The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eating

Journal of Psychiatric Research

Volumn 43, Issue 16, 2009, Pages 1278-1286

  Racine, Sarah E ^a   Culbert, Kristen M ^a   Larson, Christine L ^b   Klump, Kelly L ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

Binge eating; Dietary restraint; Gene environment interactions; Impulsivity; Serotonin

Indexed keywords

DNA; SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER;

ADULT; ALLELE; ARTICLE; BINGE EATING DISORDER; CONTROLLED STUDY; DIET RESTRICTION; ENVIRONMENTAL FACTOR; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HEALTH SURVEY; HUMAN; IMPULSIVENESS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; QUANTITATIVE TRAIT; QUESTIONNAIRE; SALIVA ANALYSIS; SCORING SYSTEM;

EID: 70449526560     PISSN: 00223956     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2009.05.002     Document Type: Article

References (88)

1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Text revision. Washington, DC: American Psychiatric Association; 2000.
2. Aubert R., Betoulle D., Herbeth B., Siest G., and Fumeron F. 5-ht 2a receptor gene polymorphism is associated with food and alcohol intake in obese people. International Journal of Obesity 24 (2000) 920-924
3. Bell L., and Newns K. What is multi-impulsive bulimia and can multi-impulsive patients benefit from supervised self-help?. European Eating Disorders Review 10 (2002) 413-427
4. Benjamin J., Li L., Patterson C., Greenberg B.D., Murphy D.L., and Hamer D.H. Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nature Genetics 12 (1996) 81-84
5. Blundell J.E. Serotonin and the biology of feeding. American Journal of Clinical Nutrition 55 (1992) 155S-159S
6. Bruce K.R., Steiger H., Joober R., Ng Ying Kin N.M.K., Israel M., and Young S.N. Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. American Journal of Medical Genetics 137B (2005) 40-44
7. Bulik C.M., Sullivan P.F., and Kendler K.S. Heritability of binge-eating and broadly defined bulimia nervosa. Biological Psychiatry 44 (1998) 1210-1218
8. Burt S.A. Genes and popularity: evidence of an evocative gene-environment correlation. Psychological Science 19 (2008) 112-113
9. Cardon L.R., and Bell J.I. Association study designs for complex diseases. Nature Reviews Genetics 2 (2001) 91-99
10. Caspi A., Moffitt T.E., Cannon M., McClay J., Murray R., Harrington H.L., et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-o-methyltransferase gene: longitudinal evidence of a gene × environment interaction. Biological Psychiatry 57 (2005) 1117-1127
11. Culbert K.M., Slane J.D., and Klump K.L. Genetics of eating disorders. In: Wonderlich S., Mitchell J., de Zwann M., and Steiger H. (Eds). Eating disorders review: Part 3 (2008), Radcliffe Publishing Ltd., Oxford 27-42
12. Deaver C.M., Miltenberger R.G., Symth J., Meidinger A., and Crosby R. An evaluation of affect and binge eating. Behavior Modification 27 (2003) 578-599
13. Di Bella D., Catalano M., Cavallini M.C., Riboldi C., and Bellodi L. Serotonin transporter linked polymorphic region in anorexia and bulimia nervosa. Molecular Psychiatry 5 (2000) 233-241
14. Diaz-Marsa M., Carrasco J.L., and Saiz J. A study of temperament and personality in anorexia nervosa and bulimia nervosa. Journal of Personality Disorders 14 (2000) 352-359
15. Enoch M.S., Kaye W.H., Rotondo A., Greenberg B.D., Murphy D.L., and Goldman D. 5-HT2A promoter polymorphism -1438G/A, anorexia nervosa, and obsessive-compulsive disorder. Lancet 351 (1998) 1785-1786
16. Fairburn C.G., and Beglin S.J. Assessment of eating disorders: interview or self-report questionnaire?. International Journal of Eating Disorders 16 (1994) 363-370
