-
1
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
DOI 10.1016/S0092-8674(02)00971-6
-
Hynes, R. O. (2002) Integrins: bi-directional, allosteric, signalling machines Cell 110, 673-687 (Pubitemid 35283958)
-
(2002)
Cell
, vol.110
, Issue.6
, pp. 673-687
-
-
Hynes, R.O.1
-
2
-
-
34247891506
-
Structural basis of integrin regulation and signaling
-
DOI 10.1146/annurev.immunol.25.022106.141618
-
Luo, B. H., Carman, C. V., and Springer, T. A. (2007) Structural basis of integrin regulation and signaling Annu. Rev. Immunol. 25, 619-647 (Pubitemid 46697919)
-
(2007)
Annual Review of Immunology
, vol.25
, pp. 619-647
-
-
Luo, B.-H.1
Carman, C.V.2
Springer, T.A.3
-
3
-
-
0037031906
-
Global conformational earrangements in integrin extracellular domains in outside-in and inside-out signaling
-
DOI 10.1016/S0092-8674(02)00935-2
-
Takagi, J., Petre, B. M., Walz, T., and Springer, T. A. (2002) Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling Cell 110, 599-611 (Pubitemid 35247840)
-
(2002)
Cell
, vol.110
, Issue.5
, pp. 599-611
-
-
Takagi, J.1
Petre, B.M.2
Walz, T.3
Springer, T.A.4
-
4
-
-
0035850669
-
Crystal structure of the extracettutar segment of integrin αVβ3
-
DOI 10.1126/science.1064535
-
Xiong, J. P., Stehle, T., Diefenbach, B., Zhang, R., Dunker, R., Scott, D. L., Joachimiak, A., Goodman, S. L., and Arnaout, M. A. (2001) Crystal structure of the extracellular segment of integrin αVβ3 Science 294, 339-345 (Pubitemid 32963395)
-
(2001)
Science
, vol.294
, Issue.5541
, pp. 339-345
-
-
Xiong, J.-P.1
Stehle, T.2
Diefenbach, B.3
Zhang, R.4
Dunker, R.5
Scott, D.L.6
Joachimiak, A.7
Goodman, S.L.8
Arnaout, M.A.9
-
5
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand
-
DOI 10.1126/science.1069040
-
Xiong, J. P., Stehle, T., Zhang, R., Joachimiak, A., Frech, M., Goodman, S. L., and Arnaout, M. A. (2002) Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand Science 296, 151-155 (Pubitemid 34280076)
-
(2002)
Science
, vol.296
, Issue.5565
, pp. 151-155
-
-
Xiong, J.-P.1
Stehle, T.2
Zhang, R.3
Joachimiak, A.4
Frech, M.5
Goodman, S.L.6
Arnaout, M.A.7
-
6
-
-
57749116060
-
Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces
-
Zhu, J., Luo, B. H., Xiao, T., Zhang, C., Nishida, N., and Springer, T. A. (2008) Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces Mol. Cell 32, 849-861
-
(2008)
Mol. Cell
, vol.32
, pp. 849-861
-
-
Zhu, J.1
Luo, B.H.2
Xiao, T.3
Zhang, C.4
Nishida, N.5
Springer, T.A.6
-
7
-
-
76349099822
-
Structure of an integrin with an alphaI domain, complement receptor type 4
-
Xie, C., Zhu, J., Chen, X., Mi, L., Nishida, N., and Springer, T. A. (2010) Structure of an integrin with an alphaI domain, complement receptor type 4 EMBO J. 29, 666-679
-
(2010)
EMBO J.
