney cells. J Clin Invest 92:218-223
28. + channel - a prerequisite for migration of alkali-transformed Madin-Darby canine kidney (MDCK-F) cells. J Clin Invest 93:1631-1636
29. Schwab A, Gabriel K, Finsterwalder F, Folprecht G, Greger R, Kramer A, Oberleithner H (1995) Polarized ion transport during migration of transformed Madin-Darby canine kidney cells. Pflügers Arch 430:802-807
30. + channel dependent migration of fibroblasts and human melanoma cells. Cell Physiol Biochem (in press)
31. - exchangers in migrating renal cells (abstract). J Am Soc Nephrol 8:63A
32. 2+ entry pathway. Pflügers Arch 429:663-671
33. 3 followed by sustained KCl accumulation. Pflügers Arch 419:43-50
34. 2+ oscillator in Madin-Darby canine kidney cells. Pflügers Arch 426:89-94
35. Wöll E, Ritter M, Haller T, Völkl H, Lang F (1996) Calcium entry stimulated by swelling of Madin-Darby canine kidney cells. Nephron 74:150-157
36. Wymann MP, Kernen P, Bengtsson T, Andersson T, Bagglioni M, Deranleau DA (1990) Corresponding oscillations in neutrophil shape and filamentous actin content. J Biol Chem 265:619-622