Organization of the mouse and human DC network

Current Opinion in Immunology

Volumn 26, Issue 1, 2014, Pages 90-99

  Schlitzer, Andreas ^a   Ginhoux, Florent ^a  

^a AGENCY FOR SCIENCE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD11B ANTIGEN; CD123 ANTIGEN; CD135 ANTIGEN; CD14 ANTIGEN; CD1C ANTIGEN; CD64 ANTIGEN; CD8ALPHA ANTIGEN; DECTIN 1; DECTIN 2; GAMMA INTERFERON; GLYCOPROTEIN P 15095; INHIBITOR OF DIFFERENTIATION 2; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NOTCH2 RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

BACTERIAL IMMUNITY; CELL SPECIFICITY; CYTOKINE RELEASE; DENDRITIC CELL; FUNGUS IMMUNITY; HUMAN; INFLAMMATION; INFLAMMATORY DENDRITIC CELL; LANGERHANS CELL; MUCOSAL IMMUNITY; NONHUMAN; ONTOGENY; PARASITE IMMUNITY; PLASMACYTOID DENDRITIC CELL; PROTEIN EXPRESSION; REVIEW; TH17 CELL; TH2 CELL; TUMOR IMMUNITY; VIRUS IMMUNITY;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD1; ANTIGENS, CD11B; ANTIGENS, CD8; ANTIGENS, SURFACE; CELL POLARITY; CROSS-PRIMING; DENDRITIC CELLS; GLYCOPROTEINS; HUMANS; IMMUNITY, CELLULAR; INFLAMMATION; INTEGRIN ALPHA CHAINS; MICE; TH17 CELLS;

EID: 84889687682     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2013.11.002     Document Type: Review

References (107)

1. Merad M., Sathe P., Helft J., Miller J., Mortha A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu Rev Immunol 2013, 31:563-604.
2. Varol C., Vallon-Eberhard A., Elinav E., Aychek T., Shapira Y., Luche H., Fehling H.J., Hardt W.D., Shakhar G., Jung S. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity 2009, 31:502-512.
3. Bogunovic M., Ginhoux F., Helft J., Shang L., Hashimoto D., Greter M., Liu K., Jakubzick C., Ingersoll M.A., Leboeuf M., et al. Origin of the lamina propria dendritic cell network. Immunity 2009, 31:513-525.
4. Merad M., Ginhoux F., Collin M. Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol 2008, 8:935-947.
5. Serbina N.V., Pamer E.G. Coordinating innate immune cells to optimize microbial killing. Immunity 2008, 29:672-674.
6. MacDonald K.P., Munster D.J., Clark G.J., Dzionek A., Schmitz J., Hart D.N. Characterization of human blood dendritic cell subsets. Blood 2002, 100:4512-4520.
7. Ziegler-Heitbrock L., Ancuta P., Crowe S., Dalod M., Grau V., Hart D.N., Leenen P.J., Liu Y.J., MacPherson G., Randolph G.J., et al. Nomenclature of monocytes and dendritic cells in blood. Blood 2010, 116:e74-e80.
8. Nestle F.O., Zheng X.G., Thompson C.B., Turka L.A., Nickoloff B.J. Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets. J Immunol 1993, 151:6535-6545.
9. Harman A.N., Bye C.R., Nasr N., Sandgren K.J., Kim M., Mercier S.K., Botting R.A., Lewin S.R., Cunningham A.L., Cameron P.U. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. J Immunol 2013, 190:66-79.
10. Geissmann F., Manz M.G., Jung S., Sieweke M.H., Merad M., Ley K. Development of monocytes, macrophages, and dendritic cells. Science 2010, 327:656-661.
11. Hoeffel G., Wang Y., Greter M., See P., Teo P., Malleret B., Leboeuf M., Low D., Oller G., Almeida F., et al. Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med 2012, 209:1167-1181.
12. Satpathy A.T., Kc W., Albring J.C., Edelson B.T., Kretzer N.M., Bhattacharya D., Murphy T.L., Murphy K.M. Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med 2012, 209:1135-1152.
13. Meredith M.M., Liu K., Darrasse-Jeze G., Kamphorst A.O., Schreiber H.A., Guermonprez P., Idoyaga J., Cheong C., Yao K.H., Niec R.E., et al. Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. J Exp Med 2012, 209:1153-1165.
