Promoter methylation status of MGMT, hMSH2, and hMLH1 and its relationship to corresponding protein expression and TP53 mutations in human esophageal squamous cell carcinoma

Medical Oncology

Volumn 31, Issue 2, 2014, Pages

  Su, Yaoyao ^a   Yin, Lihong ^a   Liu, Ran ^a   Sheng, Jing Yi ^a   Yang, Miao ^a   Wang, Yi ^b   Pan, Enchun ^b   Guo, Wei ^c   Pu, Yuepu ^a   Zhang, Juan ^a   Liang, Geyu ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b Huaian Center for Disease Control and Prevention   (China)

^c THE AFFILIATED HUAIAN NO 1 PEOPLE S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Human esophageal squamous cell carcinoma; Promoter methylation; TP53 mutation

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MUTL HOMOLOG 1; UNCLASSIFIED DRUG; DNA; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; MICROSATELLITE DNA; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN MSH2; PROTEIN P53; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TP53 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; EXON; GENE MUTATION; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; WESTERN BLOTTING; CANCER GRADING; COMPARATIVE STUDY; DNA REPAIR; ESOPHAGUS; ESOPHAGUS TUMOR; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR; DNA REPAIR ENZYMES; DNA, NEOPLASM; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; HUMANS; MICROSATELLITE REPEATS; MUTATION; MUTS HOMOLOG 2 PROTEIN; NEOPLASM GRADING; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROGNOSIS; PROMOTER REGIONS, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84890470225     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-013-0784-4     Document Type: Article

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