-
1
-
-
0032802378
-
Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast
-
Alarcon, C.M., J. Heitman, and M.E. Cardenas. 1999. Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. Mol. Biol. Cell. 10:2531-2546. http://dx.doi.org/10.1091/mbc.10.8.2531
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 2531-2546
-
-
Alarcon, C.M.1
Heitman, J.2
Cardenas, M.E.3
-
2
-
-
33751523289
-
Fission yeast Tor2 promotes cell growth and represses cell differentiation
-
Alvarez, B., and S. Moreno. 2006. Fission yeast Tor2 promotes cell growth and represses cell differentiation. J. Cell Sci. 119:4475-4485. http://dx.doi.org/10.1242/jcs.03241
-
(2006)
J. Cell Sci
, vol.119
, pp. 4475-4485
-
-
Alvarez, B.1
Moreno, S.2
-
3
-
-
0027441494
-
TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility
-
Basi, G., E. Schmid, and K. Maundrell. 1993. TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility. Gene. 123:131-136. http://dx.doi.org/10.1016/0378-1119(93)90552-E
-
(1993)
Gene
, vol.123
, pp. 131-136
-
-
Basi, G.1
Schmid, E.2
Maundrell, K.3
-
4
-
-
18044380709
-
Systematic deletion analysis of fission yeast protein kinases
-
Bimbó, A., Y. Jia, S.L. Poh, R.K. Karuturi, N. den Elzen, X. Peng, L. Zheng, M. O'Connell, E.T. Liu, M.K. Balasubramanian, and J. Liu. 2005. Systematic deletion analysis of fission yeast protein kinases. Eukaryot. Cell. 4:799-813. http://dx.doi.org/10.1128/EC.4.4.799-813.2005
-
(2005)
Eukaryot. Cell
, vol.4
, pp. 799-813
-
-
Bimbó, A.1
Jia, Y.2
Poh, S.L.3
Karuturi, R.K.4
Den Elzen, N.5
Peng, X.6
Zheng, L.7
O'Connell, M.8
Liu, E.T.9
Balasubramanian, M.K.10
Liu, J.11
-
5
-
-
0033956543
-
Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9
-
Caspari, T., M. Dahlen, G. Kanter-Smoler, H.D. Lindsay, K. Hofmann, K. Papadimitriou, P. Sunnerhagen, and A.M. Carr. 2000. Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9. Mol. Cell. Biol. 20:1254-1262. http://dx.doi.org/10.1128/MCB.20.4.1254-1262.2000
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 1254-1262
-
-
Caspari, T.1
Dahlen, M.2
Kanter-Smoler, G.3
Lindsay, H.D.4
Hofmann, K.5
Papadimitriou, K.6
Sunnerhagen, P.7
Carr, A.M.8
-
6
-
-
84862137469
-
Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation
-
Chang, X., A.S. Lazorchak, D. Liu, and B. Su. 2012. Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation. Eur. J. Immunol. 42:1639-1647. http://dx.doi.org/10.1002/eji.201142066
-
(2012)
Eur. J. Immunol
, vol.42
, pp. 1639-1647
-
-
Chang, X.1
Lazorchak, A.S.2
Liu, D.3
Su, B.4
-
7
-
-
62449266454
-
TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2
-
Copp, J., G. Manning, and T. Hunter. 2009. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Res. 69:1821-1827. http://dx.doi.org/10.1158/0008-5472.CAN-08-3014
-
(2009)
Cancer Res
, vol.69
, pp. 1821-1827
-
-
Copp, J.1
Manning, G.2
Hunter, T.3
-
8
-
-
84964878137
-
TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast
-
Du, W., L. Hálová, S. Kirkham, J. Atkin, and J. Petersen. 2012. TORC2 and the AGC kinase Gad8 regulate phosphorylation of the ribosomal protein S6 in fission yeast. Biol. Open. 1:884-888. http://dx.doi.org/10.1242/bio.20122022
-
(2012)
Biol. Open
, vol.1
, pp. 884-888
-
-
Du, W.1
Hálová, L.2
Kirkham, S.3
Atkin, J.4
Petersen, J.5
-
9
-
-
0028051665
-
Assessment of pheromone production and response in fission yeast by a halo test of induced sporulation
-
