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Volumn 5, Issue 4, 2013, Pages 1655-1675

Long non-coding RNAs embedded in the Rb and p53 pathways

Author keywords

Cell cycle; lncRNA; miRNA; p53; Rb

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENHANCER RNA; LINCRNA ROR; LNCRNA ANRIL; LNCRNA GADD7; LNCRNA H19; LNCRNA HULC; LNCRNA KCNQ1OT1; LNCRNA LOC285194; LNCRNA MALAT1; LNCRNA MEG3; LNCRNA P21; LNCRNA P21 ASSOCIATED NCRNA DNA DAMAGE ACTIVATED; LONG UNTRANSLATED RNA; NCRNA CYCLIN D1; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84889774884     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers5041655     Document Type: Review
Times cited : (33)

References (122)
  • 1
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R.A. The retinoblastoma protein and cell cycle control. Cell 1995, 81, 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 2
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A.J. p53, the cellular gatekeeper for growth and division. Cell 1997, 88, 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 4
  • 5
    • 84862777719 scopus 로고    scopus 로고
    • Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells
    • Li, M.; He, Y.; Dubois, W.; Wu, X.; Shi, J.; Huang, J. Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells. Mol. Cell 2012, 46, 30-42.
    • (2012) Mol. Cell , vol.46 , pp. 30-42
    • Li, M.1    He, Y.2    Dubois, W.3    Wu, X.4    Shi, J.5    Huang, J.6
  • 6
    • 0033967393 scopus 로고    scopus 로고
    • The role of p53-target genes in human cancer
    • Tokino, T.; Nakamura, Y. The role of p53-target genes in human cancer. Crit. Rev. Oncol. Hematol. 2000, 33, 1-6.
    • (2000) Crit. Rev. Oncol. Hematol. , vol.33 , pp. 1-6
    • Tokino, T.1    Nakamura, Y.2
  • 7
    • 0032931517 scopus 로고    scopus 로고
    • The p53 pathway
    • Prives, C.; Hall, P.A. The p53 pathway. J. Pathol. 1999, 187, 112-126.
    • (1999) J. Pathol. , vol.187 , pp. 112-126
    • Prives, C.1    Hall, P.A.2
  • 8
    • 0032952004 scopus 로고    scopus 로고
    • Mdm2: The ups and downs
    • Juven-Gershon, T.; Oren, M. Mdm2: The ups and downs. Mol. Med. 1999, 5, 71-83.
    • (1999) Mol. Med. , vol.5 , pp. 71-83
    • Juven-Gershon, T.1    Oren, M.2
  • 9
    • 0033118592 scopus 로고    scopus 로고
    • Control of the cell cycle and apoptosis
    • Lundberg, A.S.; Weinberg, R.A. Control of the cell cycle and apoptosis. Eur. J. Cancer 1999, 35, 531-539.
    • (1999) Eur. J. Cancer , vol.35 , pp. 531-539
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 10
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D.O. Principles of CDK regulation. Nature 1995, 374, 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 11
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • Sherr, C.J.; McCormick, F. The RB and p53 pathways in cancer. Cancer Cell 2002, 2, 103-112.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 12
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr, C.J.; Roberts, J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 1995, 9, 1149-1163.
    • (1995) Genes Dev. , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 13
    • 0033082231 scopus 로고    scopus 로고
    • RB regulates the stability and the apoptotic function of p53 via MDM2
    • Hsieh, J.K.; Chan, F.S.; O'Connor, D.J.; Mittnacht, S.; Zhong, S.; Lu, X. RB regulates the stability and the apoptotic function of p53 via MDM2. Mol. Cell 1999, 3, 181-193.
    • (1999) Mol. Cell , vol.3 , pp. 181-193
    • Hsieh, J.K.1    Chan, F.S.2    O'Connor, D.J.3    Mittnacht, S.4    Zhong, S.5    Lu, X.6
  • 14
    • 52949129831 scopus 로고    scopus 로고
    • Circular reasoning: MicroRNAs and cell-cycle control
    • Chivukula, R.R.; Mendell, J.T. Circular reasoning: microRNAs and cell-cycle control. Trends Biochem. Sci. 2008, 33, 474-481.