17. Aiken L.S., and West S.G. Multiple regression: testing and interpreting interactions (1991), Sage Publications, Newbury Park
18. Fairburn CG, Cooper P. The eating disorder examination. 12th ed. In: Fairburn C., Wilson G., editors. Binge eating: nature, assessment and treatment. New York: Guilford Press; 1993.
19. Fischer S., Smith G.T., and Anderson K.G. Clarifying the role of impulsivity in bulimia nervosa. International Journal of Eating Disorders 33 (2003) 406-411
20. Fitzgibbon M.L., Spring B., Avellone M.E., Blackman L.R., Pingitore R., and Stolley M.R. Correlates of binge eating in Hispanic, Black, and White women. International Journal of Eating Disorders 24 (1998) 43-52
21. Fuentes J.A., Lauzurica N., Hurtado A., Escarti A., Barrios V., Morande G., et al. Analysis of the -1438 G/A polymorphism of the 5-HT2A serotonin receptor gene in bulimia nervosa patients with or without a history of anorexia nervosa. Psychiatric Genetics 14 (2000) 107-109
22. Fumeron F., Betoulle D., Aubert R., Herbeth B., Siest G., and Rigaud D. Association of a functional 5-ht transporter gene polymorphism with anorexia nervosa and food intake. Molecular Psychiatry 6 (2001) 9-10
23. Hashimoto K., Koizumi H., Nakazato M., Shimizu E., and Iyo M. Role of brain-derived neurotrophic factor in eating disorders: recent findings and its pathophysiological implications. Progress in Neuro-Psychopharmacology and Biological Psychiatry 29 (2005) 499-504
24. Hattersley A.T., and McCarthy M.I. What makes a good genetic association study?. The Lancet 366 (2005) 1315-1323
25. Heils A., Teufel A., Petri S., Stober G., Riederer P., Bengel D., et al. Allelic variation of human serotonin transporter gene expression. Journal of Neurochemistry 66 (1996) 2621-2624
26. Jacobi C., Hayward C., de Zwaan M., Kraemer H.C., and Agras W.S. Coming to terms with risk factors for eating disorders: application of risk terminology and suggestions for a general taxonomy. Psychological Bulletin 130 (2004) 19-65
27. Jimerson D.C., Lesem M.D., Kaye W.H., and Brewerton T.D. Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes. Archives of General Psychiatry 49 (1992) 132-138
28. Kaye W.H., Bailer U.F., Frank G., Wagner A., and Henry S.E. Brain imaging of serotonin after recovery from anorexia and bulimia nervosa. Physiology and Behavior 86 (2005) 15-17
29. Klump K.L., and Culbert K.M. Molecular genetic studies of eating disorders. Current Directions in Psychological Science 16 (2007) 37-41
30. Klump K.L., McGue M., and Iacono W.G. Age differences in genetic and environmental influences on eating attitudes and behaviors in preadolescent and adolescent female twins. Journal of Abnormal Psychology 109 (2000) 239-251
31. Klump KL, Suisman J, Burt SA, McGue M, Iacono WG. Genetic and environmental influences on eating disorder symptoms: an adoption study, submitted for publication.
32. Kraemer H.C., Stice E., Kazdin A., Offord D., and Kupfer D. How do risk factors work together? Mediators, moderators, and independent, overlapping, and proxy risk factors. American Journal of Psychiatry 158 (2001) 848-856
33. Laucht M., Skowronek M.H., Becker K., Schmidt M.H., Esser G., Schulze T.G., et al. Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample. Archives of General Psychiatry 64 (2007) 585-590
34. Lauzurica N., Hurtado A., Escarti A., Delgado M., Barrios V., Morandé G., et al. Polymorphisms within the promoter and the intron 2 of the serotonin transporter gene in a population of bulimic patients. Neuroscience Letters 352 (2003) 226-230