Egel, R., M. Willer, S. Kjaerulff, J. Davey, and O. Nielsen. 1994. Assessment of pheromone production and response in fission yeast by a halo test of induced sporulation. Yeast. 10:1347-1354. http://dx.doi.org/10.1002/yea.320101012
-
(1994)
Yeast
, vol.10
, pp. 1347-1354
-
-
Egel, R.1
Willer, M.2
Kjaerulff, S.3
Davey, J.4
Nielsen, O.5
-
10
-
-
0017389881
-
Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division
-
Fantes, P., and P. Nurse. 1977. Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division. Exp. Cell Res. 107:377-386. http://dx.doi.org/10.1016/0014-4827(77)90359-7
-
(1977)
Exp. Cell Res
, vol.107
, pp. 377-386
-
-
Fantes, P.1
Nurse, P.2
-
11
-
-
36749055217
-
Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits
-
Hayashi, T., M. Hatanaka, K. Nagao, Y. Nakaseko, J. Kanoh, A. Kokubu, M. Ebe, and M. Yanagida. 2007. Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits. Genes Cells. 12:1357-1370. http://dx.doi.org/10.1111/j.1365-2443.2007.01141.x
-
(2007)
Genes Cells
, vol.12
, pp. 1357-1370
-
-
Hayashi, T.1
Hatanaka, M.2
Nagao, K.3
Nakaseko, Y.4
Kanoh, J.5
Kokubu, A.6
Ebe, M.7
Yanagida, M.8
-
12
-
-
81055140318
-
The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe
-
Ikai, N., N. Nakazawa, T. Hayashi, and M. Yanagida. 2011. The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe. Open Biol. 1:110007. http://dx.doi.org/10.1098/rsob.110007
-
(2011)
Open Biol
, vol.1
, pp. 110007
-
-
Ikai, N.1
Nakazawa, N.2
Hayashi, T.3
Yanagida, M.4
-
13
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto, E., V. Facchinetti, D. Liu, N. Soto, S. Wei, S.Y. Jung, Q. Huang, J. Qin, and B. Su. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 127:125-137. http://dx.doi.org/10.1016/j.cell.2006.08.033
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
Soto, N.4
Wei, S.5
Jung, S.Y.6
Huang, Q.7
Qin, J.8
Su, B.9
-
14
-
-
84861719535
-
Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia
-
Lee, K., K.T. Nam, S.H. Cho, P. Gudapati, Y. Hwang, D.S. Park, R. Potter, J. Chen, E. Volanakis, and M. Boothby. 2012. Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. J. Exp. Med. 209:713-728. http://dx.doi.org/10.1084/jem.20111470
-
(2012)
J. Exp. Med
, vol.209
, pp. 713-728
-
-
Lee, K.1
Nam, K.T.2
Cho, S.H.3
Gudapati, P.4
Hwang, Y.5
Park, D.S.6
Potter, R.7
Chen, J.8
Volanakis, E.9
Boothby, M.10
-
15
-
-
83455177213
-
Target of rapamycin (TOR) in nutrient signaling and growth control
-
Loewith, R., and M.N. Hall. 2011. Target of rapamycin (TOR) in nutrient signaling and growth control. Genetics. 189:1177-1201. http://dx.doi.org/10.1534/genetics.111.133363
-
(2011)
Genetics
, vol.189
, pp. 1177-1201
-
-
Loewith, R.1
Hall, M.N.2
-
16
-
-
18044381192
-
Rheb binds and regulates the mTOR kinase
-
Long, X., Y. Lin, S. Ortiz-Vega, K. Yonezawa, and J. Avruch. 2005. Rheb binds and regulates the mTOR kinase. Curr. Biol. 15:702-713. http://dx.doi.org/10.1016/j.cub.2005.02.053
-
(2005)
Curr. Biol
, vol.15
, pp. 702-713
-
-
Long, X.1
Lin, Y.2
Ortiz-Vega, S.3
Yonezawa, K.4
Avruch, J.5
-
17
-
-
0036021402
-
Role of the Tsc1-Tsc2 complex in signaling and transport across the cell membrane in the fission yeast Schizosaccharomyces pombe
-
Matsumoto, S., A. Bandyopadhyay, D.J. Kwiatkowski, U. Maitra, and T. Matsumoto. 2002. Role of the Tsc1-Tsc2 complex in signaling and transport across the cell membrane in the fission yeast Schizosaccharomyces pombe. Genetics. 161:1053-1063.
