Tuning up the right signal: Chemical and genetic approaches to study GPCR functions

Current Opinion in Cell Biology

Volumn 27, Issue 1, 2014, Pages 51-55

  Giguere, Patrick M ^a   Kroeze, Wesley K ^a   Roth, Bryan L ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; CHEMOKINE RECEPTOR CXCR4; CLOZAPINE N OXIDE; DESIGNER DRUG; ERGOTAMINE; G PROTEIN COUPLED RECEPTOR; LYSERGIDE; RETINA S ANTIGEN; RIZATRIPTAN; SEROTONIN 2B RECEPTOR;

CELLULAR DISTRIBUTION; CHEMICAL GENETICS; CRYSTAL STRUCTURE; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENE TARGETING; HUMAN; MICROENVIRONMENT; NONHUMAN; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR INTRINSIC ACTIVITY; REVIEW; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DEVELOPMENT; GENETICS; METABOLISM; MOLECULAR BIOLOGY; PHARMACOLOGY; PROTEIN ENGINEERING; REPRODUCIBILITY;

ANIMALS; DRUG DISCOVERY; HUMANS; MOLECULAR BIOLOGY; PHARMACOLOGY; PROTEIN ENGINEERING; RECEPTORS, G-PROTEIN-COUPLED; REPRODUCIBILITY OF RESULTS;

EID: 84890035606     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.11.006     Document Type: Review

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