Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma

Carcinogenesis

Volumn 23, Issue 10, 2002, Pages 1713-1720

  Nie, Yan ^a   Liao, Jie ^a   Zhao, Xin ^a,b   Song, Yunlong ^a   Yang, Guang Yu ^a   Wang, Li Dong ^b   Yang, Chung S ^a  

^a RUTGERS UNIVERSITY   (United States)

^b University Zhengzhou   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DNA; FRAGILE HISTIDINE TRIAD PROTEIN; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; PROTEIN MLH1; PROTEIN P14; PROTEIN P15; PROTEIN P16; PROTEIN P53; UVOMORULIN;

ARTICLE; BASAL CELL; CANCER RISK; CANCER SURGERY; CANCER TISSUE; CARCINOGENESIS; CARCINOMA IN SITU; CELL HYPERPLASIA; CHEMICAL MODIFICATION; CONTROLLED STUDY; CPG ISLAND; DISSECTION; DNA EXTRACTION; DNA METHYLATION; DYSPLASIA; EPITHELIUM CELL; ESOPHAGUS CARCINOMA; FREQUENCY ANALYSIS; GENE CLUSTER; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LASER; NUCLEOTIDE SEQUENCE; PRECANCER; PREDICTION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY;

EID: 0036799084     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/23.10.1713     Document Type: Article

References (38)

