메뉴 건너뛰기




Volumn 110, Issue 51, 2013, Pages 20819-20824

Stoichiometry for activation of neuronal α7 nicotinic receptors

Author keywords

7 nicotinic receptor; Agonist binding site; Channel gating; Cys loop receptors; Patch clamp

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINE NICOTINIC RECEPTOR ALPHA7; ION CHANNEL; NEUROTRANSMITTER; NICOTINIC RECEPTOR; SEROTONIN 3A RECEPTOR; UNCLASSIFIED DRUG;

EID: 84890810573     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315775110     Document Type: Article
Times cited : (81)

References (37)
  • 1
    • 58049091080 scopus 로고    scopus 로고
    • Diversity of vertebrate nicotinic acetylcholine receptors
    • Millar NS, Gotti C (2009) Diversity of vertebrate nicotinic acetylcholine receptors. Neuropharmacology 56(1):237-246.
    • (2009) Neuropharmacology , vol.56 , Issue.1 , pp. 237-246
    • Millar, N.S.1    Gotti, C.2
  • 2
    • 33847029091 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
    • Dani JA, Bertrand D (2007) Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annu Rev Pharmacol Toxicol 47:699-729.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 699-729
    • Dani, J.A.1    Bertrand, D.2
  • 3
    • 77949462775 scopus 로고    scopus 로고
    • Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: From animal models to human pathophysiology
    • Thomsen MS, Hansen HH, Timmerman DB, Mikkelsen JD (2010) Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: From animal models to human pathophysiology. Curr Pharm Des 16(3):323-343.
    • (2010) Curr Pharm des , vol.16 , Issue.3 , pp. 323-343
    • Thomsen, M.S.1    Hansen, H.H.2    Timmerman, D.B.3    Mikkelsen, J.D.4
  • 4
    • 80052028010 scopus 로고    scopus 로고
    • Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease
    • Wallace TL, Porter RH (2011) Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease. Biochem Pharmacol 82(8):891-903.
    • (2011) Biochem Pharmacol , vol.82 , Issue.8 , pp. 891-903
    • Wallace, T.L.1    Porter, R.H.2
  • 5
    • 84872295116 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors: From basic science to therapeutics
    • Hurst R, Rollema H, Bertrand D (2013) Nicotinic acetylcholine receptors: From basic science to therapeutics. Pharmacol Ther 137(1):22-54.
    • (2013) Pharmacol Ther , vol.137 , Issue.1 , pp. 22-54
    • Hurst, R.1    Rollema, H.2    Bertrand, D.3
  • 6
    • 84872234860 scopus 로고    scopus 로고
    • Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia
    • Wallace TL, Bertrand D (2013) Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia. Expert Opin Ther Targets 17(2):139-155.
    • (2013) Expert Opin Ther Targets , vol.17 , Issue.2 , pp. 139-155
    • Wallace, T.L.1    Bertrand, D.2
  • 7
    • 77949422530 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptors: Targets for the development of drugs to treat cognitive impairment associated with schizophrenia and Alzheimer's disease
    • Haydar SN, Dunlop J (2010) Neuronal nicotinic acetylcholine receptors: Targets for the development of drugs to treat cognitive impairment associated with schizophrenia and Alzheimer's disease. Curr Top Med Chem 10(2):144-152.
    • (2010) Curr Top Med Chem , vol.10 , Issue.2 , pp. 144-152
    • Haydar, S.N.1    Dunlop, J.2
  • 8
    • 84857663983 scopus 로고    scopus 로고
    • Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology
    • Pohanka M (2012) Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology. Int J Mol Sci 13(2):2219-2238.
    • (2012) Int J Mol Sci , vol.13 , Issue.2 , pp. 2219-2238
    • Pohanka, M.1
  • 9
    • 84861189283 scopus 로고    scopus 로고
    • New insights into the structural bases of activation of Cys-Loop receptors
    • Bouzat C (2012) New insights into the structural bases of activation of Cys-Loop receptors. J Physiol Paris 106(1-2):23-33.