35. Lebrun B., Bariohay B., Moyse E., and Jean A. Brain-derived neurotrophic factor (BDNF) and food intake regulation: a minireview. Autonomic Neuroscience 126-127 (2006) 30-38
36. Leibowitz S.F., and Alexander J.T. Hypothalamic serotonin in control of eating behavior, meal size, and body weight. Biological Psychiatry 44 (1998) 851-864
37. Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274 (1996) 1527-1531
38. Levitan R.D., Kaplan A.S., Joffe R.T., Levitt A.J., and Brown G.M. Hormonal and subjective responses to intravenous meta-chlorophenylpiperazine in bulimia nervosa. Archives of General Psychiatry 54 (1997) 521-527
39. Loehlin J.C. Genes and environment in personality development (1992), Sage Publications, Newbury Park
40. Luce K.H., and Crowther J.H. The reliability of the eating disorder examination-self report questionnaire version (EDE-Q). International Journal of Eating Disorders 25 (1999) 349-351
41. McManus F., and Waller G.I. A functional analysis of binge-eating. Clinical Psychology Review 15 (1995) 845-863
42. Moffitt T.E., Caspi A., and Rutter M. Strategy for investigating interactions between measured genes and measured environments. Archives of General Psychiatry 62 (2005) 473-481
43. Monteleone P., Brambilla F., Bortolotti F., Ferraro C., and Maj M. Plasma prolactin response to d-fenfluramine is blunted in bulimic patients with frequent binge episodes. Psychological Medicine 28 (1998) 975-983
44. Monteleone P., Santonastaso P., Mauri M., Bellodi L., Erzegovesi S., Fuschino A., et al. Investigation of the serotonin transporter regulatory region polymorphism in bulimia nervosa: a relationship to harm avoidance, nutritional parameters, and psychiatric comorbidity. Psychosomatic Medicine 68 (2006) 99-103
45. Monteleone P., Tortorella A., Castaldo E., and Maj M. Association of a functional serotonin transporter gene polymorphism with binge eating disorder. American Journal of Medical Genetics 141B (2006) 7-9
46. Monteleone P., Zanardini R., Tortorella A., Gennarelli M., Castaldo E., Canestrelli B., et al. The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder. Neuroscience Letters 406 (2006) 133-137
47. Nacmias B., Ricca V., Tedde A., Mezzani B., Rotella C.M., and Sorbi S. 5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa. Neuroscience Letters 277 (1999) 134-136
48. Neumark-Sztainer D., Falkner N., Story M., Perry C., Hannan P.J., and Mulert S. Weight-teasing among adolescents: correlations with weight status and disordered eating behaviors. International Journal of Obesity 26 (2002) 123-131
49. Nishiguchi N., Matsushita S., Suzuki K., Murayama M., Shirakawa O., and Higuchi S. Association between 5HT2A receptor gene promoter region polymorphism and eating disorders in Japanese patients. Biological Psychiatry 50 (2001) 123-128
50. Nomura M., Kusumi I., Kaneko M., Masui T., Daiguji M., Ueno T., et al. Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior. Psychopharmacology 188 (2006) 129
51. Osborne JW, Costello AB. Best practices in exploratory factor analysis: four recommendations for getting the most from your analysis. Practical Assessment Research & Evaluation 2005; 10.
52. Ottman R. Gene-environment interaction: definitions and study design. Preventive Medicine 25 (1996) 764-770
53. Paaver M., Nordquist N., Parik J., Harro M., Oreland L., and Harro J. Platelet MAO activity and the 5-HTT gene promoter polymorphism are associated with impulsivity and cognitive style in visual information processing. Psychopharmacology 194 (2007) 545-554
54. Parsons M.J., D'Souza U.M., Arranz M., Kerwin R.W., and Makoff A.J. The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity. Biological Psychiatry 56 (2004) 406-410
