Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: Characterization of the process and possible mechanisms involved

Particle and Fibre Toxicology

Volumn 10, Issue 1, 2013, Pages

  Longhin, Eleonora ^a   Holme, Jørn A ^b   Gutzkow, Kristine B ^b   Arlt, Volker M ^c   Kucab, Jill E ^c   Camatini, Marina ^a   Gualtieri, Maurizio ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

BEAS 2B; CYP enzymes; Mitotic arrest; PM2.5; ROS

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALPHA NAPHTHOFLAVONE; ANTIOXIDANT; CHECKPOINT KINASE 2; CYCLIN B1; CYTOCHROME P450; HISTONE H2AX; ORGANIC MATTER; PHOSPHORUS 32; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

ANAPHASE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CANCER INCIDENCE; CELL ACTIVITY; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE CHECKPOINT; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL LABELING; CHROMOSOME ABERRATION; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA DETERMINATION; DOUBLE STRANDED DNA BREAK; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG CANCER; METABOLIC ACTIVATION; METAPHASE; MICRONUCLEUS; MITOSIS; MITOSIS SLIPPAGE; MITOSIS SPINDLE; MOLECULAR MECHANICS; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; SINGLE STRANDED DNA BREAK; SPINDLE APPARATUS; TETRAPLOIDY; TIME SERIES ANALYSIS; URBAN AREA; WESTERN BLOTTING; WINTER;

AIR POLLUTANTS; BLOTTING, WESTERN; BRONCHI; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE; DNA DAMAGE; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; ITALY; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICROSCOPY, FLUORESCENCE; MITOSIS; PARTICLE SIZE; PARTICULATE MATTER; REACTIVE OXYGEN SPECIES; SEASONS; SPINDLE APPARATUS; TETRAPLOIDY; URBANIZATION;

EID: 84890378745     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-10-63     Document Type: Article

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