, vol.29
, pp. 666-679
-
-
Xie, C.1
Zhu, J.2
Chen, X.3
Mi, L.4
Nishida, N.5
Springer, T.A.6
-
8
-
-
78649680298
-
Structural requirements for activation in alphaIIb beta3 integrin
-
Kamata, T., Handa, M., Ito, S., Sato, Y., Ohtani, T., Kawai, Y., Ikeda, Y., and Aiso, S. (2010) Structural requirements for activation in alphaIIb beta3 integrin J. Biol. Chem. 285, 38428-38437
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 38428-38437
-
-
Kamata, T.1
Handa, M.2
Ito, S.3
Sato, Y.4
Ohtani, T.5
Kawai, Y.6
Ikeda, Y.7
Aiso, S.8
-
9
-
-
77952931584
-
Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3
-
Blue, R., Li, J., Steinberger, J., Murcia, M., Filizola, M., and Coller, B. S. (2010) Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3 J. Biol. Chem. 285, 17604-17613
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17604-17613
-
-
Blue, R.1
Li, J.2
Steinberger, J.3
Murcia, M.4
Filizola, M.5
Coller, B.S.6
-
10
-
-
77949721630
-
Focal adhesions are sites of integrin extension
-
Askari, J. A., Tynan, C. J., Webb, S. E., Martin-Fernandez, M. L., Ballestrem, C., and Humphries, M. J. (2010) Focal adhesions are sites of integrin extension J. Cell Biol. 188, 891-903
-
(2010)
J. Cell Biol.
, vol.188
, pp. 891-903
-
-
Askari, J.A.1
Tynan, C.J.2
Webb, S.E.3
Martin-Fernandez, M.L.4
Ballestrem, C.5
Humphries, M.J.6
-
11
-
-
67649373064
-
The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation
-
Vanhoorelbeke, K., De Meyer, S. F., Pareyn, I., Melchior, C., Plancon, S., Margue, C., Pradier, O., Fondu, P., Kieffer, N., Springer, T. A., and Deckmyn, H. (2009) The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation J. Biol. Chem. 284, 14914-14920
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14914-14920
-
-
Vanhoorelbeke, K.1
De Meyer, S.F.2
Pareyn, I.3
Melchior, C.4
Plancon, S.5
Margue, C.6
Pradier, O.7
Fondu, P.8
Kieffer, N.9
Springer, T.A.10
Deckmyn, H.11
-
12
-
-
64749101260
-
The structure of a receptor with two associating transmembrane domains on the cell surface: Integrin alphaIIbbeta3
-
Zhu, J., Luo, B. H., Barth, P., Schonbrun, J., Baker, D., and Springer, T. A. (2009) The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3 Mol. Cell 34, 234-249
-
(2009)
Mol. Cell
, vol.34
, pp. 234-249
-
-
Zhu, J.1
Luo, B.H.2
Barth, P.3
Schonbrun, J.4
Baker, D.5
Springer, T.A.6
-
13
-
-
70449566822
-
Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation
-
Yang, J., Ma, Y. Q., Page, R. C., Misra, S., Plow, E. F., and J., Q. (2009) Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation Proc. Natl. Acad. Sci. U. S. A. 106, 17729-17734
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 17729-17734
-
-
Yang, J.1
Ma, Y.Q.2
Page, R.C.3
Misra, S.4
Plow, E.F.5
J, Q.6
-
14
-
-
65649127175
-
The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling
-
Lau, T. L., Kim, C., Ginsberg, M. H., and Ulmer, T. S. (2009) The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling EMBO J. 28, 1351-1361
-
(2009)
EMBO J.
, vol.28
, pp. 1351-1361
-
-
Lau, T.L.1
Kim, C.2
Ginsberg, M.H.3
Ulmer, T.S.4
-
15
-
-
33749522074
-
2 Integrins by Conversion from Bent to Extended Conformations
-
DOI 10.1016/j.immuni.2006.07.016, PII S1074761306004274
-
Nishida, N., Xie, C., Shimaoka, M., Cheng, Y., Walz, T., and Springer, T. A. (2006) Activation of leukocyte β2 integrins by conversion from bent to extended conformations Immunity 25, 583-594 (Pubitemid 44529036)
-
(2006)
Immunity
, vol.25
, Issue.4
, pp. 583-594
-
-
Nishida, N.1
Xie, C.2
Shimaoka, M.3
Cheng, Y.4
Walz, T.5
Springer, T.A.6
-
16
-
-
77957034686
-
Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2
-
Chen, X., Xie, C., Nishida, N., Li, Z., Walz, T., and TA., S. (2010) Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2 Proc. Natl. Acad. Sci. U. S. A. 107, 14727-14732
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 14727-14732
-
-
Chen, X.1
Xie, C.2
Nishida, N.3
Li, Z.4
Walz, T.5
Ta, S.6
-
17
-
-
18244364123
-
Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines
-
DOI 10.1038/ni1194
-
Shamri, R., Grabovsky, V., Gauguet, J. M., Feigelson, S., Manevich, E., Kolanus, W., Robinson, M. K., Staunton, D. E., von Andrian, U. H., and Alon, R. (2005) Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines Nature Immunol. 6, 497-506 (Pubitemid 41716763)
-
(2005)
Nature Immunology
, vol.6
, Issue.5
, pp. 497-506
-
-
Shamri, R.1
Grabovsky, V.2
Gauguet, J.-M.3
Feigelson, S.4
Manevich, E.5
Kolanus, W.6
Robinson, M.K.7
Staunton, D.E.8
Von Andrian, U.H.9
Alon, R.10
-
18
-
-
44449139065
-
Intercellular adhesion molecule-3 binding of integrin alphaL beta2 requires both extension and opening of the integrin headpiece
-
Tang, X. Y., Li, Y. F., and SM., T. (2008) Intercellular adhesion molecule-3 binding of integrin alphaL beta2 requires both extension and opening of the integrin headpiece J. Immunol. 180, 4793-4804
-
(2008)