    • (2012) J Physiol Paris , vol.106 , Issue.1-2 , pp. 23-33
    • Bouzat, C.1
  • 10
    • 84861963413 scopus 로고    scopus 로고
    • Structure and pharmacology of pentameric receptor channels: From bacteria to brain
    • Corringer PJ, et al. (2012) Structure and pharmacology of pentameric receptor channels: From bacteria to brain. Structure 20(6):941-956.
    • (2012) Structure , vol.20 , Issue.6 , pp. 941-956
    • Corringer, P.J.1
  • 11
    • 84864060207 scopus 로고    scopus 로고
    • End-Plate acetylcholine receptor: Structure, mechanism, pharmacology, and disease
    • Sine SM (2012) End-Plate acetylcholine receptor: Structure, mechanism, pharmacology, and disease. Physiol Rev 92(3):1189-1234.
    • (2012) Physiol Rev , vol.92 , Issue.3 , pp. 1189-1234
    • Sine, S.M.1
  • 12
    • 0034602138 scopus 로고    scopus 로고
    • Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons
    • Mike A, Castro NG, Albuquerque EX (2000) Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons. Brain Res 882(1-2):155-168.
    • (2000) Brain Res , vol.882 , Issue.1-2 , pp. 155-168
    • Mike, A.1    Castro, N.G.2    Albuquerque, E.X.3
  • 13
    • 50349093448 scopus 로고    scopus 로고
    • The interface between extracellular and transmembrane domains of homomeric Cys-Loop receptors governs open-Channel lifetime and rate of desensitization
    • Bouzat C, Bartos M, Corradi J, Sine SM (2008) The interface between extracellular and transmembrane domains of homomeric Cys-Loop receptors governs open-Channel lifetime and rate of desensitization. J Neurosci 28(31):7808-7819.
    • (2008) J Neurosci , vol.28 , Issue.31 , pp. 7808-7819
    • Bouzat, C.1    Bartos, M.2    Corradi, J.3    Sine, S.M.4
  • 14
    • 42049100322 scopus 로고    scopus 로고
    • Nonsynaptic chemical transmission through nicotinic acetylcholine receptors
    • Lendvai B, Vizi ES (2008) Nonsynaptic chemical transmission through nicotinic acetylcholine receptors. Physiol Rev 88(2):333-349.
    • (2008) Physiol Rev , vol.88 , Issue.2 , pp. 333-349
    • Lendvai, B.1    Vizi, E.S.2
  • 15
    • 69349105057 scopus 로고    scopus 로고
    • Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation
    • De Rosa MJ, Dionisio L, Agriello E, Bouzat C, Esandi MdelC (2009) Alpha 7 nicotinic acetylcholine receptor modulates lymphocyte activation. Life Sci 85(11-12):444-449.
    • (2009) Life Sci , vol.85 , Issue.11-12 , pp. 444-449
    • De Rosa, M.J.1    Dionisio, L.2    Agriello, E.3    Bouzat, C.4    Esandi, M.5    Del, C.6
  • 16
    • 84859398826 scopus 로고    scopus 로고
    • Reflex principles of immunological homeostasis
    • Andersson U, Tracey KJ (2012) Reflex principles of immunological homeostasis. Annu Rev Immunol 30:313-335.
    • (2012) Annu Rev Immunol , vol.30 , pp. 313-335
    • Andersson, U.1    Tracey, K.J.2
  • 17
    • 84862696408 scopus 로고    scopus 로고
    • Sperm epidermal growth factor receptor (EGFR) mediates á7 acetylcholine receptor (AChR) activation to promote fertilization
    • Jaldety Y, et al. (2012) Sperm epidermal growth factor receptor (EGFR) mediates á7 acetylcholine receptor (AChR) activation to promote fertilization. J Biol Chem 287(26): 22328-22340.
    • (2012) J Biol Chem , vol.287 , Issue.26 , pp. 22328-22340
    • Jaldety, Y.1
  • 18
    • 65949085351 scopus 로고    scopus 로고
    • Number and locations of agonist binding sites required to activate homomeric Cys-Loop receptors
    • Rayes D, De Rosa MJ, Sine SM, Bouzat C (2009) Number and locations of agonist binding sites required to activate homomeric Cys-Loop receptors. J Neurosci 29(18): 6022-6032.
    • (2009) J Neurosci , vol.29 , Issue.18 , pp. 6022-6032
    • Rayes, D.1    De Rosa, M.J.2    Sine, S.M.3    Bouzat, C.4
  • 19
    • 79955645582 scopus 로고    scopus 로고
    • The effective opening of nicotinic acetylcholine receptors with single agonist binding sites
