Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin

Journal of Cell Science

Volumn 126, Issue 24, 2013, Pages 5598-5609

  Salazar, Valerie S ^a,b   Zarkadis, Nicholas ^a   Huang, Lisa ^a   Watkins, Marcus ^a   Kading, Jacqueline ^a   Bonar, Sheri ^a   Norris, Jin ^a   Mbalaviele, Gabriel ^a   Civitelli, Roberto ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

catenin; Osteoblast; Proliferation; Smad4

Indexed keywords

BETA CATENIN; CYCLIN D1; SMAD1 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN; TRANSCRIPTION FACTOR OSTERIX; WNT3A PROTEIN;

ANIMAL CELL; ARTICLE; BONE MARROW; BONE MINERALIZATION; CALVARIA; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA TRANSCRIPTION; MITOGENESIS; MITOSIS; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOPROGENITOR CELL; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRABECULAR BONE; WNT SIGNALING PATHWAY;

OSTEOBLAST; PROLIFERATION; SMAD4; Β-CATENIN;

ANIMALS; BETA CATENIN; BINDING SITES; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL LINE; CELL PROLIFERATION; CYCLIN D1; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MITOSIS; OSTEOBLASTS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SMAD4 PROTEIN; TRANSCRIPTION, GENETIC; WNT SIGNALING PATHWAY;

EID: 84890513500     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.132233     Document Type: Article

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