Genotoxic effects of carbon black particles, diesel exhaust particles, and urban air particulates and their extracts on a human alveolar epithelial cell line (A549) and a human monocytic cell line (THP-1)

Environmental and Molecular Mutagenesis

Volumn 37, Issue 2, 2001, Pages 155-163

  Carero, A Don Porto ^a   Hoet, P H M ^b   Verschaeve, L ^a   Schoeters, G ^a   Nemery, B ^b  

^a FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

A549 epithelial lung cells; Carbon black; Diesel exhaust particles; Genotoxicity; THP 1 macrophages; Urban particulate matter

Indexed keywords

CARBON; DICHLOROMETHANE; METAL; SILICATE;

AIR POLLUTANT; ARTICLE; CARCINOGENICITY; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; EXHAUST GAS; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; MONOCYTE; PARTICULATE MATTER;

AIR POLLUTANTS; CARBON; CELL LINE; COMET ASSAY; HUMANS; MONOCYTES; MUTAGENS; PARTICLE SIZE; PULMONARY ALVEOLI; VEHICLE EMISSIONS;

EID: 0035068237     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.1023     Document Type: Article

References (25)

1. Paraquat induced DNA damage by reactive oxygen species
2. The human leukemia cell line, THP-I: A multifaceted model for the study of monocyte-macrophage differentiation
3. The atmospheric cycle of elemental carbon
4. Health effects of diesel exhaust: Epidemiology
5. Lung cancer and air pollution
6. Does diesel exhaust cause human lung cancer?
7. 3Hthymidine incorporation assay
8. Responses of alveolar macrophages and epithelial type II cells to oxidative DNA damage caused by paraquat
9. Methodology and technology for animal inhalation toxicology studies
10. Particulate air pollution and respiratory disease in Anchorage, Alaska
11. Comparative investigation on the genotoxicity of city smog and automobile exhaust particulates
12. Induction of sister chromatid exchanges in rodent tracheal epithelial cells as a sensitive bioassay for detection of genotoxic activity of airborne particulates
13. Sister chromatid exchanges in rodent tracheal epithelium exposed in vitro to environmental pollutants
14. Diesel engine exhaust
15. Carbon black
16. Free radical effects on lung metabolism
17. Pathophysiology and biochemical mechanisms of the pulmonary toxicity of paraquat
18. Weighing the health risks of airborne particulates
19. Genotoxic evaluation of the herbicide paraquat in cultured human lymphocytes
20. Mutagenic nitroarenes, diesel emissions, particulate-induced mutations and cancer: An essay on cancer-causation by a moving target
21. Effect of airborne particulates on phagocytosis of human and rat macrophages
22. Comparative genotoxicity testing of airborne particulates using rodent tracheal epithelial cells and human lymphocytes in vitro
23. A simple technique for quantitation of low levels of DNA damage in individual cells
24. Study on the mutagenicity of diesel exhaust particles
25. Chemical mixtures in atmospheric aerosols and their correlation to lung diseases and lung cancer occurrence in the general population