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 474-481
    • Chivukula, R.R.1    Mendell, J.T.2
  • 15
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz, W.; Bhattacharyya, S.N.; Sonenberg, N. Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat. Rev. Genet. 2008, 2008, 102-114.
    • (2008) Nat. Rev. Genet. , vol.2008 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 17
    • 52649088391 scopus 로고    scopus 로고
    • miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
    • Liu, Q.; Fu, H.; Sun, F.; Zhang, H.; Tie, Y.; Zhu, J.; Xing, R.; Sun, Z.; Zheng, X. miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res. 2008, 36, 5391-5404.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 5391-5404
    • Liu, Q.1    Fu, H.2    Sun, F.3    Zhang, H.4    Tie, Y.5    Zhu, J.6    Xing, R.7    Sun, Z.8    Zheng, X.9
  • 19
    • 46349109152 scopus 로고    scopus 로고
    • Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
    • Pierson, J.; Hostager, B.; Fan, R.; Vibhakar, R. Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J. Neurooncol. 2008, 90, 1-7.
    • (2008) J. Neurooncol. , vol.90 , pp. 1-7
    • Pierson, J.1    Hostager, B.2    Fan, R.3    Vibhakar, R.4
  • 21
    • 42049092138 scopus 로고    scopus 로고
    • Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest
    • Sun, F.; Fu, H.; Liu, Q.; Tie, Y.; Zhu, J.; Xing, R.; Sun, Z.; Zheng, X. Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest. FEBS Lett. 2008, 582, 1564-1568.
    • (2008) FEBS Lett. , vol.582 , pp. 1564-1568
    • Sun, F.1    Fu, H.2    Liu, Q.3    Tie, Y.4    Zhu, J.5    Xing, R.6    Sun, Z.7    Zheng, X.8
  • 23
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-microRNAs with a role in cancer
    • Esquela-Kerscher, A.; Slack, F.J. Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer 2006, 6, 259-269.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 24
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • Mercer, T.R.; Dinger, M.E.; Mattick, J.S. Long non-coding RNAs: Insights into functions. Nat. Rev. Genet. 2009, 10, 155-159.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 25
    • 23044437498 scopus 로고    scopus 로고
    • RNA meets chromatin
    • Bernstein, E.; Allis, C.D. RNA meets chromatin. Genes Dev. 2005, 19, 1635-1655.
    • (2005) Genes Dev. , vol.19 , pp. 1635-1655
    • Bernstein, E.1    Allis, C.D.2
  • 26
    • 70350500219 scopus 로고    scopus 로고
    • Polycomb group proteins: Navigators of lineage pathways led astray in cancer
    • Bracken, A.P.; Helin, K. Polycomb group proteins: Navigators of lineage pathways led astray in cancer. Nat. Rev. Cancer 2009, 9, 773-784.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 773-784
    • Bracken, A.P.1    Helin, K.2
  • 27
    • 67649671961 scopus 로고    scopus 로고
    • Long noncoding RNAs: Functional surprises from the RNA world
    • Wilusz, J.E.; Sunwoo, H.; Spector, D.L. Long noncoding RNAs: Functional surprises from the RNA world. Genes Dev. 2009, 23, 1494-1504.
    • (2009) Genes Dev. , vol.23 , pp. 1494-1504
    • Wilusz, J.E.1    Sunwoo, H.2    Spector, D.L.3
  • 28
    • 79957840356 scopus 로고    scopus 로고
    • Long noncoding RNAs and human disease
    • Wapinski, O.; Chang, H.Y. Long noncoding RNAs and human disease. Trends Cell Biol. 2011, 21, 354-361.
    • (2011) Trends Cell Biol. , vol.21 , pp. 354-361
    • Wapinski, O.1    Chang, H.Y.2
  • 31
    • 69249235745 scopus 로고    scopus 로고
    • Lessons from X-chromosome inactivation: Long ncRNA as guides and tethers to the epigenome
    • Lee, J.T. Lessons from X-chromosome inactivation: Long ncRNA as guides and tethers to the epigenome. Genes Dev. 2009, 23, 1831-1842.