14. Schraml B.U., van Blijswijk J., Zelenay S., Whitney P.G., Filby A., Acton S.E., Rogers N.C., Moncaut N., Carvajal J.J., Reis Sousa C. Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage. Cell 2013, 154:843-858.
15. + DCs. J Exp Med 2009, 206:3115-3130.
16. + conventional dendritic cells. J Exp Med 2010, 207:823-836.
17. + dendritic cells in cytotoxic T cell immunity. Science 2008, 322:1097-1100.
18. Mashayekhi M., Sandau M.M., Dunay I.R., Frickel E.M., Khan A., Goldszmid R.S., Sher A., Ploegh H.L., Murphy T.L., Sibley L.D., et al. CD8alpha(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites. Immunity 2011, 35:249-259.
19. Torti N., Walton S.M., Murphy K.M., Oxenius A. Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation. Eur J Immunol 2011, 41:2612-2618.
20. + dendritic cells. Nat Immunol 2009, 10:488-495.
21. + pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen. J Exp Med 2011, 208:1789-1797.
22. Ahrens S., Zelenay S., Sancho D., Hanc P., Kjaer S., Feest C., Fletcher G., Durkin C., Postigo A., Skehel M., et al. F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells. Immunity 2012, 36:635-645.
23. Sancho D., Joffre O.P., Keller A.M., Rogers N.C., Martinez D., Hernanz-Falcon P., Rosewell I., Reis Sousa C. Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 2009, 458:899-903.
24. Zelenay S., Keller A.M., Whitney P.G., Schraml B.U., Deddouche S., Rogers N.C., Schulz O., Sancho D., Reis Sousa C. The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice. J Clin Invest 2012, 122:1615-1627.
25. + dendritic cells are protected from influenza virus infection. J Clin Invest 2012, 122:4037-4047.
26. Annacker O., Coombes J.L., Malmstrom V., Uhlig H.H., Bourne T., Johansson-Lindbom B., Agace W.W., Parker C.M., Powrie F. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J Exp Med 2005, 202:1051-1061.
27. + dendritic cells display unique functional properties that are conserved between mice and humans. J Exp Med 2008, 205:2139-2149.
28. + regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 2007, 204:1757-1764.
29. + dendritic cells. Eur J Immunol 2010, 40:1877-1883.
30. + DCs are major producers of IFN-lambda in response to poly IC. J Exp Med 2010, 207:2703-2717.
31. Lewis K.L., Caton M.L., Bogunovic M., Greter M., Grajkowska L.T., Ng D., Klinakis A., Charo I.F., Jung S., Gommerman J.L., et al. Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity 2011, 35:780-791.
32. + dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 2013, 38:970-983.
33. Plantinga M., Guilliams M., Vanheerswynghels M., Deswarte K., Branco-Madeira F., Toussaint W., Vanhoutte L., Neyt K., Killeen N., Malissen B., et al. Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 2013, 38:322-335.
34. Persson E.K., Uronen-Hansson H., Semmrich M., Rivollier A., Hagerbrand K., Marsal J., Gudjonsson S., Hakansson U., Reizis B., Kotarsky K., et al. IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation. Immunity 2013, 38:958-969.
35. Tamoutounour S., Henri S., Lelouard H., de Bovis B., de Haar C., van der Woude C.J., Woltman A.M., Reyal Y., Bonnet D., Sichien D., et al. CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. Eur J Immunol 2012, 42:3150-3166.
36. Kabashima K., Banks T.A., Ansel K.M., Lu T.T., Ware C.F., Cyster J.G. Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cells. Immunity 2005, 22:439-450.
37. + dendritic cells. Immunity 1998, 9:839-847.
38. Satpathy A.T., Briseno C.G., Lee J.S., Ng D., Manieri N.A., Kc W., Wu X., Thomas S.R., Lee W.L., Turkoz M., et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol 2013, 14:937-948.
39. Dudziak D., Kamphorst A.O., Heidkamp G.F., Buchholz V.R., Trumpfheller C., Yamazaki S., Cheong C., Liu K., Lee H.W., Park C.G., et al. Differential antigen processing by dendritic cell subsets in vivo. Science 2007, 315:107-111.
40. Wakim L.M., Waithman J., van Rooijen N., Heath W.R., Carbone F.R. Dendritic cell-induced memory T cell activation in nonlymphoid tissues. Science 2008, 319:198-202.
