Dual-functionalized PAMAM dendrimers with improved P-glycoprotein inhibition and tight junction modulating effect

Biomacromolecules

Volumn 14, Issue 12, 2013, Pages 4226-4235

  Liu, Yuanjie ^a   Chiu, Gigi N C ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

FUNCTIONALIZATIONS; MODULATING EFFECT; ORAL DRUG DELIVERY; POLY(AMIDO AMINE); SURFACE-MODIFIED; TIGHT JUNCTIONS; TRANSEPITHELIAL ELECTRICAL RESISTANCES; WEIGHT ESTIMATION;

DRUG DELIVERY; FUNCTIONAL GROUPS; GLYCOPROTEINS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

DENDRIMERS;

4 THIOBUTYLAMIDINE; AMIDINE; DENDRIMER; DRUG CARRIER; FUNCTIONAL GROUP; GLYCOPROTEIN; LACTATE DEHYDROGENASE; LUCIFER YELLOW; MACROGOL; POLYAMIDOAMINE; PROTEIN ZO1; RHODAMINE 123; THIOL GROUP; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ELECTRIC RESISTANCE; ENZYME RELEASE; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MDCK CELL; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SURFACE PROPERTY; TIGHT JUNCTION; TRANSEPITHELIAL ELECTRICAL RESISTANCE;

AMIDINES; ANIMALS; CACO-2 CELLS; DENDRIMERS; DOGS; DRUG CARRIERS; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; P-GLYCOPROTEIN; PARTICLE SIZE; PERMEABILITY; POLYETHYLENE GLYCOLS; TIGHT JUNCTIONS;

EID: 84890384663     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm401057c     Document Type: Article

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