    • (2009) Genes Dev. , vol.23 , pp. 1831-1842
    • Lee, J.T.1
  • 32
    • 69249216410 scopus 로고    scopus 로고
    • A "higher order" of telomere regulation: Telomere heterochromatin and telomeric RNAs
    • Schoeftner, S.; Blasco, M.A. A "higher order" of telomere regulation: Telomere heterochromatin and telomeric RNAs. EMBO J. 2009, 28, 2323-2336.
    • (2009) EMBO J. , vol.28 , pp. 2323-2336
    • Schoeftner, S.1    Blasco, M.A.2
  • 33
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno, L.; Salmena, L.; Zhang, J.; Carver, B.; Haveman, W.J.; Pandolfi, P.P. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010, 465, 1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 34
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller, M. Non-coding RNAs in human disease. Nat. Rev. Genet. 2011, 12, 861-874.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 861-874
    • Esteller, M.1
  • 35
    • 84884191636 scopus 로고    scopus 로고
    • Long non-coding RNAs and complex human diseases
    • Li, J.; Xuan, Z.; Liu, C. Long non-coding RNAs and complex human diseases. IJMS 2013, 14, 18790-18808.
    • (2013) IJMS , vol.14 , pp. 18790-18808
    • Li, J.1    Xuan, Z.2    Liu, C.3
  • 39
    • 84865379361 scopus 로고    scopus 로고
    • LincRNA-p21 suppresses target mRNA translation
    • Yoon, J.H.; Abdelmohsen, K.; Srikantan, S.; Yang, X. LincRNA-p21 suppresses target mRNA translation. Mol. Cell 2012, 47, 648-655.
    • (2012) Mol. Cell , vol.47 , pp. 648-655
    • Yoon, J.H.1    Abdelmohsen, K.2    Srikantan, S.3    Yang, X.4
  • 40
    • 84887320810 scopus 로고    scopus 로고
    • Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer
    • Zhai, H.; Fesler, A.; Schee, K.; Fodstad, O.; Flatmark, K.; Ju, J. Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer. Clin. Colorectal Cancer 2013, 12, 261-266.
    • (2013) Clin. Colorectal Cancer , vol.12 , pp. 261-266
    • Zhai, H.1    Fesler, A.2    Schee, K.3    Fodstad, O.4    Flatmark, K.5    Ju, J.6
  • 42
    • 6744221197 scopus 로고    scopus 로고
    • Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q
    • Miyoshi, N.; Wagatsuma, H.; Wakana, S.; Shiroishi, T.; Nomura, M.; Aisaka, K.; Kohda, T.; Surani, M.A.; Kaneko-Ishino, T.; Ishino, F. Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q. Genes Cells 2000, 5, 211-220.
    • (2000) Genes Cells , vol.5 , pp. 211-220
    • Miyoshi, N.1    Wagatsuma, H.2    Wakana, S.3    Shiroishi, T.4    Nomura, M.5    Aisaka, K.6    Kohda, T.7    Surani, M.A.8    Kaneko-Ishino, T.9    Ishino, F.10
  • 43
    • 84887212367 scopus 로고    scopus 로고
    • At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1
    • Hagan, J.P.; O'Neill, B.L.; Stewart, C.L.; Kozlov, S.V.; Croce, C.M. At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1. PLoS One 2009, 4, e4352.
    • (2009) PLoS One , vol.4
    • Hagan, J.P.1    O'Neill, B.L.2    Stewart, C.L.3    Kozlov, S.V.4    Croce, C.M.5
  • 44
    • 0345172377 scopus 로고    scopus 로고
    • A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells
    • Zhang, X. A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells. J. Clin. Endocrinol. Metab. 2003, 88, 5119-5126.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 5119-5126
    • Zhang, X.1
  • 46
    • 77149157495 scopus 로고    scopus 로고
    • Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: Isoform structure, expression, and functions
    • Zhang, X.; Rice, K.; Wang, Y.; Chen, W.; Zhong, Y.; Nakayama, Y.; Zhou, Y.; Klibanski, A. Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: Isoform structure, expression, and functions. Endocrinology 2010, 151, 939-947.