55. Patton J.H., Stanford M.S., and Barratt E. Factor structure of the Barratt Impulsiveness Scale. Journal of Clinical Psychology 31 (1995) 609-774
56. Pike K.M., Dohm F.A., Striegel-Moore R.H., Wifley D.D., and Fairburn C.G. A comparison of black and white women with binge eating disorder. American Journal of Psychiatry 158 (2001) 1455-1460
57. Placidi R.J., Chandler P.C., Oswald K.D., Maldonado C., Wauford P.K., and Boggiano M.M. Stress and hunger alter the anorectic efficacy of fluoxetine in binge-eating rats with a history of caloric restriction. International Journal of Eating Disorders 36 (2004) 328-341
58. Plomin R., DeFries J.C., and McClearn G.E. Behavioral genetics: a primer (1990), Freeman, New York
59. Polivy J., and Herman C.P. Dieting and binging: a causal analysis. American Psychologist 40 (1985) 193-201
60. Prado-Lima P.S., Cruz I.B.M., Schwanke C.H.A., Netto C.A., and Licinio J. Human food preferences are associated with a 5-ht2a serotonergic receptor polymorphism. Molecular Psychiatry 11 (2006) 889-891
61. Reichborn-Kjennerud T., Bulik C.M., Tambs K., and Harris J.R. Genetic and environmental influences on binge eating in the absence of compensatory behaviors: a population-based twin study. International Journal of Eating Disorders 36 (2004) 307-314
62. Ribases M., Fernandez-Aranda F., Gratacos M., Mercader J.M., Casasnovas C., Nunez A., et al. Contribution of the serotongergic system to anxious and depressive traits that may be partially responsible for the phenotypical variability of bulimia nervosa. Journal of Psychiatric Research 42 (2008) 50-57
63. Ribases M., Gratacos M., Fernandez-Aranda F., Bellodi L., Boni C., and Anderluh M.B. Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations. European Journal of Human Genetics 13 (2005) 428-434
64. Ricca V., Nacmias B., Boldrini M., Cellini E., di Bernardo M., Ravaldi C., et al. Psychopathological traits and 5-HT2A receptor promoter polymorphism (-1438 G/A) in patients suffering from anorexia nervosa and bulimia nervosa. Neuroscience Letters 365 (2004) 92-96
65. Ricca V., Nacmias B., Cellini E., Di Bernardo M., Rotella M., and Sorbi S. 5-HT2a receptor gene polymorphism and eating disorders. Neuroscience Letters 323 (2002) 105-108
66. Rosval L., Steiger H., Bruce K., Israel M., Richardson J., and Aubut M. Impulsivity in women with eating disorders: problem of response inhibition, planning, or attention?. International Journal of Eating Disorders 39 (2006) 590
67. Sakado K., Sakado M., Muratake T., Mundt C., and Someya T. A psychometrically derived impulsive trait related to a polymorphism in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) in a Japanese nonclinical population: assessment by the Barratt Impulsiveness Scale (BIS). American Journal of Medical Genetics 121B (2003) 71-75
68. Schinka J.A., Letsch E.A., and Crawford F.C. DRD4 and novelty seeking: results of meta-analyses. American Journal of Medical Genetics 114B (2002) 643-648
69. Shinohara M., Mizushima H., Hirano M., Shioe K., Nakazawa M., Hiejima Y., et al. Eating disorders with binge-eating behavior are associated with the s allele of the 3'-UTR VNTR polymorphism of the dopamine transporter gene. Journal of Psychiatry and Neuroscience 29 (2004) 134-137
70. Spurlock G., Heils A., Holmans P., Williams J., D'Souza U.M., Cardno A., et al. A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter. Molecular Psychiatry 3 (1998) 42-49
71. Steiger H. Eating disorders and the serotonin connection: state, trait and developmental effects. Journal of Psychiatric Neuroscience 29 (2004) 20-29
