Block of P2X7 receptors could partly reverse the delayed neuronal death in area CA1 of the hippocampus after transient global cerebral ischemia

Purinergic Signalling

Volumn 9, Issue 4, 2013, Pages 663-675

  Yu, Qiang ^a   Guo, Zhili ^b   Liu, Xiaofeng ^a   Ouyang, Qing ^a   He, Cheng ^a   Burnstock, Geoffrey ^c,d   Yuan, Hongbin ^a   Xiang, Zhenghua ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Delayed neuronal death; Interleukin 1 ; Ischemia reperfusion injury; Microvesicle; P2X7 receptor

Indexed keywords

A 740003; BRILLIANT BLUE G; INTERLEUKIN 1BETA; NEURON SPECIFIC NUCLEAR PROTEIN; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MICROSCOPY; MORRIS WATER MAZE TEST; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; SPATIAL LEARNING; SPATIAL MEMORY; TRANSIENT ISCHEMIC ATTACK; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; HIPPOCAMPUS; ISCHEMIC ATTACK, TRANSIENT; METABOLISM; NERVE CELL; PATHOLOGY; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; HIPPOCAMPUS; ISCHEMIC ATTACK, TRANSIENT; MALE; NEURONS; NEUROPROTECTIVE AGENTS; PURINERGIC P2X RECEPTOR ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2X7; TREATMENT OUTCOME;

EID: 84890550490     PISSN: 15739538     EISSN: 15739546     Source Type: Journal    
DOI: 10.1007/s11302-013-9379-y     Document Type: Article

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