    • (2010) Endocrinology , vol.151 , pp. 939-947
    • Zhang, X.1    Rice, K.2    Wang, Y.3    Chen, W.4    Zhong, Y.5    Nakayama, Y.6    Zhou, Y.7    Klibanski, A.8
  • 50
  • 51
  • 54
    • 84864315112 scopus 로고    scopus 로고
    • The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult
    • Zhang, B.; Arun, G.; Mao, Y.S.; Lazar, Z.; Hung, G.; Bhattacharjee, G.; Xiao, X.; Booth, C.J.; Wu, J.; Zhang, C.; et al. The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Rep. 2012, 2, 111-123.
    • (2012) Cell Rep. , vol.2 , pp. 111-123
    • Zhang, B.1    Arun, G.2    Mao, Y.S.3    Lazar, Z.4    Hung, G.5    Bhattacharjee, G.6    Xiao, X.7    Booth, C.J.8    Wu, J.9    Zhang, C.10
  • 56
    • 84863219731 scopus 로고    scopus 로고
    • The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r
    • Keniry, A.; Oxley, D.; Monnier, P.; Kyba, M.; Dandolo, L.; Smits, G.; Reik, W. The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat. Cell Biol. 2012, 14, 659-665.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 659-665
    • Keniry, A.1    Oxley, D.2    Monnier, P.3    Kyba, M.4    Dandolo, L.5    Smits, G.6    Reik, W.7
  • 57
    • 18244369516 scopus 로고    scopus 로고
    • Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1
    • Weksberg, R.; Nishikawa, J.; Caluseriu, O.; Fei, Y.L.; Shuman, C.; Wei, C.; Steele, L.; Cameron, J.; Smith, A.; Ambus, I.; et al. Tumor development in the Beckwith-Wiedemann syndrome is associated with a variety of constitutional molecular 11p15 alterations including imprinting defects of KCNQ1OT1. Hum. Mol. Genet. 2001, 10, 2989-3000.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2989-3000
    • Weksberg, R.1    Nishikawa, J.2    Caluseriu, O.3    Fei, Y.L.4    Shuman, C.5    Wei, C.6    Steele, L.7    Cameron, J.8    Smith, A.9    Ambus, I.10
  • 58
    • 18744406710 scopus 로고    scopus 로고
    • ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome
    • Arima, T. ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith-Wiedemann syndrome. Nucleic Acids Res. 2005, 33, 2650-2660.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 2650-2660
    • Arima, T.1
  • 59
    • 33646598385 scopus 로고    scopus 로고
    • Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes
    • Mancini-DiNardo, D.; Steele, S.J.S.; Levorse, J.M.; Ingram, R.S.; Tilghman, S.M. Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. Genes Dev. 2006, 20, 1268-1282.
    • (2006) Genes Dev. , vol.20 , pp. 1268-1282
    • Mancini-DiNardo, D.1    Steele, S.J.S.2    Levorse, J.M.3    Ingram, R.S.4    Tilghman, S.M.5
  • 63
    • 84886025386 scopus 로고    scopus 로고
    • A novel tetranucleotide repeat polymorphism within KCNQ1OT1 confers risk for hepatocellular carcinoma
    • Wan, J.; Huang, M.; Zhao, H.; Wang, C.; Zhao, X.; Jiang, X.; Bian, S.; He, Y.; Gao, Y. A novel tetranucleotide repeat polymorphism within KCNQ1OT1 confers risk for hepatocellular carcinoma. DNA Cell Biol. 2013, 32, 628-634.
    • (2013) DNA Cell Biol , vol.32 , pp. 628-634
    • Wan, J.1    Huang, M.2    Zhao, H.3    Wang, C.4    Zhao, X.5    Jiang, X.6    Bian, S.7    He, Y.8    Gao, Y.9
  • 64
    • 34248547495 scopus 로고    scopus 로고
    • Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: Identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF
    • Pasmant, E.; Laurendeau, I.; Héron, D.; Vidaud, M.; Vidaud, D.; Bièche, I. Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: Identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF. Cancer Res. 2007, 67, 3963-3969.
    • (2007) Cancer Res. , vol.67 , pp. 3963-3969
    • Pasmant, E.1    Laurendeau, I.2    Héron, D.3    Vidaud, M.4    Vidaud, D.5    Bièche, I.6
  • 65
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • Yap, K.L.; Li, S.; Muñoz-Cabello, A.M.; Raguz, S.; Zeng, L.; Mujtaba, S.; Gil, J.; Walsh, M.J.; Zhou, M.-M. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol. Cell 2010, 38, 662-674.
