Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: New evidence for a gene-environment interaction

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 150, Issue 5, 2009, Pages 660-669

  Bet, Pierre M ^a,b   Penninx, Brenda W J H ^a   Bochdanovits, Zoltan ^a,b   Uitterlinden, André G ^c   Beekman, Aartjan T F ^a   Van Schoor, Natasja M ^a   Deeg, Dorly J H ^a   Hoogendijk, Witte J G ^a,b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Childhood adversity; Depression; Depressive symptoms; Glucocorticoid receptor gene; HPA axis

Indexed keywords

BINDING PROTEIN; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE BINDING GLOBULIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; CHILDHOOD; CONTROLLED STUDY; DEPRESSION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MAJOR CLINICAL STUDY; MALE; MENTAL STRESS; PRIORITY JOURNAL; RECURRENT DISEASE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT SURVIVORS OF CHILD ABUSE; AGED; AGED, 80 AND OVER; DEPRESSION; DISEASE SUSCEPTIBILITY; ENVIRONMENT; EPISTASIS, GENETIC; FEMALE; GENE FREQUENCY; HUMANS; LIFE CHANGE EVENTS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, GLUCOCORTICOID; STRESS, PSYCHOLOGICAL;

EID: 67649440703     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30886     Document Type: Article

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