Sphingosine 1-phosphate and human ether-a′-go-go-related gene potassium channels modulate migration in human anaplastic thyroid cancer cells

Endocrine-Related Cancer

Volumn 19, Issue 5, 2012, Pages 667-680

  Asghar, Muhammad Yasir ^a   Viitanen, Tero ^b,c   Kemppainen, Kati ^a   Törnquist, Kid ^a,b  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL HERG; RAC PROTEIN; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

ANAPLASTIC THYROID CANCER; ARTICLE; ATTENUATION; CANCER CELL; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ETHER-A-GO-GO POTASSIUM CHANNELS; HEK293 CELLS; HUMANS; LYSOPHOSPHOLIPIDS; RECEPTORS, LYSOSPHINGOLIPID; RNA, MESSENGER; SPHINGOSINE; THYROID NEOPLASMS;

EID: 84867427541     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-12-0092     Document Type: Article

References (36)

1. Afrasiabi E, Hietamaki M, Viitanen T, Sukumaran P, Bergelin N & Tornquist K 2010 Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration. Cellular Signalling 22 57-64. (doi:10.1016/j.cellsig.2009.09.010)
2. Arcangeli A 2005 Expression and role of hERG channels in cancer cells. Novartis Foundation Symposium 266 225-234.
3. + current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells. Journal of Physiology 489 455-471.
4. Balthasar S, Samulin J, Ahlgren H, Bergelin N, Lundqvist M, Toescu EC, Eggo MC & Tornquist K 2006 Sphingosine 1-phosphate receptor expression profile and regulation of migration in human thyroid cancer cells. Biochemical Journal 398 547-556. (doi:10.1042/BJ20060299)
5. Barry PH 1994 JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements. Journal of Neuroscience Methods 51 107-116. (doi:10.1016/0165-0270(94)90031-0)
6. Bergelin N, Blom T, Heikkila J, Lof C, Alam C, Balthasar S, Slotte JP, Hinkkanen A & Tornquist K 2009 Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on protein kinase C-α and ERK1/2. Endocrinology 150 2055-2063. (doi:10.1210/en.2008-0625)
7. + current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells? Cancer Research 58 815-822.
8. + channel by ceramide: evidence for ubiquitin-mediated lysosomal degradation. Journal of Cell Science 118 5325-5334. (doi:10.1242/jcs.02635)
9. Gault CR & Obeid LM 2011 Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy. Critical Reviews in Biochemistry and Molecular Biology 46 342-351. (doi:10.3109/10409238. 2011.597737)
10. Gonda K, Okamoto H, Takuwa N, Yatomi Y, Okazaki H, Sakurai T, Kimura S, Sillard R, Harii K & Takuwa Y 1999 The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways. Biochemical Journal 337 67-75. (doi:10.1042/0264-6021:3370067)
11. Guan H, Liu L, Cai J, Liu J, Ye C, Li M & Li Y 2011 Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer. Molecular Endocrinology 25 1858-1866. (doi:10.1210/me.2011-1048)
12. Hamill OP, Marty A, Neher E, Sakmann B & Sigworth FJ 1981 Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Archiv 391 85-100. (doi:10.1007/BF00656997)
13. Hashimoto M, Wang X, Mao L, Kobayashi T, Kawasaki S, Mori N, Toews ML, Kim HJ, Cerutis DR, Liu X et al. 2008 Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptor. American Journal of Respiratory Cell and Molecular Biology 39 356-363. (doi:10.1165/rcmb.2006- 0427OC)
14. + channels. PNAS 103 2886-2891. (doi:10.1073/pnas.0505909103)
15. Ishii I, Ye X, Friedman B, Kawamura S, Contos JJ, Kingsbury MA, Yang AH, Zhang G, Brown JH & Chun J 2002 Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3. Journal of Biological Chemistry 277 25152-25159. (doi:10.1074/jbc.M200137200)
16. Ishii I, Fukushima N, Ye X & Chun J 2004 Lysophospholipid receptors: signaling and biology. Annual Review of Biochemistry 73 321-354. (doi:10.1146/annurev.biochem.73.011303.073731)
17. Kaczmarek LK 2006 Non-conducting functions of voltage-gated ion channels. Nature Reviews. Neuroscience 7 761-771. (doi:10.1038/nrn1988)
18. Keely PJ, Westwick JK, Whitehead IP, Der CJ & Parise LV 1997 Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature 390 632-636. (doi:10.1038/37656)