    • (2010) Mol. Cell , vol.38 , pp. 662-674
    • Yap, K.L.1    Li, S.2    Muñoz-Cabello, A.M.3    Raguz, S.4    Zeng, L.5    Mujtaba, S.6    Gil, J.7    Walsh, M.J.8    Zhou, M.-M.9
  • 66
    • 79955468280 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
    • Kotake, Y.; Nakagawa, T.; Kitagawa, K.; Suzuki, S.; Liu, N.; Kitagawa, M.; Xiong, Y. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene 2011, 30, 1956-1962.
    • (2011) Oncogene , vol.30 , pp. 1956-1962
    • Kotake, Y.1    Nakagawa, T.2    Kitagawa, K.3    Suzuki, S.4    Liu, N.5    Kitagawa, M.6    Xiong, Y.7
  • 67
    • 84874969813 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway
    • Wan, G.; Mathur, R.; Hu, X.; Liu, Y.; Zhang, X.; Peng, G.; Lu, X. Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway. Cell. Signal. 2013, 25, 1086-1095.
    • (2013) Cell. Signal. , vol.25 , pp. 1086-1095
    • Wan, G.1    Mathur, R.2    Hu, X.3    Liu, Y.4    Zhang, X.5    Peng, G.6    Lu, X.7
  • 69
    • 84864387239 scopus 로고    scopus 로고
    • Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18
    • Du, Y.; Kong, G.; You, X.; Zhang, S.; Zhang, T.; Gao, Y.; Ye, L.; Zhang, X. Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. J. Biol. Chem. 2012, 287, 26302-26311.
    • (2012) J. Biol. Chem. , vol.287 , pp. 26302-26311
    • Du, Y.1    Kong, G.2    You, X.3    Zhang, S.4    Zhang, T.5    Gao, Y.6    Ye, L.7    Zhang, X.8
  • 70
    • 77956542998 scopus 로고    scopus 로고
    • CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer
    • Wang, J.; Liu, X.; Wu, H.; Ni, P.; Gu, Z.; Qiao, Y.; Chen, N.; Sun, F.; Fan, Q. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res. 2010, 38, 5366-5383.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5366-5383
    • Wang, J.1    Liu, X.2    Wu, H.3    Ni, P.4    Gu, Z.5    Qiao, Y.6    Chen, N.7    Sun, F.8    Fan, Q.9
  • 72
    • 0029984631 scopus 로고    scopus 로고
    • A novel DNA damage-inducible transcript, gadd7, inhibits cell growth, but lacks a protein product
    • Hollander, M.C.; Alamo, I.; Fornace, A.J. A novel DNA damage-inducible transcript, gadd7, inhibits cell growth, but lacks a protein product. Nucleic Acids Res. 1996, 24, 1589-1593.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1589-1593
    • Hollander, M.C.1    Alamo, I.2    Fornace, A.J.3
  • 73
    • 0030726447 scopus 로고    scopus 로고
    • Identification of several human homologs of hamster DNA damage-inducible transcripts cloning and characterization of a novel uv-inducible cDNA that codes for a putative RNA-binding protein
    • Hollander, M.C.; Zhan, Q.; Yu, K.; Fornace, A.J. Identification of several human homologs of hamster DNA damage-inducible transcripts cloning and characterization of a novel uv-inducible cDNA that codes for a putative RNA-binding protein. J. Biol. Chem. 1997, 272, 26720-26726.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26720-26726
    • Hollander, M.C.1    Zhan, Q.2    Yu, K.3    Fornace, A.J.4
  • 74
    • 84863488058 scopus 로고    scopus 로고
    • MicroRNAs, wild-type and mutant p53: More questions than answers
    • Jones, M.; Lal, A. MicroRNAs, wild-type and mutant p53: More questions than answers. RNA Biol. 2012, 9, 781-791.