1. Parkin,D.M., Pisani,P. and Ferlay,J. (1993) Estimates of the worldwide incidence of eighteen major cancers in 1985. Int. J. Cancer, 54, 594-606.
2. Yang,C.S. (1980) Research on esophageal cancer in China: a review. Cancer Res., 40, 2633-2644.
3. Yang,C.S. (1982) Nitrosamines and other etiological factors in the esophageal cancer in Northern China. In Magee,P.N. (ed.) Nitrosamines In Human Cancer. Cold Spring Harbor Laboratory, New York, pp. 587-501.
4. Morgan,G.R (1995) Epidemiology of oesophageal cancer. J. Roy. Soc. Med., 88, 119.
5. Bollschweiler,E. and Holscher,A.H. (2001) [Carcinoma of the esophagusactual epidemiology in Germany]. Onkologie, 24, 180-184.
6. Xing,E.P., Yang,G.Y, Wang,L.D., Shi,S.T. and Yang,C.S. (1999) Loss of heterozygosity of the Rb gene correlates with pRb protein expression and associates with p53 alteration in human esophageal cancer. Clin. Cancer Res., 5, 1231-1240.
7. Xing,E.R, Nie,Y., Wang,L.D., Yang,G.Y. and Yang,C.S. (1999) Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China. Carcinogenesis, 20, 77-84.
8. Xing,E.P., Nie,Y., Song,Y., Yang,G.Y., Cai,YC., Wang,L.D. and Yang,C.S. (1999) Mechanisms of inactivation of p14ARF, p15INK4b and p16INK4a genes in human esophageal squamous cell carcinoma. Clin. Cancer Res., 5, 2704-2713.
9. Wang,L.D., Hong,J.Y, Qiu,,S.L., Gao,H. and Yang,C.S. (1993) Accumulation of p53 protein in human esophageal precancerous lesions: a possible early biomarker for carcinogenesis. Cancer Res., 53, 1783-1787.
10. Gao,H., Wang,L.D., Zhou,Q., Hong,J.Y, Huang,T.Y and Yang,C.S. (1994) p53 tumor suppressor gene mutation in early esophageal precancerous lesions and carcinoma among high-risk populations in Henan, China. Cancer Res., 54, 4342-4346.
11. Nie,Y, Yang,G.-Y, Song,Y, Zhao,X., So,C., Liao,J., Wang,L.-D. and Yang,C.S. (2001) DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas. Carcinogenesis, 22, 1615-1623.
12. Tanaka,H., Shimada,Y, Harada,H., Shinoda,M., Hatooka,S., Imamura,M. and Ishizaki,K. (1998) Methylation of the 5′ CpG island of the FHIT gene is closely associated with transcriptional inactivation in esophageal squamous cell carcinomas. Cancer Res., 58, 3429-3434.
13. Sugimura,T. and Ushijima,T. (2000) Genetic and epigenetic alterations in carcinogenesis. Mutat. Res., 462, 235-246.
14. Momparler,R.L. and Bovenzi,V. (2000) DNA methylation and cancer. J. Cell. Physiol., 183, 145-154.
15. Baylin,S.B., Herman,J.G., Graff,J.R., Vertino,P.M. and Issa,J.P. (1998) Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res., 72, 141-196.
16. Robertson,K.D. and Jones,P.A. (2000) DNA methylation: past, present and future directions. Carcinogenesis, 21, 461-467.
17. Jones,P.A. (2001) Cancer. Death and methylation. Nature, 409, 141, 143-144.
18. Tate,P.H. and Brid,A.P. (1993) Effects of DNA methylation on DNAbinding proteins and gene expression. Curr. Opin. Genet. Dev., 3, 226-231.
19. Kass,S.U., Pruss,D. and Wolffe,A.R (1997) How does DNA methylation repress transcription? Trends Genet., 13, 444-449.
20. Bird,A.P. and Wolffe,A.P. (1999) Methylation-induced repression-belts, braces and chromatin. Cell, 99, 451-454.
21. Hendrich,B. and Bird,A. (2000) Mammalian methyltransferases and methyl-CpG-binding domains: proteins involved in DNA methylation. Curr. Top. Microbiol. Immunol., 249, 55-74.
22. Nan,X., Ng,H.H., Johnson,C.A., Laherty,C.D., Turner,B.M., Eisenman,R.N. and Bird,A. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature, 393, 386-389.
23. Rountree,M.R., Bachman,K.E. and Baylin,S.B. (2000) DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nature Genet., 25, 269-277.
24. Jones,P.A. and Laird,P.W. (1999) Cancer epigenetics comes of age. Nature Genet., 21, 163-167.
25. Costello,J.F., Fruhwald,M.C., Smiraglia,D.J. et al. (2000) Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nature Genet., 24, 132-138.
26. Dong,G., Loukinova,E., Chen,Z., Gangi,L., Chanturita,T.I., Liu,E.T. and Van Waes,C. (2001) Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple genes related to growth, apoptosis, angiogenesis and the NF-kappaB signal pathway. Cancer Res., 61, 4797-4808.
27. Jiang,H., Kang,D.C., Alexandre,D. and Fisher,P.B. (2000) RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes. Proc. Natl Acad. Sci. USA, 97, 12684-12689.
28. Velculescu,V.E., Zhang,L., Vogelstein,B. and Kinzler,K.W. (1995) Serial analysis of gene expression. Science, 270, 484-487.
29. Perou,C.M., Sorlie,T., Eisen,M.B., et al. (2000) Molecular portraits of human breast tumours. Nature, 406, 747-752.
30. Loeb,L.A. (2001) A mutator phenotype in cancer. Cancer Res., 61, 3230-3239.
31. Huebner,K., Garrison,P.N., Barnes,L.D. and Croce,C.M. (1998) The role of the FHIT/FRA3B locus in cancer. Anna. Rev. Genet., 32, 7-31.
32. Shimada,Y., Sato,F., Watanabe,G., Yamasaki,S., Kato,M., Maeda,M. and Imamura,M. (2000) Loss of fragile histidine triad gene expression is associated with progression of esophageal squamous cell carcinoma, but not with the patient's prognosis and smoking history. Cancer, 89, 5-11.
33. Graff,J.R., Herman,J.G., Myohanen,S., Baylin,S.B. and Vertino,P.M. (1997) Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation. J. Biol. Chem., 272, 22322-22329.
34. Hermam, J.G., Graff,J.R., Myohanen,S., Nelkin,B.D. and Baylin,S.B. (1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl Acad. Sci. USA, 93, 9821-9826.
35. Leung,W.K., Yu,J., Ng,E.K., To,K.F., Ma,P.K., Lee,T.L., Go,M.Y., Chung,S.C. and Sung,J.J. (2001) Concurrent hypermethylation of multiple tumor-related genes in gastric carcinoma and adjacent normal tissues. Cancer, 91, 2294-2301.
36. Montesano,R., Hollstein,M. and Hainaut,P. (1996) Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review. Int. J. Cancer, 69, 225-235.
37. Baylin,S.B., Esteller,M., Rountree,M.R., Bachman,K.E., Schuebel,K. and Herman,J.G. (2001) Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum. Mol. Genet., 10, 687-692.
38. Herman,J.G., Umar,A., Polyak,K., et al. (1998) Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl Acad. Sci. USA, 95, 6870-6875