    • Williams DK, Stokes C, Horenstein NA, Papke RL (2011) The effective opening of nicotinic acetylcholine receptors with single agonist binding sites. J Gen Physiol 137(4):369-384.
    • (2011) J Gen Physiol , vol.137 , Issue.4 , pp. 369-384
    • Williams, D.K.1    Stokes, C.2    Horenstein, N.A.3    Papke, R.L.4
  • 20
    • 79952394893 scopus 로고    scopus 로고
    • Functional relationships between agonist binding sites and coupling regions of homomeric Cys-Loop receptors
    • Andersen N, Corradi J, Bartos M, Sine SM, Bouzat C (2011) Functional relationships between agonist binding sites and coupling regions of homomeric Cys-Loop receptors. J Neurosci 31(10):3662-3669.
    • (2011) J Neurosci , vol.31 , Issue.10 , pp. 3662-3669
    • Andersen, N.1    Corradi, J.2    Bartos, M.3    Sine, S.M.4    Bouzat, C.5
  • 21
    • 84876208084 scopus 로고    scopus 로고
    • Stoichiometry for drug potentiation of a pentameric ion channel
    • DaCosta CJ, Sine SM (2013) Stoichiometry for drug potentiation of a pentameric ion channel. Proc Natl Acad Sci USA 110(16):6595-6600.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.16 , pp. 6595-6600
    • Dacosta, C.J.1    Sine, S.M.2
  • 22
    • 80053244433 scopus 로고    scopus 로고
    • Single-Channel and structural foundations of neuronal á7 acetylcholine receptor potentiation
    • DaCosta CJ, Free CR, Corradi J, Bouzat C, Sine SM (2011) Single-Channel and structural foundations of neuronal á7 acetylcholine receptor potentiation. J Neurosci 31(39): 13870-13879.
    • (2011) J Neurosci , vol.31 , Issue.39 , pp. 13870-13879
    • Dacosta, C.J.1    Free, C.R.2    Corradi, J.3    Bouzat, C.4    Sine, S.M.5
  • 23
    • 0036711318 scopus 로고    scopus 로고
    • 5-Hydroxyindole potentiates human alpha 7 nicotinic receptormediated responses and enhances acetylcholine-Induced glutamate release in cerebellar slices
    • Zwart R, et al. (2002) 5-Hydroxyindole potentiates human alpha 7 nicotinic receptormediated responses and enhances acetylcholine-Induced glutamate release in cerebellar slices. Neuropharmacology 43(3):374-384.
    • (2002) Neuropharmacology , vol.43 , Issue.3 , pp. 374-384
    • Zwart, R.1
  • 24
    • 34548301101 scopus 로고    scopus 로고
    • Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes
    • Grønlien JH, et al. (2007) Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes. Mol Pharmacol 72(3):715-724.
    • (2007) Mol Pharmacol , vol.72 , Issue.3 , pp. 715-724
    • Grønlien, J.H.1
  • 25
    • 70349584397 scopus 로고    scopus 로고
    • Single-Channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors
    • Corradi J, Gumilar F, Bouzat C (2009) Single-Channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors. Biophys J 97(5):1335-1345.
    • (2009) Biophys J , vol.97 , Issue.5 , pp. 1335-1345
    • Corradi, J.1    Gumilar, F.2    Bouzat, C.3
  • 26
    • 0041806486 scopus 로고    scopus 로고
    • A cytoplasmic region determines single-Channel conductance in 5-HT3 receptors
    • Kelley SP, Dunlop JI, Kirkness EF, Lambert JJ, Peters JA (2003) A cytoplasmic region determines single-Channel conductance in 5-HT3 receptors. Nature 424(6946): 321-324.
    • (2003) Nature , vol.424 , Issue.6946 , pp. 321-324
    • Kelley, S.P.1    Dunlop, J.I.2    Kirkness, E.F.3    Lambert, J.J.4    Peters, J.A.5
  • 27
    • 4344616080 scopus 로고    scopus 로고
    • Coupling of agonist binding to channel gating in an AChbinding protein linked to an ion channel
    • Bouzat C, et al. (2004) Coupling of agonist binding to channel gating in an AChbinding protein linked to an ion channel. Nature 430(7002):896-900.
    • (2004) Nature , vol.430 , Issue.7002 , pp. 896-900
    • Bouzat, C.1
  • 28
    • 27544485478 scopus 로고    scopus 로고
    • Single-Channel kinetic analysis of chimeric alpha7-5HT3A receptors
