Modulation of integrin activation and signaling by α1/α1́-helix unbending at the junction

Journal of Cell Science

Volumn 126, Issue 24, 2013, Pages 5735-5747

  Zhang, Chuanmei ^a,c   Liu, Jiafu ^a   Jiang, Xiuli ^b   Haydar, Nada ^b   Zhang, Can ^a   Shan, Hu ^c   Zhu, Jieqing ^a,b  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c QINGDAO AGRICULTURAL UNIVERSITY   (China)

Author keywords

1 1 helix; Integrin activation; Integrin signaling

Indexed keywords

ALPHA1 BETA3 INTEGRIN; ALPHA2 INTEGRIN; ALPHA5 INTEGRIN; BETA1 INTEGRIN; BETA3 INTEGRIN; F ACTIN; FIBRONECTIN; FOCAL ADHESION KINASE; GLYCINE; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; TALIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL ADHESION; CELL SPREADING; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVATION; FOCAL ADHESION; GENE MUTATION; HYDROGEN BOND; HYDROPHOBICITY; LIGAND BINDING; MODULATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; RESTING STATE NETWORK; SIGNAL TRANSDUCTION; STRESS FIBER; TIGHT JUNCTION;

INTEGRIN ACTIVATION; INTEGRIN SIGNALING; Α1/Α1′-HELIX;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL ADHESION; CHO CELLS; CRICETINAE; CRICETULUS; FIBRINOGEN; HEK293 CELLS; HUMANS; INTEGRIN BETA CHAINS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SIGNAL TRANSDUCTION;

EID: 84890487402     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.137828     Document Type: Article

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