Heterogeneity of familial medulloblastoma and contribution of germline PTCH1 and SUFU mutations to sporadic medulloblastoma

Familial Cancer

Volumn 10, Issue 2, 2011, Pages 337-342

  Slade, Ingrid ^a   Murray, Anne ^a   Hanks, Sandra ^a   Kumar, Ajith ^b   Walker, Lisa ^c   Hargrave, Darren ^a   Douglas, Jenny ^a   Stiller, Charles ^d   Izatt, Louise ^e   Rahman, Nazneen ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^c CHURCHILL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Familial medulloblastoma; Medulloblastoma; PTCH1; SUFU; Tumor predisposition

Indexed keywords

GENOMIC DNA; PROTEIN PATCHED 1; SUFU PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BRAIN TUMOR; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DESMOPLASTIC MEDULLOBLASTOMA; DNA SEQUENCE; FAMILIAL CANCER; FAMILIAL MEDULLOBLASTOMA; GENE IDENTIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC SUSCEPTIBILITY; GERM LINE; HUMAN; MAJOR CLINICAL STUDY; MEDULLOBLASTOMA; MULTIPLEX POLYMERASE CHAIN REACTION; NUCLEOTIDE SEQUENCE; PEDIGREE; PHENOTYPE; PRIORITY JOURNAL; SOMATIC MUTATION; SPORADIC MEDULLOBLASTOMA;

ADULT; AGED; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; GERM-LINE MUTATION; HUMANS; MALE; MEDULLOBLASTOMA; MIDDLE AGED; RECEPTORS, CELL SURFACE; REPRESSOR PROTEINS;

ERINACEIDAE;

EID: 79958127479     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-010-9411-0     Document Type: Article

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