    • Rayes D, Spitzmaul G, Sine SM, Bouzat C (2005) Single-Channel kinetic analysis of chimeric alpha7-5HT3A receptors. Mol Pharmacol 68(5):1475-1483.
    • (2005) Mol Pharmacol , vol.68 , Issue.5 , pp. 1475-1483
    • Rayes, D.1    Spitzmaul, G.2    Sine, S.M.3    Bouzat, C.4
  • 29
    • 80052026910 scopus 로고    scopus 로고
    • Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-Targeted therapeutics: Advantages and limitations
    • Williams DK, Wang J, Papke RL (2011) Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-Targeted therapeutics: Advantages and limitations. Biochem Pharmacol 82(8):915-930.
    • (2011) Biochem Pharmacol , vol.82 , Issue.8 , pp. 915-930
    • Williams, D.K.1    Wang, J.2    Papke, R.L.3
  • 30
    • 78651189765 scopus 로고
    • On the nature of allosteric transitions: A plausible model
    • Monod J, Wyman J, Changeux JP (1965) On the nature of allosteric transitions: A plausible model. J Mol Biol 12:88-118.
    • (1965) J Mol Biol , vol.12 , pp. 88-118
    • Monod, J.1    Wyman, J.2    Changeux, J.P.3
  • 31
    • 0034059664 scopus 로고    scopus 로고
    • Nicotinic receptor fourth transmembrane domain: Hydrogen bonding by conserved threonine contributes to channel gating kinetics
    • Bouzat C, Barrantes F, Sine S (2000) Nicotinic receptor fourth transmembrane domain: Hydrogen bonding by conserved threonine contributes to channel gating kinetics. J Gen Physiol 115(5):663-672.
    • (2000) J Gen Physiol , vol.115 , Issue.5 , pp. 663-672
    • Bouzat, C.1    Barrantes, F.2    Sine, S.3
  • 32
    • 84861145025 scopus 로고    scopus 로고
    • The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel
    • Nayak TK, Purohit PG, Auerbach A (2012) The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel. J Gen Physiol 139(5):349-358.
    • (2012) J Gen Physiol , vol.139 , Issue.5 , pp. 349-358
    • Nayak, T.K.1    Purohit, P.G.2    Auerbach, A.3
  • 33
    • 84876411224 scopus 로고    scopus 로고
    • The energy and work of a ligand-Gated ion channel
    • Auerbach A (2013) The energy and work of a ligand-Gated ion channel. J Mol Biol 425(9):1461-1475.
    • (2013) J Mol Biol , vol.425 , Issue.9 , pp. 1461-1475
    • Auerbach, A.1
  • 34
    • 79960120380 scopus 로고    scopus 로고
    • Desensitization of alpha7 nicotinic receptor is governed by coupling strength relative to gate tightness
    • Zhang J, et al. (2011) Desensitization of alpha7 nicotinic receptor is governed by coupling strength relative to gate tightness. J Biol Chem 286(28):25331-25340.
    • (2011) J Biol Chem , vol.286 , Issue.28 , pp. 25331-25340
    • Zhang, J.1
  • 35
    • 84876681700 scopus 로고    scopus 로고
    • An outline of desensitization in pentameric ligandgated ion channel receptors
    • Keramidas A, Lynch JW (2013) An outline of desensitization in pentameric ligandgated ion channel receptors. Cell Mol Life Sci 70(7):1241-1253.
    • (2013) Cell Mol Life Sci , vol.70 , Issue.7 , pp. 1241-1253
    • Keramidas, A.1    Lynch, J.W.2
  • 36
    • 84880898531 scopus 로고    scopus 로고
    • The structural mechanism of the Cysloop receptor desensitization
    • Zhang J, Xue F, Liu Y, Yang H, Wang X (2013) The structural mechanism of the Cysloop receptor desensitization. Mol Neurobiol 48(1):97-108.
    • (2013) Mol Neurobiol , vol.48 , Issue.1 , pp. 97-108
    • Zhang, J.1    Xue, F.2    Liu, Y.3    Yang, H.4    Wang, X.5
  • 37
    • 0029670737 scopus 로고    scopus 로고
    • Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine
    • Palma E, Bertrand S, Binzoni T, Bertrand D (1996) Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. J Physiol 491(Pt 1):151-161.
    • (1996) J Physiol , vol.491 , Issue.PART 1 , pp. 151-161
    • Palma, E.1    Bertrand, S.2    Binzoni, T.3    Bertrand, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.