Astrocytic P2Y1 receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 9, 2011, Pages 1930-1941

  Kuboyama, Kazuya ^a   Harada, Hideki ^b   Tozaki Saitoh, Hidetoshi ^a   Tsuda, Makoto ^a   Ushijima, Kazuo ^b   Inoue, Kazuhide ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; astrocytes; ATP; brain ischemia; microglia

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; CXCL2 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 5; MRS 2365; PURINERGIC P2Y1 RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; PYRROLIDINE DITHIOCARBAMATE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR COORDINATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM;

ANIMALS; ASTROCYTES; CEREBRUM; CYTOKINES; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2Y1; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION;

EID: 80052407483     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.49     Document Type: Article

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