72. Steiger H., and Bruce K.R. Phenotypes, endophenotypes, and genotypes in bulimia spectrum eating disorders. The Canadian Journal of Psychiatry 52 (2007) 220-227
73. Steiger H., Gauvin L., Joober R., Israel M., Ng Ying Kin N.M.K., Bruce K.R., et al. Intrafamilial correspondences on platelet [3H-] paroxetine-binding indices in bulimic probands and their unaffected first-degree relatives. Neuropsychopharmacology 31 (2006) 1785-1792
74. Steiger H., Joober R., Israel M., Young S.N., Ng Ying Kin N.M.K., Gauvin L., et al. The 5HTTLPR polymorphism, psychopathologic symptoms, and platelet [3H-] paroxetine binding in bulimic symptoms. International Journal of Eating Disorders 37 (2005) 57-60
75. Steiger H., Leonard S., Ng Ying Kin N.M.K., Ladouceur C., Ramdoyal D., and Young S.N. Childhood abuse and platelet tritiated paroxetine binding in bulimia nervosa: implications for borderline personality disorder. Journal of Clinical Psychiatry 61 (2000) 428-435
76. Stewart T.M., Williamson D.A., and White M.A. Rigid vs. flexible dieting: association with eating disorder symptoms in non-obese women. Appetite 38 (2002) 39-44
77. Stice E., and Agras W.S. Predicting onset and cessation of bulimic behaviors during adolescence. a longitudinal grouping analysis. Behavior Therapy 29 (1998) 257-276
78. Stice E., Cooper J.A., Schoeller D.A., Tappe K., and Lowe M.R. Are dietary restraint scales valid measures of moderate-to long-term dietary restriction? Objective biological and behavioral data suggest not. Psychological Assessment 19 (2007) 449
79. Stice E., Fisher M., and Lowe M.R. Are dietary restraint scales valid measures of acute dietary restriction? unobtrusive observational data suggest not. Psychological Assessment 16 (2004) 51-59
80. Stice E., Spangler D., and Agras W.S. Exposure to media-portrayed thin-ideal images adverse affects vulnerable girls: a longitudinal experiment. Journal of Social and Clinical Psychology 20 (2001) 270-288
81. Sundgot-Borgen J., and Torstveit M.K. Prevalence of eating disorders in elite athletes is higher than in the general population. Clinical Journal of Sports Medicine 14 (2004) 25-32
82. Tellegen A., Lykken D.T., Bouchard T., Wilcox K.J., Segal N.L., and Rich S. Personality similarity in twins reared apart and together. Journal of Personality and Social Psychology 54 (1988) 1031-1039
83. van Strien T., Frijters J.E., Van Staveren W.A., Defares P.B., and Deurenberg P. The predictive validity of the Dutch Restrained Eating Scale. International Journal of Eating Disorders 5 (1986) 747-755
84. von Ranson K.M., Klump K.L., Iacono W.G., and McGue M. The Minnesota Eating Behavior Survey: a brief measure of disordered eating attitudes and behaviors. Eating Behaviors 6 (2005) 373-392
85. Wardle J. Eating style: a validation of the Dutch Eating Behavior Questionnaire in normal subjects and women with eating disorders. Journal of Psychosomatic Research 31 (1987) 161-169
86. Westen D., and Harnden-Fischer J. Personality profiles in eating disorders: rethinking the distinction between Axis I and Axis II. American Journal of Psychiatry 158 (2001) 547-562
87. Wonderlich S.A., Crosby R.D., Joiner T., Peterson C.B., Bardone-Cone A., Klein M., et al. Personality subtyping and bulimia nervosa: psychopathological and genetic correlates. Psychological Medicine 35 (2005) 649-657
88. Ziegler A., Hebebrand J., Gorg T., Rosenkranz K., Fichter M., and Dahlmann B. Further lack of association between 5-HT2A gene promoter polymorphisms and susceptibility to eating disorders and a meta-analysis pertaining to anorexia nervosa. Molecular Psychiatry 4 (1999) 410-412