41. Kinnebrew M.A., Buffie C.G., Diehl G.E., Zenewicz L.A., Leiner I., Hohl T.M., Flavell R.A., Littman D.R. Pamer EG: Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity 2012, 36:276-287.
42. Martin J.C., Beriou G., Heslan M., Chauvin C., Utriainen L., Aumeunier A., Scott C.L., Mowat A., Cerovic V., Houston S.A., et al. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol 2013.
43. Cerovic V., Houston S.A., Scott C.L., Aumeunier A., Yrlid U., Mowat A.M., Milling S.W. Intestinal CD103(-) dendritic cells migrate in lymph and prime effector T cells. Mucosal Immunol 2013, 6:104-113.
44. Cisse B., Caton M.L., Lehner M., Maeda T., Scheu S., Locksley R., Holmberg D., Zweier C., den Hollander N.S., Kant S.G., et al. Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development. Cell 2008, 135:37-48.
45. Albanesi C., Scarponi C., Pallotta S., Daniele R., Bosisio D., Madonna S., Fortugno P., Gonzalvo-Feo S., Franssen J.D., Parmentier M., et al. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J Exp Med 2009, 206:249-258.
46. Nestle F.O., Conrad C., Tun-Kyi A., Homey B., Gombert M., Boyman O., Burg G., Liu Y.J., Gilliet M. Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med 2005, 202:135-143.
47. Asselin-Paturel C., Boonstra A., Dalod M., Durand I., Yessaad N., Dezutter-Dambuyant C., Vicari A., O'Garra A., Biron C., Briere F., et al. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat Immunol 2001, 2:1144-1150.
48. Bjorck P. Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice. Blood 2001, 98:3520-3526.
49. Nakano H., Yanagita M., Gunn M.D. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med 2001, 194:1171-1178.
50. Mouries J., Moron G., Schlecht G., Escriou N., Dadaglio G., Leclerc C. Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. Blood 2008, 112:3713-3722.
51. Young L.J., Wilson N.S., Schnorrer P., Proietto A., ten Broeke T., Matsuki Y., Mount A.M., Belz G.T., O'Keeffe M., Ohmura-Hoshino M., et al. Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells. Nat Immunol 2008, 9:1244-1252.
52. Ginhoux F., Merad M. Ontogeny and homeostasis of Langerhans cells. Immunol Cell Biol 2010, 88:387-392.
53. Merad M., Manz M.G., Karsunky H., Wagers A., Peters W., Charo I., Weissman I.L., Cyster J.G., Engleman E.G. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol 2002, 3:1135-1141.
54. Sere K., Baek J.H., Ober-Blobaum J., Muller-Newen G., Tacke F., Yokota Y., Zenke M., Hieronymus T. Two distinct types of Langerhans cells populate the skin during steady state and inflammation. Immunity 2012, 37:905-916.
55. Fainaru O., Woolf E., Lotem J., Yarmus M., Brenner O., Goldenberg D., Negreanu V., Bernstein Y., Levanon D., Jung S., et al. Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation. EMBO J 2004, 23:969-979.
56. Flacher V., Tripp C.H., Stoitzner P., Haid B., Ebner S., Del Frari B., Koch F., Park C.G., Steinman R.M., Idoyaga J., et al. Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. J Invest Dermatol 2010, 130:755-762.
57. Romani N., Koide S., Crowley M., Witmer-Pack M., Livingstone A.M., Fathman C.G., Inaba K., Steinman R.M. Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells. J Exp Med 1989, 169:1169-1178.
58. Nakajima S., Igyarto B.Z., Honda T., Egawa G., Otsuka A., Hara-Chikuma M., Watanabe N., Ziegler S.F., Tomura M., Inaba K., et al. Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling. J Allergy Clin Immunol 2012, 129:1048-1055. e1046.
59. Igyarto B.Z., Haley K., Ortner D., Bobr A., Gerami-Nejad M., Edelson B.T., Zurawski S.M., Malissen B., Zurawski G., Berman J., et al. Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity 2011, 35:260-272.
60. Leon B., Lopez-Bravo M., Ardavin C. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 2007, 26:519-531.
61. Serbina N.V., Salazar-Mather T.P., Biron C.A., Kuziel W.A., Pamer E.G. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 2003, 19:59-70.