    • (2012) RNA Biol. , vol.9 , pp. 781-791
    • Jones, M.1    Lal, A.2
  • 77
    • 84877754579 scopus 로고    scopus 로고
    • Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells
    • Özgür, E.; Mert, U.; Isin, M.; Okutan, M.; Dalay, N.; Gezer, U. Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells. Clin. Exp. Med. 2013, 13, 119-126.
    • (2013) Clin. Exp. Med. , vol.13 , pp. 119-126
    • Özgür, E.1    Mert, U.2    Isin, M.3    Okutan, M.4    Dalay, N.5    Gezer, U.6
  • 78
    • 79953888460 scopus 로고    scopus 로고
    • The functional role of long non-coding RNA in human carcinomas
    • Gibb, E.A.; Brown, C.J.; Lam, W.L. The functional role of long non-coding RNA in human carcinomas. Mol. Cancer 2011, 10, e38.
    • (2011) Mol. Cancer , vol.10
    • Gibb, E.A.1    Brown, C.J.2    Lam, W.L.3
  • 79
    • 29444457713 scopus 로고    scopus 로고
    • Rapid evolution of noncoding RNAs: Lack of conservation does not mean lack of function
    • Pang, K.C.; Frith, M.C.; Mattick, J.S. Rapid evolution of noncoding RNAs: Lack of conservation does not mean lack of function. Trends Genet. 2006, 22, 1-5.
    • (2006) Trends Genet. , vol.22 , pp. 1-5
    • Pang, K.C.1    Frith, M.C.2    Mattick, J.S.3
  • 80
    • 75149191872 scopus 로고    scopus 로고
    • Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma
    • Pasic, I.; Shlien, A.; Durbin, A.D.; Stavropoulos, D.J.; Baskin, B.; Ray, P.N.; Novokmet, A.; Malkin, D. Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma. Cancer Res. 2010, 70, 160-171.
    • (2010) Cancer Res. , vol.70 , pp. 160-171
    • Pasic, I.1    Shlien, A.2    Durbin, A.D.3    Stavropoulos, D.J.4    Baskin, B.5    Ray, P.N.6    Novokmet, A.7    Malkin, D.8
  • 81
    • 0344429906 scopus 로고    scopus 로고
    • MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
    • Ji, P.; Diederichs, S.; Wang, W.; Böing, S.; Metzger, R.; Schneider, P.M.; Tidow, N.; Brandt, B.; Buerger, H.; Bulk, E.; et al. MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 2003, 22, 8031-8041.
    • (2003) Oncogene , vol.22 , pp. 8031-8041
    • Ji, P.1    Diederichs, S.2    Wang, W.3    Böing, S.4    Metzger, R.5    Schneider, P.M.6    Tidow, N.7    Brandt, B.8    Buerger, H.9    Bulk, E.10
  • 82
    • 33847185603 scopus 로고    scopus 로고
    • A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains
    • Hutchinson, J.N.; Ensminger, A.W.; Clemson, C.M.; Lynch, C.R.; Lawrence, J.B.; Chess, A. A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics 2007, 8, e39.
    • (2007) BMC Genomics , vol.8
    • Hutchinson, J.N.1    Ensminger, A.W.2    Clemson, C.M.3    Lynch, C.R.4    Lawrence, J.B.5    Chess, A.6
  • 84
    • 0026849544 scopus 로고
    • Monoallelic expression of the human H19 gene
    • Zhang, Y.; Tycko, B. Monoallelic expression of the human H19 gene. Nat. Genet. 1992, 1, 40-44.
    • (1992) Nat. Genet. , vol.1 , pp. 40-44
    • Zhang, Y.1    Tycko, B.2
  • 86
    • 84865238694 scopus 로고    scopus 로고
    • Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells
    • Yang, F.; Bi, J.; Xue, X.; Zheng, L.; Zhi, K.; Hua, J. Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cells. FEBS J. 2012, 279, 3159-3165.
    • (2012) FEBS J. , vol.279 , pp. 3159-3165
    • Yang, F.1    Bi, J.2    Xue, X.3    Zheng, L.4    Zhi, K.5    Hua, J.6
  • 90
    • 77950881915 scopus 로고    scopus 로고
    • Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer
    • Tsang, W.P.; Ng, E.K.O.; Ng, S.S.M.; Jin, H.; Yu, J.; Sung, J.J.Y.; Kwok, T.T. Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis 2010, 31, 350-358.