J. Immunol.
, vol.180
, pp. 4793-4804
-
-
Tang, X.Y.1
Li, Y.F.2
Sm, T.3
-
19
-
-
75749154495
-
Recreation of the terminal events in physiological integrin activation
-
Ye, F., Hu, G., Taylor, D., Ratnikov, B., Bobkov, A. A., McLean, M. A., Sligar, S. G., Taylor, K. A., and Ginsberg, M. H. (2010) Recreation of the terminal events in physiological integrin activation J. Cell Biol. 188, 157-173
-
(2010)
J. Cell Biol.
, vol.188
, pp. 157-173
-
-
Ye, F.1
Hu, G.2
Taylor, D.3
Ratnikov, B.4
Bobkov, A.A.5
McLean, M.A.6
Sligar, S.G.7
Taylor, K.A.8
Ginsberg, M.H.9
-
20
-
-
0013307787
-
Conformational changes in the integrin βA domain provide a mechanism for signal transduction via hybrid domain movement
-
DOI 10.1074/jbc.M213139200
-
Mould, A. P., Barton, S. J., Askari, J. A., McEwan, P. A., Buckley, P. A., Craig, S. E., and Humphries, M. J. (2003) Conformational changes in the integrin bA domain provide a mechanism for signal transduction via hybrid domain movement J. Biol. Chem. 278, 17028-17035 (Pubitemid 36799578)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 17028-17035
-
-
Mould, A.P.1
Barton, S.J.2
Askari, J.A.3
McEwan, P.A.4
Buckley, P.A.5
Craig, S.E.6
Humphries, M.J.7
-
21
-
-
1642305349
-
3 Integrin I-like Domain into High and Low Affinity Conformations with Disulfides
-
DOI 10.1074/jbc.M312732200
-
Luo, B. H., Takagi, J., and Springer, T. A. (2004) Locking the β3 integrin I-like domain into high and low affinity conformations with disulfides J. Biol. Chem. 279, 10215-10221 (Pubitemid 38372626)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10215-10221
-
-
Luo, B.-H.1
Takagi, J.2
Springer, T.A.3
-
22
-
-
1442306162
-
Activation of integrin β-subunit I-like domains by one-turn C-terminal α-helix deletions
-
DOI 10.1073/pnas.0307291101
-
Yang, W., Shimaoka, M., Chen, J. F., and Springer, T. A. (2004) Activation of integrin β subunit I-like domains by one-turn C-terminal α-helix deletions Proc. Natl. Acad. Sci. U. S. A. 101, 2333-2338 (Pubitemid 38269312)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.8
, pp. 2333-2338
-
-
Yang, W.1
Shimaoka, M.2
Chen, J.3
Springer, T.A.4
-
23
-
-
63649083644
-
Rationally Designed Integrin b3Mutants Stabilized in the High Affinity Conformation
-
Luo, B. H., Karanicolas, J., Harmacek, L. D., Baker, D., and Springer, T. A. (2009) Rationally Designed Integrin b3Mutants Stabilized in the High Affinity Conformation J. Biol. Chem. 284, 3917-3924
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3917-3924
-
-
Luo, B.H.1
Karanicolas, J.2
Harmacek, L.D.3
Baker, D.4
Springer, T.A.5
-
24
-
-
0029966310
-
Breaking the integrin hinge
-
Hughes, P. E., Diaz-Gonzalez, F., Leong, L., Wu, C., McDonald, J. A., Shattil, S. J., and Ginsberg, M. H. (1996) Breaking the integrin hinge J. Biol. Chem. 271, 6571-6574
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6571-6574
-
-
Hughes, P.E.1
Diaz-Gonzalez, F.2
Leong, L.3
Wu, C.4
McDonald, J.A.5
Shattil, S.J.6
Ginsberg, M.H.7
-
25
-
-
0037031551
-
3 "inside-out" activation as regulated by its cytoplasmic face
-
DOI 10.1016/S0092-8674(02)00906-6
-
3 "inside-out" activation as regulated by its cytoplasmic face Cell 110, 587-597 (Pubitemid 35247839)
-
(2002)
Cell
, vol.110
, Issue.5
, pp. 587-597
-
-
Vinogradova, O.1
Velyvis, A.2
Velyviene, A.3
Hu, B.4
Haas, T.A.5
Plow, E.F.6
Qin, J.7
-
26
-
-
16644396938