19. Lepley D, Paik JH, Hla T & Ferrer F 2005 The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration. Cancer Research 65 3788-3795. (doi:10.1158/0008-5472.CAN-04-2311)
20. Marlow LA, D'Innocenzi J, Zhang Y, Rohl SD, Cooper SJ, Sebo T, Grant C, McIver B, Kasperbauer JL, Wadsworth JT et al. 2010 Detailed molecular fingerprinting of four new anaplastic thyroid carcinoma cell lines and their use for verification of RhoB as a molecular therapeutic target. Journal of Clinical Endocrinology and Metabolism 95 5338-5347. (doi:10.1210/jc.2010-1421)
21. Nagaiah G, Hossain A, Mooney CJ, Parmentier J&Remick SC 2011 Anaplastic thyroid cancer: a review of epidemiology, pathogenesis, and treatment. Journal of Oncology 2011 article ID 542358. (doi:10.1155/2011/542358)
22. Okamoto H, Takuwa N, Yokomizo T, Sugimoto N, Sakurada S, Shigematsu H & Takuwa Y 2000 Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3. Molecular and Cellular Biology 20 9247-9261. (doi:10.1128/MCB.20.24.9247-9261.2000)
23. Prevarskaya N, Skryma R & Shuba Y 2010 Ion channels and the hallmarks of cancer. Trends in Molecular Medicine 16 107-121. (doi:10.1016/j.molmed.2010. 01.005)
24. Ramstrom C, Chapman H, Viitanen T, Afrasiabi E, Fox H, Kivela J, Soini S, Korhonen L, Lindholm D, Pasternack M et al. 2010 Regulation of HERG (KCNH2) potassium channel surface expression by diacylglycerol. Cellular and Molecular Life Sciences 67 157-169. (doi:10.1007/s00018-009-0176-2)
25. Sanchez T, Thangada S, Wu MT, Kontos CD, Wu D, Wu H & Hla T 2005 PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. PNAS 102 4312-4317. (doi:10.1073/pnas.0409784102)
26. Sanguinetti MC, Jiang C, Curran ME & Keating MT 1995 A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81 299-307. (doi:10.1016/0092-8674(95)90340-2)
27. Schweppe RE, Klopper JP, Korch C, Pugazhenthi U, Benezra M, Knauf JA, Fagin JA, Marlow LA, Copland JA, Smallridge RC et al. 2008 Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. Journal of Clinical Endocrinology and Metabolism 93 4331-4341. (doi:10.1210/jc.2008-1102)
28. Smallridge RC, Marlow LA & Copland JA 2009 Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies. Endocrine-Related Cancer 16 17-44. (doi:10.1677/ERC-08-0154)
29. Smith PL, Baukrowitz T & Yellen G 1996 The inward rectification mechanism of the HERG cardiac potassium channel. Nature 379 833-836. (doi:10.1038/379833a0)
30. Spiegel S, English D & Milstien S 2002 Sphingosine 1-phosphate signaling: providing cells with a sense of direction. Trends in Cell Biology 12 236-242. (doi:10.1016/S0962-8924(02)02277-8)
31. Storey NM, O'Bryan JP & Armstrong DL 2002 Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel. Current Biology 12 27-33. (doi:10.1016/S0960-9822(01)00625-X)
32. Takabe K, Paugh SW, Milsien S & Spiegel S 2008 "Inside- out"signaling of sphingosine-1-ohosphate: therapeutic targets. Pharmacological Reviews 60 181-195. (doi:10.1124/pr.107.07113)
33. Takashima S, Sugimoto N, Takuwa N, Okamoto Y, Yoshioka K, Takamura M, Takata S, Kaneko S&Takuwa Y 2008 G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smoothmuscle in a manner dependent on Rho but not Rho kinase. Cardiovascular Research 79 689-697. (doi:10.1093/cvr/cvn118)
34. Takuwa N, Du W, Kaneko E, Okamoto Y, Yoshioka K &Takuwa Y 2011 Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind Hyde. American Journal of Cancer Research 1 460-481.
35. Windh RT, Lee MJ, Hla T, An S, Barr AJ & Manning DR 1999 Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins. Journal of Biological Chemistry 274 27351-27358. (doi:10.1074/jbc.274.39.27351)
36. Witt W, Jannasch A, Burkhard D, Christ T, Ravens U, Brunssen C, Leuner A, Morawietz H, Matschke K &Waldow T 2012 Sphingosine-1-phosphate induces contraction of valvular interstitial cells from porcine aortic valves. Cardiovascular Research 93 490-497. (doi:10.1093/cvr/cvs002)