-
(2002)
Genetics
, vol.161
, pp. 1053-1063
-
-
Matsumoto, S.1
Bandyopadhyay, A.2
Kwiatkowski, D.J.3
Maitra, U.4
Matsumoto, T.5
-
18
-
-
0037600512
-
Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases
-
Matsuo, T., Y. Kubo, Y. Watanabe, and M. Yamamoto. 2003. Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases. EMBO J. 22:3073-3083. http://dx.doi.org/10.1093/emboj/cdg298
-
(2003)
EMBO J
, vol.22
, pp. 3073-3083
-
-
Matsuo, T.1
Kubo, Y.2
Watanabe, Y.3
Yamamoto, M.4
-
19
-
-
34147207884
-
Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast
-
Matsuo, T., Y. Otsubo, J. Urano, F. Tamanoi, and M. Yamamoto. 2007. Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast. Mol. Cell. Biol. 27:3154-3164. http://dx.doi.org/10.1128/MCB.01039-06
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3154-3164
-
-
Matsuo, T.1
Otsubo, Y.2
Urano, J.3
Tamanoi, F.4
Yamamoto, M.5
-
20
-
-
77149141403
-
Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin
-
Nakashima, A., T. Sato, and F. Tamanoi. 2010. Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin. J. Cell Sci. 123:777-786. http://dx.doi.org/10.1242/jcs.060319
-
(2010)
J. Cell Sci
, vol.123
, pp. 777-786
-
-
Nakashima, A.1
Sato, T.2
Tamanoi, F.3
-
21
-
-
79960470913
-
mTOR complex 2 signaling and functions
-
Oh, W.J., and E. Jacinto. 2011. mTOR complex 2 signaling and functions. Cell Cycle. 10:2305-2316. http://dx.doi.org/10.4161/cc.10.14.16586
-
(2011)
Cell Cycle
, vol.10
, pp. 2305-2316
-
-
Oh, W.J.1
Jacinto, E.2
-
22
-
-
0026355413
-
Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations
-
Pearson, R.B., and B.E. Kemp. 1991. Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations. Methods Enzymol. 200:62-81. http://dx.doi.org/10.1016/0076-6879(91)00127-I
-
(1991)
Methods Enzymol
, vol.200
, pp. 62-81
-
-
Pearson, R.B.1
Kemp, B.E.2
-
23
-
-
35748973557
-
TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases
-
Petersen, J., and P. Nurse. 2007. TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases. Nat. Cell Biol. 9:1263-1272. http://dx.doi.org/10.1038/ncb1646
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 1263-1272
-
-
Petersen, J.1
Nurse, P.2
-
24
-
-
33846024055
-
Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p
-
Reinke, A., J.C. Chen, S. Aronova, and T. Powers. 2006. Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p. J. Biol. Chem. 281:31616-31626. http://dx.doi.org/10.1074/jbc.M603107200
-
(2006)
J. Biol. Chem
, vol.281
, pp. 31616-31626
-
-
Reinke, A.1
Chen, J.C.2
Aronova, S.3
Powers, T.4
-
25
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
Sancak, Y., T.R. Peterson, Y.D. Shaul, R.A. Lindquist, C.C. Thoreen, L. Bar-Peled, and D.M. Sabatini. 2008. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 320:1496-1501. http://dx.doi.org/10.1126/science.1157535
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
26
-
-
21244480367
-
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
-
Smith, E.M., S.G. Finn, A.R. Tee, G.J. Browne, and C.G. Proud. 2005. The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses. J. Biol. Chem. 280:18717-18727. http://dx.doi.org/10.1074/jbc.M414499200
-
(2005)
J. Biol. Chem
, vol.280
, pp. 18717-18727
-
-
Smith, E.M.1
Finn, S.G.2
Tee, A.R.3
Browne, G.J.4
Proud, C.G.5
-
27
-
-
77954235821
-
Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy
-
Sparks, C.A., and D.A. Guertin. 2010. Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy. Oncogene. 29:3733-3744. http://dx.doi.org/10.1038/onc.2010.139
-
(2010)
Oncogene
, vol.29