62. Greter M., Helft J., Chow A., Hashimoto D., Mortha A., Agudo-Cantero J., Bogunovic M., Gautier E.L., Miller J., Leboeuf M., et al. GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity 2012, 36:1031-1046.
63. Nakano H., Lin K.L., Yanagita M., Charbonneau C., Cook D.N., Kakiuchi T., Gunn M.D. Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses. Nat Immunol 2009, 10:394-402.
64. Hohl T.M., Rivera A., Lipuma L., Gallegos A., Shi C., Mack M., Pamer E.G. Inflammatory monocytes facilitate adaptive CD4T cell responses during respiratory fungal infection. Cell Host Microb 2009, 6:470-481.
65. Mochizuki K., Xie F., He S., Tong Q., Liu Y., Mochizuki I., Guo Y., Kato K., Yagita H., Mineishi S., et al. Delta-like ligand 4 identifies a previously uncharacterized population of inflammatory dendritic cells that plays important roles in eliciting allogeneic T cell responses in mice. J Immunol 2013, 190:3772-3782.
66. Cheong C., Matos I., Choi J.H., Dandamudi D.B., Shrestha E., Longhi M.P., Jeffrey K.L., Anthony R.M., Kluger C., Nchinda G., et al. Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell 2010, 143:416-429.
67. + nonlymphoid dendritic cells. Immunity 2012, 37:60-73.
68. Poulin L.F., Reyal Y., Uronen-Hansson H., Schraml B.U., Sancho D., Murphy K.M., Hakansson U.K., Moita L.F., Agace W.W., Bonnet D., et al. DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues. Blood 2012, 119:6052-6062.
69. Mittag D., Proietto A.I., Loudovaris T., Mannering S.I., Vremec D., Shortman K., Wu L., Harrison L.C. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol 2011, 186:6207-6217.
70. Segura E., Durand M., Amigorena S. Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells. J Exp Med 2013, 210:1035-1047.
71. Caminschi I., Proietto A.I., Ahmet F., Kitsoulis S., Shin Teh J., Lo J.C., Rizzitelli A., Wu L., Vremec D., van Dommelen S.L., et al. The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement. Blood 2008, 112:3264-3273.
72. + dendritic cells and a subset of monocytes. J Biol Chem 2008, 283:16693-16701.
73. + T cells. Immunity 2009, 31:823-833.
74. + dendritic cells. J Exp Med 2010, 207:1283-1292.
75. Crozat K., Guiton R., Guilliams M., Henri S., Baranek T., Schwartz-Cornil I., Malissen B., Dalod M. Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets. Immunol Rev 2010, 234:177-198.
76. + dendritic cells. J Exp Med 2010, 207:1261-1271.
77. + dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med 2010, 207:1247-1260.
78. Schulz O., Diebold S.S., Chen M., Naslund T.I., Nolte M.A., Alexopoulou L., Azuma Y.T., Flavell R.A., Liljestrom P., Reis Sousa C. Toll-like receptor 3 promotes cross-priming to virus-infected cells. Nature 2005, 433:887-892.
79. + dendritic cells. J Exp Med 2010, 207:1273-1281.
80. Yoshio S., Kanto T., Kuroda S., Matsubara T., Higashitani K., Kakita N., Ishida H., Hiramatsu N., Nagano H., Sugiyama M., et al. Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-lambda in response to hepatitis C virus. Hepatology 2013, 57:1705-1715.
81. Dzionek A., Fuchs A., Schmidt P., Cremer S., Zysk M., Miltenyi S., Buck D.W., Schmitz J. BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 2000, 165:6037-6046.
82. Lundberg K., Albrekt A.S., Nelissen I., Santegoets S., de Gruijl T.D., Gibbs S., Lindstedt M. Transcriptional profiling of human dendritic cell populations and models - unique profiles of in vitro dendritic cells and implications on functionality and applicability. PLoS One 2013, 8:e52875.
83. + T cell responses elicited by different subsets of human skin migratory dendritic cells. J Immunol 2005, 175:7905-7915.
84. + mucosal effector T cells via the cytokine TGF-beta. Immunity 2013, 38:818-830.
85. + dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation. J Exp Med 2012, 209:935-945.
86. Haniffa M., Ginhoux F., Wang X.N., Bigley V., Abel M., Dimmick I., Bullock S., Grisotto M., Booth T., Taub P., et al. Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation. J Exp Med 2009, 206:371-385.