-
A specific interface between integrin transmembrane helices and affinity for ligand
-
Luo, B. H., Springer, T. A., and Takagi, J. (2004) A specific interface between integrin transmembrane helices and affinity for ligand PLoS Biol. 2, 776-786
-
(2004)
PLoS Biol.
, vol.2
, pp. 776-786
-
-
Luo, B.H.1
Springer, T.A.2
Takagi, J.3
-
27
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
DOI 10.1126/science.1084174
-
Kim, M., Carman, C. V., and Springer, T. A. (2003) Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins Science 301, 1720-1725 (Pubitemid 37174365)
-
(2003)
Science
, vol.301
, Issue.5640
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
28
-
-
70450222316
-
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
-
Anthis, N. J., Wegener, K. L., Ye, F., Kim, C., Goult, B. T., Lowe, E. D., Vakonakis, I., Bate, N., Critchley, D. R., Ginsberg, M. H., and Campbell, I. D. (2009) The structure of an integrin/talin complex reveals the basis of inside-out signal transduction EMBO J. 28, 3623-3632
-
(2009)
EMBO J.
, vol.28
, pp. 3623-3632
-
-
Anthis, N.J.1
Wegener, K.L.2
Ye, F.3
Kim, C.4
Goult, B.T.5
Lowe, E.D.6
Vakonakis, I.7
Bate, N.8
Critchley, D.R.9
Ginsberg, M.H.10
Campbell, I.D.11
-
29
-
-
78649514202
-
Dissociation of the α-Subunit Calf-2 Domain and the β-Subunit I-EGF4 Domain in Integrin Activation and Signaling
-
Wang, W., Fu, G., and Luo, B. H. (2010) Dissociation of the α-Subunit Calf-2 Domain and the β-Subunit I-EGF4 Domain in Integrin Activation and Signaling Biochemistry 49, 10158-10165
-
(2010)
Biochemistry
, vol.49
, pp. 10158-10165
-
-
Wang, W.1
Fu, G.2
Luo, B.H.3
-
30
-
-
0037418254
-
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand
-
DOI 10.1073/pnas.0438060100
-
Luo, B. H., Springer, T. A., and Takagi, J. (2003) Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand Proc. Natl. Acad. Sci. U. S. A. 100, 2403-2408 (Pubitemid 36297511)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.5
, pp. 2403-2408
-
-
Luo, B.-H.1
Springer, T.A.2
Takagi, J.3
-
31
-
-
34948882323
-
Requirement of α and β subunit transmembrane helix separation for integrin outside-in signaling
-
DOI 10.1182/blood-2007-03-080077
-
Zhu, J., Carman, C. V., Kim, M., Shimaoka, M., Springer, T. A., and Luo, B. H. (2007) Requirement of α and β subunit transmembrane helix separation for integrin outside-in signaling Blood 110, 2475-2483 (Pubitemid 47523169)
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2475-2483
-
-
Zhu, J.1
Carman, C.V.2
Kim, M.3
Shimaoka, M.4
Springer, T.A.5
Luo, B.-H.6
-
32
-
-
33748306120
-
Integrin structures and conformational signaling
-
DOI 10.1016/j.ceb.2006.08.005, PII S0955067406001153
-
Luo, B. H. and Springer, T. A. (2006) Integrin structures and conformational signaling Curr. Opin. Cell Biol. 18, 579-586 (Pubitemid 44332909)
-
(2006)
Current Opinion in Cell Biology
, vol.18
, Issue.5
, pp. 579-586
-
-
Luo, B.-H.1
Springer, T.A.2
-
33
-
-
77954742128
-
Solution properties of full-length integrin alpha(IIb)beta3 refined models suggest environment-dependent induction of alternative bent /extended resting states
-
Rosano, C. and Rocco, M. (2010) Solution properties of full-length integrin alpha(IIb)beta3 refined models suggest environment-dependent induction of alternative bent /extended resting states FEBS J. 277, 3190-3202
-
(2010)
FEBS J.
