Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover

PLoS Biology

Volumn 11, Issue 11, 2013, Pages

  Huang, Shoujun ^a   Zhang, Zhao ^b   Zhang, Chunxia ^c   Lv, Xiangdong ^b   Zheng, Xiudeng ^a,c   Chen, Zhenping ^a   Sun, Liwei ^c   Wang, Hailong ^a   Zhu, Yuanxiang ^a   Zhang, Jing ^c   Yang, Shuyan ^a   Lu, Yi ^b   Sun, Qinmiao ^c   Tao, Yi ^a   Liu, Feng ^c   Zhao, Yun ^b   Chen, Dahua ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN PATCHED; SMOOTHENED PROTEIN; SMURF PROTEIN; SONIC HEDGEHOG PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; MATHEMATICAL MODEL; NONHUMAN; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; CELL LINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENZYME ACTIVATION; HEDGEHOG PROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; WING; ZEBRAFISH;

EID: 84889044006     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001721     Document Type: Article

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