    • (2010) Carcinogenesis , vol.31 , pp. 350-358
    • Tsang, W.P.1    Ng, E.K.O.2    Ng, S.S.M.3    Jin, H.4    Yu, J.5    Sung, J.J.Y.6    Kwok, T.T.7
  • 93
    • 80053633503 scopus 로고    scopus 로고
    • A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript
    • Onyango, P.; Feinberg, A.P. A nucleolar protein, H19 opposite tumor suppressor (HOTS), is a tumor growth inhibitor encoded by a human imprinted H19 antisense transcript. Proc. Natl. Acad. Sci. USA 2011, 108, 16759-16764.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 16759-16764
    • Onyango, P.1    Feinberg, A.P.2
  • 94
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano, M.; Hannon, G.J.; Beach, D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993, 366, 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 96
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19 Arf
    • Kamijo, T.; Zindy, F.; Roussel, M.F.; Quelle, D.E.; Downing, J.R.; Ashmun, R.A.; Grosveld, G.; Sherr, C.J. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19 Arf. Cell 1997, 91, 649-659.
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1    Zindy, F.2    Roussel, M.F.3    Quelle, D.E.4    Downing, J.R.5    Ashmun, R.A.6    Grosveld, G.7    Sherr, C.J.8
  • 98
    • 33747587608 scopus 로고    scopus 로고
    • Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
    • Gil, J.; Peters, G. Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all. Nat. Rev. Mol. Cell Biol. 2006, 7, 667-677.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 667-677
    • Gil, J.1    Peters, G.2
  • 100
    • 77952887426 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new breast cancer susceptibility loci
    • Morrison, J.; Pernet, D.; Renwick, A.; Maranian, M. Genome-wide association study identifies five new breast cancer susceptibility loci. Nat. Genet. 2010, 42, 504-507.
    • (2010) Nat. Genet. , vol.42 , pp. 504-507
    • Morrison, J.1    Pernet, D.2    Renwick, A.3    Maranian, M.4
  • 104
    • 79551623370 scopus 로고    scopus 로고
    • ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS
    • Pasmant, E.; Sabbagh, A.; Vidaud, M.; Bièche, I. ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS. FASEB J. 2011, 25, 444-448.
    • (2011) FASEB J. , vol.25 , pp. 444-448
    • Pasmant, E.1    Sabbagh, A.2    Vidaud, M.3    Bièche, I.4
  • 107
    • 84870479616 scopus 로고    scopus 로고
    • Long non-coding RNA gadd7 interacts with TDP-43 and regulates Cdk6 mRNA decay
    • Liu, X.; Li, D.; Zhang, W.; Guo, M.; Zhan, Q. Long non-coding RNA gadd7 interacts with TDP-43 and regulates Cdk6 mRNA decay. EMBO J. 2012, 31, 4415-4427.
    • (2012) EMBO J. , vol.31 , pp. 4415-4427
    • Liu, X.1    Li, D.2    Zhang, W.3    Guo, M.4    Zhan, Q.5
  • 109
    • 79961170994 scopus 로고    scopus 로고
    • A ceRNA hypothesis: The rosetta stone of a hidden RNA language?
    • Salmena, L.; Poliseno, L.; Tay, Y.; Kats, L.; Pandolfi, P.P. A ceRNA hypothesis: The rosetta stone of a hidden RNA language? Cell 2011, 146, 353-358.
    • (2011) Cell , vol.146 , pp. 353-358
    • Salmena, L.1    Poliseno, L.2    Tay, Y.3    Kats, L.4    Pandolfi, P.P.5
  • 110
    • 79955836034 scopus 로고    scopus 로고
    • Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation
    • Yang, Z.; Zhou, L.; Wu, L.-M.; Lai, M.-C.; Xie, H.-Y.; Zhang, F.; Zheng, S.-S. Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann. Surg. Oncol. 2011, 18, 1243-1250.
