Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation

Acta Crystallographica Section D: Biological Crystallography

Volumn 69, Issue 12, 2013, Pages 2563-2579

  Cherry, Amy L ^a   Finta, Csaba ^a   Karlström, Mikael ^a   Jin, Qianren ^a   Schwend, Thomas ^a   Astorga Wells, Juan ^a,b   Zubarev, Roman A ^a   Del Campo, Mark ^c   Criswell, Angela R ^c   De Sanctis, Daniele ^d   Jovine, Luca ^a   Toftgård, Rune ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Biomotif AB   (Sweden)

^c RIGAKU CORPORATION   (Japan)

^d EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

Author keywords

GLI; Hedgehog signalling regulation; SUFU

Indexed keywords

GLI1 PROTEIN, HUMAN; REPRESSOR PROTEIN; SUFU PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; GLI; HEDGEHOG; HEDGEHOG SIGNALLING REGULATION; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUFU; X RAY CRYSTALLOGRAPHY;

GLI; HEDGEHOG SIGNALLING REGULATION; SUFU;

AMINO ACID SEQUENCE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; HEDGEHOGS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84889832303     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444913028473     Document Type: Article

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