Ischaemic tolerance in aged mouse myocardium: The role of adenosine and effect of A1 adenosine receptor overexpression

Journal of Physiology

Volumn 549, Issue 3, 2003, Pages 823-833

  Headrick, John P ^b   Willems, Laura ^b   Ashton, Kevin J ^b   Holmgren, Kirsten ^b   Peart, Jason ^b   Matherne, G Paul ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYDECANOIC ACID; 8 (4 SULFOPHENYL)THEOPHYLLINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; CHELERYTHRINE; DIAZOXIDE; LACTATE DEHYDROGENASE; MESSENGER RNA; RADIOLIGAND;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; CONTROLLED STUDY; FEMALE; FUNCTIONAL ASSESSMENT; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE ENDDIASTOLIC PRESSURE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RADIOASSAY; RECEPTOR BLOCKING; RECEPTOR DENSITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; TACHYCARDIA; AGED; ARTICLE; DIASTOLIC BLOOD PRESSURE; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ADENOSINE; AGING; ALKALOIDS; ANIMALS; ARRHYTHMIA; BENZOPHENANTHRIDINES; CORONARY CIRCULATION; DECANOIC ACIDS; DIAZOXIDE; DNA PRIMERS; FEMALE; GENE EXPRESSION; HEART; HYDROXY ACIDS; L-LACTATE DEHYDROGENASE; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; ORGAN SIZE; PHENANTHRIDINES; RECEPTOR, ADENOSINE A1; VASODILATOR AGENTS;

EID: 0038380612     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.041541     Document Type: Review

References (55)

