Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis

DNA Repair

Volumn 2, Issue 10, 2003, Pages 1135-1146

  Takagi, Yasumitsu ^a   Takahashi, Masayuki ^b   Sanada, Masayuki ^a   Ito, Riyoko ^a   Yamaizumi, Masaru ^c   Sekiguchi, Mutsuo ^a,d  

^a FUKUOKA DENTAL COLLEGE   (Japan)

^b UNIVERSITÉ DE NANTES   (France)

^c KUMAMOTO UNIVERSITY   (Japan)

^d BIOMOL ENG RESEARCH INSTITUTE   (Japan)

Author keywords

Alkylating agents; Apoptosis; DNA repair methyltransferase; Mismatch recognition; Mutagenesis

Indexed keywords

ALKYLATING AGENT; CARCINOGEN; CASPASE 3; COMPLEMENTARY DNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITROSOUREA; METHYLTRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN; PROTEIN MLH1; UNCLASSIFIED DRUG; CARRIER PROTEIN; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, MOUSE; CASPASE; MLH1 PROTEIN, HUMAN; MLH1 PROTEIN, MOUSE; NUCLEAR PROTEIN; TUMOR PROTEIN;

ALKYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE MUTATION; GENE TARGETING; MALE; MISMATCH REPAIR; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; WILD TYPE; ANIMAL; APOPTOSIS; BASE MISPAIRING; DNA DAMAGE; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION; PHYSIOLOGY; TIME; TUMOR CELL LINE;

ALKYLATING AGENTS; ALKYLATION; ANIMALS; APOPTOSIS; BASE PAIR MISMATCH; CARRIER PROTEINS; CASPASE 3; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; DNA DAMAGE; METHYLNITROSOUREA; MICE; MICE, KNOCKOUT; MUTAGENESIS; MUTATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; TIME FACTORS;

EID: 1542366109     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(03)00134-4     Document Type: Article

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