, vol.277
, pp. 3190-3202
-
-
Rosano, C.1
Rocco, M.2
-
34
-
-
0028285015
-
Integrin cytoplasmic domains mediate inside-out signal transduction
-
OToole, T. E., Katagiri, Y., Faull, R. J., Peter, K., Tamura, R., Quaranta, V., Loftus, J. C., Shattil, S. J., and Ginsberg, M. H. (1994) Integrin cytoplasmic domains mediate inside-out signal transduction J. Cell Biol. 124, 1047-1059 (Pubitemid 24109406)
-
(1994)
Journal of Cell Biology
, vol.124
, Issue.6
, pp. 1047-1059
-
-
O'Toole, T.E.1
Katagiri, Y.2
Faull, R.J.3
Peter, K.4
Tamura, R.5
Quaranta, V.6
Loftus, J.C.7
Shattil, S.J.8
Ginsberg, M.H.9
-
35
-
-
0036220127
-
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
-
DOI 10.1038/nsb779
-
Beglova, N., Blacklow, S. C., Takagi, J., and Springer, T. A. (2002) Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation Nat. Struct. Biol. 9, 282-287 (Pubitemid 34289901)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.4
, pp. 282-287
-
-
Beglova, N.1
Blacklow, S.C.2
Takagi, J.3
Springer, T.A.4
-
36
-
-
0027525561
-
3
-
3 J. Biol. Chem. 268, 23087-23092 (Pubitemid 23328016)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.31
, pp. 23087-23092
-
-
Du, X.1
Gu, M.2
Weisel, J.W.3
Nagaswami, C.4
Bennett, J.S.5
Bowditch, R.6
Ginsberg, M.H.7
-
37
-
-
0035856483
-
Activation of Syk protein tyrosine kinase through interaction with integrin β cytoplasmic domains
-
DOI 10.1016/S0960-9822(01)00565-6
-
Woodside, D., Obergfell, A., Leng, L., Wilsbacher, J. L., Miranti, C. K., Brugge, J. S., Shattil, S. J., and Ginsberg., M. H. (2001) Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains Curr. Biol. 11, 1799-1804 (Pubitemid 33092170)
-
(2001)
Current Biology
, vol.11
, Issue.22
, pp. 1799-1804
-
-
Woodside, D.G.1
Obergfell, A.2
Leng, L.3
Wilsbacher, J.L.4
Miranti, C.K.5
Brugge, J.S.6
Shattil, S.J.7
Ginsberg, M.H.8
-
38
-
-
0037131428
-
The N-terminal SH2 domains of Syk and ZAP-70 mediate phosphotyrosine- independent binding to integrin β cytoplasmic domains
-
DOI 10.1074/jbc.M207657200
-
Woodside, D. G., Obergfell, A., Talapatra, A., Calderwood, D. A., Shattil, S. J., and Ginsberg, M. H. (2002) The N-terminal SH2 domains of syk and ZAP-70 mediate phosphotyrosine-independent binding to integrin β cytoplasmic domains J. Biol. Chem. 277, 39401-39408 (Pubitemid 35190914)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39401-39408
-
-
Woodside, D.G.1
Obergfell, A.2
Talapatra, A.3
Calderwood, D.A.4
Shattil, S.J.5
Ginsberg, M.H.6
-
39
-
-
0345687176
-
Src kinase activation by direct interaction with the integrin β cytoplasmic domain
-
DOI 10.1073/pnas.2336149100
-
Arias-Salgado, E. G., Lizano, S., Sarkar, S., Brugge, J. S., Ginsberg, M. H., and Shattil, S. J. (2003) Src kinase activation by direct interaction with the integrin β cytoplasmic domain Proc. Natl. Acad. Sci. U. S. A. 100, 13298-13302 (Pubitemid 37444736)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.23
