Morin reduces hepatic inflammation-associated lipid accumulation in high fructose-fed rats via inhibiting sphingosine kinase 1/sphingosine 1-phosphate signaling pathway

Biochemical Pharmacology

Volumn 86, Issue 12, 2013, Pages 1791-1804

  Wang, Xing ^a   Zhang, Dong Mei ^a   Gu, Ting Ting ^a   Ding, Xiao Qin ^a   Fan, Chen Yu ^a   Zhu, Qin ^a   Shi, Yun Wei ^a   Hong, Ye ^a   Kong, Ling Dong ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Hepatic inflammation; Lipid accumulation; Morin; NF B; SphK1 S1P signaling pathway

Indexed keywords

FRUCTOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN; LIPID; MORIN; PIOGLITAZONE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; SPHINGOSINE KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARBOHYDRATE DIET; FLAVONOID; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG BLOOD LEVEL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HYPERLIPIDEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; LIPID LIVER LEVEL; LIPID STORAGE; LIVER INJURY; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ADMINISTRATION AND DOSAGE; ANALOGS AND DERIVATIVES; ANIMAL; CARBOHYDRATE DIET; DRUG EFFECTS; INFLAMMATION; LIPID METABOLISM; LIVER; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; DIETARY CARBOHYDRATES; FLAVONOIDS; FRUCTOSE; INFLAMMATION; LIPID METABOLISM; LIVER; LYSOPHOSPHOLIPIDS; MALE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 84888875869     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.10.005     Document Type: Article

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