1. Abete P, Cioppa A, Calabrese C, Pascucci I, Cacciatore F, Napoli C, Carnovale V, Ferrara N & Rengo F (1999). Ischemic threshold and myocardial stunning in the aging heart. Exp Gerontol 34, 875-884.
2. Abete P, Ferrara N, Cioppa A, Ferrara P, Bianco S, Calabrese C, Cacciatore F, Longobardi G & Rengo F (1996). Preconditioning does not prevent postischemic dysfunction in aging heart. J Am Coll Cardiol 27, 1777-1786.
3. Boucher F, Tanguy S, Toufektsian MC, Besse S & De Leiris J (2000). Effects of fasting and exogenous glucose delivery on cardiac tolerance to low-flow ischemia in adult and senescent rats. Mech Ageing Dev 116, 15-32.
4. Boucher F, Tanguy S, Toufektsian MC, Besse S, Tressallet N, Favier A & De Leiris J (1998). Age-dependent changes in myocardial susceptibility to zero flow ischemia and reperfusion in isolated perfused rat hearts: relation to antioxidant status. Mech Ageing Dev 103, 301-316.
5. Bulteau AL, Szweda LI & Friguet B (2002). Age-dependent declines in proteasome activity in the heart. Arch Biochem Biophys 397, 298-304.
6. 1 receptor and Gα protein coupling in rat ventricular myocardium during aging. Circ Rcs 81, 1065-1071.
7. Cain BS, Meldrum DR, Joo KS, Wang J-F, Meng X, Cleveland JC Jr, Banerjee A & Harken AH (1998). Human SERCA2a levels correlate inversely with age in senescent human myocardium. J Am Coll Cardiol 32, 458-467.
8. ATP channels. Circ Res 89, 273-278.
9. Coombes JS, Powers SK, Hamilton KL, Demirel HA, Shanely RA, Zergeroglu MA, Sen CK, Packer L & Ji LL (2000). Improved cardiac performance after ischemia in aged rats supplemented with vitamin E and alpha-lipoic acid. Am J Physiol Reg Int Comp Physiol 279, R2149-2155.
10. Cross HR, Opie LH, Radda GK & Clarke K (1996). Is a high glycogen content beneficial or detrimental to the ischemic rat heart? A controversy resolved. Circ Res 78, 482-491.
11. 1 receptor binding sites in the rat brain - Effect of cis unsaturated free fatty acids. Eur J Biochem 268, 2939-2947.
12. Do XJ, Anderson K, Jacobsen A, Woodcock E & Dart A (1995). Suppression of ventricular arrhythmias during ischaemia-reperfusion by agents inhibiting Ins(1,4,5)P3 release. Circulation 91, 2712-2716.
13. 2+ transport in myocardium. Gerontology 37, 233-239.
14. 1 receptor function in the rat heart. J Mol Cell Cardiol 29, 593-602.
15. Gao F, Christopher TA, Lopez BL, Friedman E, Cai G & Ma XL (2000). Mechanism of decreased adenosine protection in reperfusion injury of aging rats. Am J Physiol Heart Circ Physiol 279, H329-338.
16. ATP channel as a receptor for potassium channel openers. J Biol Chem 271, 8796-8799.
17. 1 adenosine receptors in the heart. Drug Dev Res 45, 402-409.
18. ATP channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart. J Physiol 542, 735-741.
19. Headrick JP (1998). Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation. J Mol Cell Cardiol 30, 1415-1430.
20. 1 adenosine receptors. Am J Physiol Heart Circ Physiol 279, H1690-1697.
21. Headrick JP, Peart J, Hack B, Flood A & Matherne GP (2001). Functional properties and responses to ischemia reperfusion in Langendorff perfused mouse hearts. Exp Physiol 86, 703-716.
22. Kita H, Miura T, Tsuchida A, Hasegawa T & Shimamoto K (1998). Suppression of reperfusion arrhythmias by preconditioning is inhibited by an ATP-sensitive potassium channel blocker, 5-hydroxydecanoate, but not by protein kinase C blockers in the rat. J Cardiovasc Pharmacol 32, 791-797.
23. Kolocassides KG, Galinanes M & Hearse DJ (1996). Ischemic preconditioning, cardioplegia or both? Differing approaches to myocardial and vascular protection. J Mol Cell Cardiol 28, 623-634.
24. Korzick DH, Holiman DA, Boluyt MO, Laughlin MH & Lakatta EG (2001). Diminished alpha1-adrenergic-mediated contraction and translocation of PKC in senescent rat heart. Am J Physiol Heart Circ Physiol 281, H581-589.
25. Krieg T, Qin QN, McIntosh EC, Cohen MV & Downey JM (2002). ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases. Am J Physiol Heart Circ Physiol 283, H2322-2330.
26. Lee TM, Su SF, Chou TF, Lee YT & Tsai CH (2002). Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty. Circulation 105, 334-340.
27. Lesnefsky EJ, Gallo DS, Ye J, Whittingham TS & Lust WD (1994). Aging increases ischemia-reperfusion injury in the isolated, buffer-perfused heart. J Lab Clin Med 124, 843-851.
28. Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J & Hoppel CL (2001). Mitochondrial dysfunction in cardiac disease: Ischemia-reperfusion, aging, and heart failure. J Mol Cell Cardiol 33, 1065-1089.
29. 2 receptor-induced cardioprotection in guinea pig hearts. J Mol Cell Cardiol 33, 2047-2053.
