Design and functional characterization of a novel, arrestin-biased designer G protein-coupled receptor

Molecular Pharmacology

Volumn 82, Issue 4, 2012, Pages 575-582

  Nakajima, Ken Ichiro ^a   Wess, Jürgen ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARRESTIN 2; ARRESTIN 3; CLOZAPINE N OXIDE; G PROTEIN COUPLED RECEPTOR; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCARINIC M3 RECEPTOR; TISSUE ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; EMBRYO; ENZYME PHOSPHORYLATION; GENE CONSTRUCT; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULIN RESISTANCE; INSULINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

AMINO ACID MOTIFS; ANIMALS; ARRESTIN; CALCIUM; CELL LINE; CERCOPITHECUS AETHIOPS; CLOZAPINE; CYCLIC AMP; GENE KNOCKDOWN TECHNIQUES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; POINT MUTATION; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; RADIOLIGAND ASSAY; RECEPTOR, MUSCARINIC M3; SIGNAL TRANSDUCTION;

EID: 84866868206     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.080358     Document Type: Article

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