Dual phosphorylation of suppressor of fused (Sufu) by PKA and GSK3β regulates its stability and localization in the primary cilium

Journal of Biological Chemistry

Volumn 286, Issue 15, 2011, Pages 13502-13511

  Chen, Yan ^a,b   Yue, Shen ^a   Xie, Lu ^a   Pu, Xiao Hong ^a   Jin, Tian ^b   Cheng, Steven Y ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACIDS; CILIARY LOCALIZATION; DEPHOSPHORYLATIONS; DUAL SITES; NEGATIVE REGULATORS; PHOSPHORYLATION SITES; PRIMARY CILIUM; PROTEIN KINASE A; SONIC HEDGEHOGS; UBIQUITIN-PROTEASOME SYSTEM;

AMINO ACIDS; ORGANIC ACIDS;

PHOSPHORYLATION;

ALANINE; ASPARTIC ACID; CELL PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; SERINE; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; SUPPRESSOR OF FUSED PROTEIN; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; EUKARYOTIC FLAGELLUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANIMALS; CILIA; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GLYCOGEN SYNTHASE KINASE 3; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MUTATION, MISSENSE; NERVE TISSUE PROTEINS; NIH 3T3 CELLS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; PROTEIN TRANSPORT; REPRESSOR PROTEINS; UBIQUITIN;

ERINACEIDAE;

EID: 79953858623     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.217604     Document Type: Article

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