30. Liu Y, Sato T, O'Rourke B & Marban E (1998). Mitochondrial ATP-dependent potassium channels:novel effectors of cardioprotection? Circulation 97, 2463-2469.
31. McCully JD, Uematsu M, Parker RA & Levitsky S (1998). Adenosine-enhanced ischemic preconditioning provides enhanced cardioprotection in the aged heart. Ann Thorac Surg 66, 2037-2043.
32. Mariani J, Ou RC, Bailey M, Rowland M, Nagley P, Rosenfeldt F & Pepe S (2000). Tolerance to ischemia and hypoxia is reduced in aged human myocardium. J Thorac Cardiovasc Surg 120, 660-667.
33. Martineau LC, Chadan SG & Parkhouse WS (1999). Age-associated alterations in cardiac and skeletal muscle glucose transporters, insulin and IGF-1 receptors, and PI3-kinase protein contents in the C57BL/6 mouse. Mech AgeingDev 106, 217-232.
34. Matherne GP, Berr SS & Headrick JP (1996). Integration of vascular, contractile and metabolic responses to hypoxia: Effects of maturation and the role of adenosine. Am J Physiol 270, R895-905.
35. 1 adenosine receptor over-expression increases myocardial resistance to ischemia. Proc Nat Acad Sci U S A 94, 6541-6546.
36. Misare BD, Krukenkamp IB & Levitsky S (1992). Age-dependent sensitivity to unprotected cardiac ischemia: the senescent myocardium. J Thorac Cardiovasc Surg 103, 60-64.
37. 1 receptor activation. J Am Coll Cardiol 35, 238-245.
38. Pahor M, Di Gennaro M, Cocchi A, Bernabei R, Carosella L & Carbonin P (1985). Age-related incidence of reperfusion- and reoxygenation-induced ventricular tachyarrhythmias in the isolated rat heart. Gerontology 31, 15-26.
39. Peart J, Flood A, Linden J, Matherne GP & Headrick JP (2002). Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart. J Cardiovasc Pharmacol 39, 117-129.
40. 1 adenosine receptors during ischemia and reperfusion improves ischemic tolerance. A m J Physiol Heart Circ Physiol 279, H2166-2175.
41. Qin QN, Downey JM & Cohen MV (2003). Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase. Am J Physiol Heart Circ Physiol 284, H727-734.
42. Ramani K, Lust WD, Whittingham TS & Lesnefsky EJ (1986). ATP catabolism and adenosine generation during ischemia in the aging heart. Mech Ageing Dev 89, 113-124.
43. Rosenfeldt FL, Pepe S, Linnane A, Nagley P, Rowland M, Ou RC, Marasco S & Lyon W (2002). The effects of ageing on the response to cardiac surgery: protective strategies for the ageing myocardium. Biogerontology 3, 37-40.
44. Schulman D, Latchman DS & Yellon DM (2001). Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 281, H1630-1636.
45. Takayama M, Ebihara Y & Tani M (2001). Differences in the expression of protein kinase-C isoforms and its translocation after stimulation with phorbol ester between young-adult and middle-aged ventricular cardiomyocytes isolated from Fischer 344 rats. Jpn Circ J 65, 1071-1076.
46. Takeishi Y, Huang Q, Wang T, Glassman M, Yoshizumi M, Baines CB, Lee JD, Kawakatsu H, Che W, Lerner-Marmarosh N, Zhang C, Yan C, Ohta S, Walsh RA, Berk BC & Abe J (2001). Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: modulation of MAP kinases activation by ischemic preconditioning. J Mol Cell Cardiol 33, 1989-2005.
47. ATP channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts. Cardiovasc Res 49, 56-68.
48. + imbalance. Cardiovasc Res 41, 594-602.
49. Tani M, Suganuma Y, Hasegawa H, Shinmura K, Hayashi Y, Guo X-D & Nakamura Y (1997). Changes in ischemic tolerance and effects of ischemic preconditioning in middle-aged rat hearts. Circulation 95, 2559-2566.
50. Tanno M, Tsuchida A, Nozawa Y, Matsumoto T, Hasegawa T, Miura T & Shimamoto K (2000). Roles of tyrosine kinase and protein kinase C in infarct size limitation by repetitive ischemic preconditioning in the rat. J Cardiovasc Pharmacol 35, 345-352.
51. Tong HY, Chen WN, Steenbergen C & Murphy E (2000). Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C. Circ Res 87, 309-315.
52. ATP channel. Am J Physiol Heart Circ Physiol 266, H829-839.
53. Wang GY Wu S, Pei JM, Yu XC & Wong TM (2001). Kappa- but not delta-opioid receptors mediate effects of ischemic preconditioning on both infarct and arrhythmia in rats. Am J Physiol Heart Circ Physiol 280, H384-391.
54. Zhao ZQ, McGee S, Nakanishi K, Toombs WE, Johnston CF, Ashar MS & Vinten-Johansen J (1993). Receptor-mediated cardioprotective effects of endogenous adenosine are exerted primarily during reperfusion after coronary occlusion in the rabbit. Circulation 88, 709-719.
55. 1 receptor mediated myocardial infarct size reduction by endogenous adenosine is exerted primarily during ischaemia. Cardiovasc Res 28, 270-279.