87. Angel C.E., Chen C.J., Horlacher O.C., Winkler S., John T., Browning J., MacGregor D., Cebon J., Dunbar P.R. Distinctive localization of antigen-presenting cells in human lymph nodes. Blood 2009, 113:1257-1267.
88. + antigen-presenting cells in human dermis respond rapidly to CCR7 ligands. J Immunol 2006, 176:5730-5734.
89. + dermal dendritic cells. Immunity 2008, 29:497-510.
90. + dendritic cells triggered by dual TLR ligation. J Immunol 2012, 189:5729-5744.
91. Jakubzick C., Gautier E.L., Gibbings S.L., Sojka D.K., Schlitzer A., Johnson T.E., Ivanov S., Duan Q., Bala S., Condon T., et al. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes 2013, 39(3):599-610.
92. Gilliet M., Conrad C., Geiges M., Cozzio A., Thurlimann W., Burg G., Nestle F.O., Dummer R. Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch Dermatol 2004, 140:1490-1495.
93. Siegal F.P., Kadowaki N., Shodell M., Fitzgerald-Bocarsly P.A., Shah K., Ho S., Antonenko S., Liu Y.J. The nature of the principal type 1 interferon-producing cells in human blood. Science 1999, 284:1835-1837.
94. Perussia B., Fanning V., Trinchieri G. A leukocyte subset bearing HLA-DR antigens is responsible for in vitro alpha interferon production in response to viruses. Nat Immun Cell Growth Regul 1985, 4:120-137.
95. Stone A.E., Giugliano S., Schnell G., Cheng L., Leahy K.F., Golden-Mason L., Gale M., Rosen H.R. Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells. PLoS Pathog 2013, 9:e1003316.
96. Grouard G., Rissoan M.C., Filgueira L., Durand I., Banchereau J., Liu Y.J. The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J Exp Med 1997, 185:1101-1111.
97. Rissoan M.C., Soumelis V., Kadowaki N., Grouard G., Briere F., de Waal Malefyt R., Liu Y.J. Reciprocal control of T helper cell and dendritic cell differentiation. Science 1999, 283:1183-1186.
98. Hoeffel G., Ripoche A.C., Matheoud D., Nascimbeni M., Escriou N., Lebon P., Heshmati F., Guillet J.G., Gannage M., Caillat-Zucman S., et al. Antigen crosspresentation by human plasmacytoid dendritic cells. Immunity 2007, 27:481-492.
99. Kanitakis J., Morelon E., Petruzzo P., Badet L., Dubernard J.M. Self-renewal capacity of human epidermal Langerhans cells: observations made on a composite tissue allograft. Exp Dermatol 2011, 20:145-146.
100. Kanitakis J., Petruzzo P., Dubernard J.M. Turnover of epidermal Langerhans' cells. N Engl J Med 2004, 351:2661-2662.
101. Bauer T., Zagorska A., Jurkin J., Yasmin N., Koffel R., Richter S., Gesslbauer B., Lemke G., Strobl H. Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med 2012, 209:2033-2047.
102. + hemopoietic progenitors. J Immunol 1996, 157:1499-1507.
103. Seneschal J., Clark R.A., Gehad A., Baecher-Allan C.M., Kupper T.S. Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells. Immunity 2012, 36:873-884.
104. Hansel A., Gunther C., Ingwersen J., Starke J., Schmitz M., Bachmann M., Meurer M., Rieber E.P., Schakel K. Human slan (6-sulfo LacNAc) dendritic cells are inflammatory dermal dendritic cells in psoriasis and drive strong TH17/TH1 T-cell responses. J Allergy Clin Immunol 2011, 127:787-794. e781-e790.
105. Lowes M.A., Chamian F., Abello M.V., Fuentes-Duculan J., Lin S.L., Nussbaum R., Novitskaya I., Carbonaro H., Cardinale I., Kikuchi T., et al. Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). Proc Natl Acad Sci U S A 2005, 102:19057-19062.
106. Segura E., Touzot M., Bohineust A., Cappuccio A., Chiocchia G., Hosmalin A., Dalod M., Soumelis V., Amigorena S. Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity 2013, 38:336-348.
107. Wilsmann-Theis D., Koch S., Mindnich C., Bonness S., Schnautz S., von Bubnoff D., Bieber T. Generation and functional analysis of human TNF-alpha/iNOS-producing dendritic cells (Tip-DC). Allergy 2013, 68:890-898.