, pp. 13298-13302
-
-
Arias-Salgado, E.G.1
Lizano, S.2
Sarkar, S.3
Brugge, J.S.4
Ginsberg, M.H.5
Shattil, S.J.6
-
40
-
-
0141865705
-
Talin binding to integrin β tails: A final common step in integrin activation
-
DOI 10.1126/science.1086652
-
Tadokoro, S., Shattil, S. J., Eto, K., Tai, V., Liddington, R. C., de Pereda, J. M., Ginsberg, M. H., and Calderwood, D. A. (2003) Talin binding to integrin β tails: a final common step in integrin activation Science 302, 103-106 (Pubitemid 37210697)
-
(2003)
Science
, vol.302
, Issue.5642
, pp. 103-106
-
-
Tadokoro, S.1
Shattil, S.J.2
Eto, K.3
Tai, V.4
Liddington, R.C.5
De Pereda, J.M.6
Ginsberg, M.H.7
Calderwood, D.A.8
-
41
-
-
0141625303
-
Structure of integrin α5β1 in complex with fibronectin
-
Takagi, J., Strokovich, K., Springer, T. A., and Walz, T. (2003) Structure of integrin α5β1 in complex with fibronectin EMBO J. 22, 4607-4615
-
(2003)
EMBO J.
, vol.22
, pp. 4607-4615
-
-
Takagi, J.1
Strokovich, K.2
Springer, T.A.3
Walz, T.4
-
42
-
-
34249685565
-
Tests of the extension and deadbolt models of integrin activation
-
DOI 10.1074/jbc.M700249200
-
Zhu, J., Boylan, B., Luo, B. H., Newman, P. J., and Springer, T. A. (2007) Tests of the extension and deadbolt models of integrin activation J. Biol. Chem. 16, 11914-11920 (Pubitemid 47100725)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.16
, pp. 11914-11920
-
-
Zhu, J.1
Boylan, B.2
Luo, B.-H.3
Newman, P.J.4
Springer, T.A.5
-
43
-
-
11244258886
-
7
-
DOI 10.1074/jbc.M407773200
-
Chen, J. F., Takagi, J., Xie, C., Xiao, T., Luo, B. H., and Springer, T. A. (2004) The relative influence of metal ion binding sites in the I-like domain and the interface with the hybrid domain on rolling and firm adhesion by integrin a4b7 J. Biol. Chem. 279, 55556-55561 (Pubitemid 40066558)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.53
, pp. 55556-55561
-
-
Chen, J.1
Takagi, J.2
Xie, C.3
Xiao, T.4
Luo, B.-H.5
Springer, T.A.6
-
44
-
-
77949758937
-
Outside-in signal transmission by conformational changes in integrin Mac-1
-
Lefort, C. T., Hyun, Y. M., Schultz, J. B., Law, F. Y., Waugh, R. E., Knauf, P. A., and Kim, M. (2009) Outside-in signal transmission by conformational changes in integrin Mac-1 J. Immunol. 183, 6460-6468
-
(2009)
J. Immunol.
, vol.183
, pp. 6460-6468
-
-
Lefort, C.T.1
Hyun, Y.M.2
Schultz, J.B.3
Law, F.Y.4
Waugh, R.E.5
Knauf, P.A.6
Kim, M.7
-
45
-
-
78751526817
-
Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signaling
-
Wang, W., Zhu, J., Springer, T. A., and Luo, B. H. (2011) Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signaling J. Biol. Chem. 286, 1860-1867
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1860-1867
-
-
Wang, W.1
Zhu, J.2
Springer, T.A.3
Luo, B.H.4
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