    • (2011) Ann. Surg. Oncol. , vol.18 , pp. 1243-1250
    • Yang, Z.1    Zhou, L.2    Wu, L.-M.3    Lai, M.-C.4    Xie, H.-Y.5    Zhang, F.6    Zheng, S.-S.7
  • 112
    • 84867862596 scopus 로고    scopus 로고
    • Evaluation of novel gene UCA1 as a tumor biomarker for the detection of bladder cancer
    • Zhang, Z.; Hao, H.; Zhang, C.-J.; Yang, X.-Y.; He, Q.; Lin, J. Evaluation of novel gene UCA1 as a tumor biomarker for the detection of bladder cancer. Zhonghua Yi Xue Za Zhi 2012, 92, 384-387.
    • (2012) Zhonghua Yi Xue Za Zhi , vol.92 , pp. 384-387
    • Zhang, Z.1    Hao, H.2    Zhang, C.-J.3    Yang, X.-Y.4    He, Q.5    Lin, J.6
  • 113
    • 84872825450 scopus 로고    scopus 로고
    • Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation
    • Lai, M.-C.; Yang, Z.; Zhou, L.; Zhu, Q.-Q.; Xie, H.-Y.; Zhang, F.; Wu, L.-M.; Chen, L.-M.; Zheng, S.-S. Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation. Med. Oncol. 2012, 29, 1810-1816.
    • (2012) Med. Oncol. , vol.29 , pp. 1810-1816
    • Lai, M.-C.1    Yang, Z.2    Zhou, L.3    Zhu, Q.-Q.4    Xie, H.-Y.5    Zhang, F.6    Wu, L.-M.7    Chen, L.-M.8    Zheng, S.-S.9
  • 114
    • 84880652927 scopus 로고    scopus 로고
    • Targeting long non-coding RNA to therapeutically upregulate gene expression
    • Wahlestedt, C. Targeting long non-coding RNA to therapeutically upregulate gene expression. Nat. Rev. Drug Discov. 2013, 12, 433-446.
    • (2013) Nat. Rev. Drug Discov. , vol.12 , pp. 433-446
    • Wahlestedt, C.1
  • 115
    • 84873626217 scopus 로고    scopus 로고
    • Long non-coding RNA targeting and transcriptional de-repression
    • Weinberg, M.S.; Morris, K.V. Long non-coding RNA targeting and transcriptional de-repression. Nucleic Acid Ther. 2013, 23, 9-13.
    • (2013) Nucleic Acid Ther , vol.23 , pp. 9-13
    • Weinberg, M.S.1    Morris, K.V.2
  • 116
    • 84883249501 scopus 로고    scopus 로고
    • Canonical and non-canonical barriers facing antimiR cancer therapeutics
    • Cheng, C.J.; Saltzman, W.M.; Slack, F.J. Canonical and non-canonical barriers facing antimiR cancer therapeutics. Curr. Med. Chem. 2013, 20, 3582-3593.
    • (2013) Curr. Med. Chem. , vol.20 , pp. 3582-3593
    • Cheng, C.J.1    Saltzman, W.M.2    Slack, F.J.3
  • 118
    • 81855224576 scopus 로고    scopus 로고
    • MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy
    • Kasinski, A.L.; Slack, F.J. MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 2011, 11, 849-864.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 119
    • 83255186696 scopus 로고    scopus 로고
    • MicroRNA therapeutics
    • Broderick, J.A.; Zamore, P.D. MicroRNA therapeutics. Gene Ther. 2011, 18, 1104-1110.
    • (2011) Gene Ther. , vol.18 , pp. 1104-1110
    • Broderick, J.A.1    Zamore, P.D.2
  • 121
    • 72249122539 scopus 로고    scopus 로고
    • Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: Targeting the RNAs that cause myotonic muscular dystrophy
    • Lee, M.M.; Childs-Disney, J.L.; Pushechnikov, A.; French, J.M.; Sobczak, K.; Thornton, C.A.; Disney, M.D. Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: Targeting the RNAs that cause myotonic muscular dystrophy. J. Am. Chem. Soc. 2009, 131, 17464-17472.
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 17464-17472
    • Lee, M.M.1    Childs-Disney, J.L.2    Pushechnikov, A.3    French, J.M.4    Sobczak, K.5    Thornton, C.A.6    Disney, M.D.7
  • 122
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto, D.; Rossi, J.J. The promises and pitfalls of RNA-interference-based therapeutics. Nature 2009, 457, 426-433.
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2


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