, pp. 3733-3744
-
-
Sparks, C.A.1
Guertin, D.A.2
-
28
-
-
79952044837
-
Rab small GTPase emerges as a regulator of TOR complex 2
-
Tatebe, H., and K. Shiozaki. 2010. Rab small GTPase emerges as a regulator of TOR complex 2. Small GTPases. 1:180-182. http://dx.doi.org/10.4161/sgtp.1.3.14936
-
(2010)
Small GTPases
, vol.1
, pp. 180-182
-
-
Tatebe, H.1
Shiozaki, K.2
-
29
-
-
78649316549
-
Rab-family GTPase regulates TOR complex 2 signaling in fission yeast
-
Tatebe, H., S. Morigasaki, S. Murayama, C.T. Zeng, and K. Shiozaki. 2010. Rab-family GTPase regulates TOR complex 2 signaling in fission yeast. Curr. Biol. 20:1975-1982. http://dx.doi.org/10.1016/j.cub.2010.10.026
-
(2010)
Curr. Biol
, vol.20
, pp. 1975-1982
-
-
Tatebe, H.1
Morigasaki, S.2
Murayama, S.3
Zeng, C.T.4
Shiozaki, K.5
-
30
-
-
33847651745
-
Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells
-
Urano, J., T. Sato, T. Matsuo, Y. Otsubo, M. Yamamoto, and F. Tamanoi. 2007. Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells. Proc. Natl. Acad. Sci. USA. 104:3514-3519. http://dx.doi.org/10.1073/pnas.0608510104
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3514-3519
-
-
Urano, J.1
Sato, T.2
Matsuo, T.3
Otsubo, Y.4
Yamamoto, M.5
Tamanoi, F.6
-
31
-
-
33751190328
-
Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase
-
Uritani, M., H. Hidaka, Y. Hotta, M. Ueno, T. Ushimaru, and T. Toda. 2006. Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase. Genes Cells. 11:1367-1379. http://dx.doi.org/10.1111/j.1365-2443.2006.01025.x
-
(2006)
Genes Cells
, vol.11
, pp. 1367-1379
-
-
Uritani, M.1
Hidaka, H.2
Hotta, Y.3
Ueno, M.4
Ushimaru, T.5
Toda, T.6
-
32
-
-
1842424927
-
Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe
-
van Slegtenhorst, M., E. Carr, R. Stoyanova, W.D. Kruger, and E.P. Henske. 2004. Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe. J. Biol. Chem. 279:12706-12713. http://dx.doi.org/10.1074/jbc.M313874200
-
(2004)
J. Biol. Chem
, vol.279
, pp. 12706-12713
-
-
van Slegtenhorst, M.1
Carr, E.2
Stoyanova, R.3
Kruger, W.D.4
Henske, E.P.5
-
33
-
-
37049028325
-
Gene tagging and gene replacement using recombinase-mediated cassette exchange in Schizosaccharomyces pombe
-
Watson, A.T., V. Garcia, N. Bone, A.M. Carr, and J. Armstrong. 2008. Gene tagging and gene replacement using recombinase-mediated cassette exchange in Schizosaccharomyces pombe. Gene. 407:63-74. http://dx.doi.org/10.1016/j.gene.2007.09.024
-
(2008)
Gene
, vol.407
, pp. 63-74
-
-
Watson, A.T.1
Garcia, V.2
Bone, N.3
Carr, A.M.4
Armstrong, J.5
-
34
-
-
0035831446
-
The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine
-
Weisman, R., and M. Choder. 2001. The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine. J. Biol. Chem. 276:7027-7032. http://dx.doi.org/10.1074/jbc.M010446200
-
(2001)
J. Biol. Chem
, vol.276
, pp. 7027-7032
-
-
Weisman, R.1
Choder, M.2
-
35
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger, S., R. Loewith, and M.N. Hall. 2006. TOR signaling in growth and metabolism. Cell. 124:471-484. http://dx.doi.org/10.1016/j.cell.2006.01.016
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
36
-
-
84877761058
-
mTOR kinase structure, mechanism and regulation
-
Yang, H., D.G. Rudge, J.D. Koos, B. Vaidialingam, H.J. Yang, and N.P. Pavletich. 2013. mTOR kinase structure, mechanism and regulation. Nature. 497:217-223. http://dx.doi.org/10.1038/nature12122
-
(2013)
Nature
, vol.497
, pp. 217-223
-
-
Yang, H.1
Rudge, D.G.2
Koos, J.D.3
Vaidialingam, B.4
Yang, H.J.5
Pavletich, N.P.6
|