Hypoglycaemia-induced cell death: Features of neuroprotection by the P2 receptor antagonist basilen blue

Neurochemistry International

Volumn 38, Issue 3, 2001, Pages 199-207

  Cavaliere, Fabio ^a   D'Ambrosi, Nadia ^a   Sancesario, Giuseppe ^a,b   Bernardi, Giorgio ^a,b   Volonté, Cinzia ^a,c  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c CNR   (Italy)

Author keywords

Apoptosis; Bcl 2; Caspase 2; Cytochrome c; GRP75 78; HSP70 protein; Necrosis

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 2; CYTOCHROME C; FLUORESCENT DYE; GLUCOSE REGULATED PROTEIN; GLUTAMIC ACID; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; LACTATE DEHYDROGENASE; POTASSIUM; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CHROMATIN; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; HYPOGLYCEMIA; HYPOXIA; NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STRESS;

ANIMALS; APOPTOSIS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASPASES; CELL DEATH; CELLS, CULTURED; CEREBELLUM; COLORING AGENTS; GLUCOSE; HSP70 HEAT-SHOCK PROTEINS; HYPOGLYCEMIA; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; MEMBRANE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2; TRIAZINES;

ANIMALIA;

EID: 0035203874     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(00)00087-5     Document Type: Article

References (43)

1. The Bcl-2 protein family: Arbiters of cell survival
2. Constitutive expression of heat-shock protein 70 in mammalian cells confers thermoresistance
3. Hypoxia induces apoptosis in human neuroblastoma SK-N-MC cells by caspase activation accompanying cytochrome c release from mitochondria
4. Death receptors: Signalling and modulation
5. The role of DNA fragmentation in apoptosis
6. A rapid sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding
7. P2-purinoceptors of two subtypes in the rabbit mesenteric artery: Reactive blue 2 selectively inhibits responses mediated via the P2Y - But not P2X-purinoceptor
8. Oxidative stress, mitochondrial function and acute glutamate excitotoxicity in cultured cerebellar granule cells
9. Basilen blue prevents neuronal cell death following glucose/oxygen deprivation
10. Glucose deprivation and mitochondrial dysfunction: Neuroprotection by P2 receptor antagonists
11. Cyclic AMP and sympathetic neuronal programmed cell death
12. Molecular ordering 0of the cell death pathway
13. NMDA receptor activation inhibits neuronal volume regulation after swelling induced by veratridine-stimulated Na + influx in rat cortical cultures
14. Caspases: The executioners of apoptosis
15. Antagonists of P2 receptors prevent NGF-dependent neuritogenesis in PC12 cells
16. The proteolytic procaspase activation network: An in vitro analysis
17. A matter of life and cell death
18. Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats
19. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
20. Detection of apoptotic or necrotic death in neuronal cells by morphological, biochemical and molecular analysis
21. Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro
22. Involvment of P2 purinoceptors and the nitric oxide pathway in [3H] purine outflow evoked by short term hypoxia and hypoglycaemia in rat hypoccampal slices
23. Medium transitory oxygen-glucose deprivation induced both apoptosis and necrosis in cerebellar granule cells
24. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
25. 2-deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: Evidence for the involvment of stress proteins
26. Preparation of 98% pure cerebellar granule cell cultures
27. Apoptosis, excitotoxicity and neuropathology
28. Preincubation with protein synthesis inhibitors protects cortical neurones against oxygen-glucose deprivation induced cell death
29. Heat shock proteins hsp90 and hsp70 protect neuronal cells from thermal stress but not from programmed cell death
30. Recent advances on neuronal caspases in development and neurodegeneration
31. Binding and functions of extracellular ATP in cultured cerebellar granule neurones
32. Neuronal apoptosis in acute necrotic insults: Why is this subject such a mess?
33. Apoptosis and nervous system
34. Endonucleolytic DNA fragmentation is not required for apoptosis of cultured rat cerebellar granule neurons
35. Heat-shock protein protection
36. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspase-2, -3, -6, -7, -8 and -10 in a caspase-9-dependent manner
37. Mitochondrial release of caspase-2 and -9 during the apoptotic process
38. Bcl-2 regulates a caspase-3/caspase-2 apoptotic cascade in cytosolic extracts
39. Role of high-affinity receptors and membrane transporters in nonsynaptic communication and drug action in the central nervous system
40. Selected P2 receptor modulators prevent glutamate-evoked cytotoxicity in cultured cerebellar granule neurones
41. Biological effects of P2 purinoceptor modulators in cultured primary cerebellar granule neurones
42. Development of a method for measuring cell number: Application to CNS primary neuronal cultures
43. Neuroprotective effects of modulators of P2 receptors in primary culture of CNS neurones