Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol-induced myocardial infarction in rats

Journal of Natural Medicines

Volumn 66, Issue 1, 2012, Pages 95-101

  Al Numair, Khalid S ^a   Chandramohan, Govindasamy ^a   Alsaif, Mohammed A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Glycoproteins; Isoproterenol; Membrane bound enzymes; Morin; Myocardial infarction

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (MAGNESIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; CREATINE KINASE MB; FUCOSE; GLYCOPROTEIN; HEXOSAMINE; HEXOSE; ISOPRENALINE; LACTATE DEHYDROGENASE; MORIN; SIALIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HEART INFARCTION; MALE; NONHUMAN; RAT; TREATMENT DURATION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BIOLOGICAL MARKERS; DISEASE MODELS, ANIMAL; FLAVONOIDS; GLYCOPROTEINS; ISOPROTERENOL; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; PROTECTIVE AGENTS; RATS; RATS, WISTAR;

EID: 84856226251     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0558-2     Document Type: Article

References (28)

1. Bloom S, Cancilla PA (1969) Myocytolysis and mitochondrial calcification in rat myocardium after low doses of isoproterenol. Am J Pathol 54:373-391
2. Rona G (1985) Catecholamine cardiotoxicity. J Mol Cell Cardiol 17:291-306 (Pubitemid 15030720)
3. Sesso HD, Gaziano JM, Liu S, Buring JE (2003) Flavonoid intake and the risk of cardiovascular disease in women. Am J Clin Nutr 77:1400-1408 (Pubitemid 39655272)
4. Fang SH, Hou YC, Chang WC, Hsiu SL, Chao PDL, Chiang BL (2003) Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci 74:743-756
5. Wu TW, Zeng LH, Wu J, Fung KP (1993) Morin hydrate is a plant-derived and antioxidant-based hepatoprotector. Life Sci 53:PL213-PL218
6. Kitagawa S, Sakamoto H, Tano H (2004) Inhibitory effects of flavonoids on free radical-induced hemolysis and their oxidative effects on hemoglobin. Chem Pharm Bull 52:999-1001 (Pubitemid 41701883)
7. Brown J, O'Prey J, Harrison PR (2003) Enhanced sensitivity of human oral tumours to the flavonol, morin, during cancer progression: involvement of the Akt and stress kinase pathways. Carcinogenesis 24:171-177 (Pubitemid 36267083)
8. Nandave M, Ojha SK, Joshi S, Kumari S, Arya DS (2009) Moringa oleifera leaf extract prevents isoproterenol-induced myocardial damage in rats: evidence for an antioxidant, antiperoxidative, and cardioprotective intervention. J Med Food 12:47-55
9. Okinaka S, Kumagai H, Ebashi S, Sugita H, Momoi H, Toyokura Y, Fujie Y (1961) Serum creatine phosphokinase. Activity in progressive muscular dystrophy and neuromuscular diseases. Arch Neurol 4:520-525
10. Fiske CH, Subbarow Y (1925) The colorimetric determination of phosphorus. J Biol Chem 66:375-400
11. Dubois M, Gilles KA (1956) Methods in enzymology. Academic Press, New York, p 83
12. Wagner WD (1979) A more sensitive assay discriminating galactosamine and glucosamine in mixtures. Anal Biochem 94:394-396 (Pubitemid 9173030)
13. Dische Z, Shettles LB (1948) A specific color reaction of methylpentoses and a spectrophotometric micromethod for their determination. J Biol Chem 175:595-604
14. Warren L (1959) Thiobarbituric acid assay of sialic acid. J Biol Chem 234:1971-1975
15. Bonting SL (1970) Membrane and ion transport. Wiley Interscience, London, p 257
16. Hjertén S, Pan H (1983) Purification and characterization of two forms of a low-affinity Ca2?-ATPase from erythrocyte membranes. Biochim Biophys Acta 728:281-288 (Pubitemid 13133546)
17. Ohnishi T, Suzuki T, Suzuki Y, Ozawa K (1982) A comparative study of plasma membrane Mg2?-ATPase activities in normal, regenerating and malignant cells. Biochim Biophys Acta 684:67-74 (Pubitemid 12186244)
18. Sumitra M, Manikandan P, Kumar DA, Arutselvan N, Balakrishna K, Manohar BM, Puvanakrishnan R (2001) Experimental myocardial necrosis in rats: role of arjunolic acid on platelet aggregation, coagulation and antioxidant status. Mol Cell Biochem 224:135-142 (Pubitemid 32962659)
19. Ahmed KK, Rana AC, Dixit VK (2004) Effect of Calotropis procera latex on isoproterenol induced myocardial infarction in albino rats. Phytomedicine 11:327-330 (Pubitemid 38657463)
20. Kang DG, Moon MK, Sohn EJ, Lee DH, Lee HS (2004) Effects of morin on blood pressure and metabolic changes in fructoseinduced hypertensive rats. Biol Pharm Bull 27:1779-1783 (Pubitemid 41701603)
21. Subash S, Subramanian P (2009) Morin a flavonoid exerts antioxidant potential in chronic hyperammonemic rats: a biochemical and histopathological study. Mol Cell Biochem 327:153-161
22. Flaherty JT, Weisfeldt ML (1988) Reperfusion injury. Free Radic Biol Med 5:409-419 (Pubitemid 19024292)
23. Ithayarasi AP, Devi CS (1997) Effect of a-tocopherol on lipid peroxidation in isoproterenol induced myocardial infarction in rats. Indian J Physiol Pharmacol 41:369-376 (Pubitemid 27507825)
24. Crook MA, Earle K, Morocutti A, Yip J, Viberti G, Pickup JC (1994) Serum sialic acid, a risk factor for cardiovascular disease, is increased in IDDM patients with microalbuminuria and clinical proteinuria. Diabetes Care 17:305-310 (Pubitemid 24123411)
25. Mathew S, Menon PV, Kurup PA (1982) Changes in glycoproteins in isoproterenol-induced myocardial infarction in rats. Indian J Biochem Biophys 19:41-43 (Pubitemid 12010940)
26. Padmanabhan M, Rajadurai M, Stanely Mainzen Prince P (2008) Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats. Basic Clin Pharmacol Toxicol 103:507-513
27. Karthik Kumar V, Vennila S, Nalini N (2010) Inhibitory effect of morin on DMH-induced biochemical changes and aberrant crypt foci formation in experimental colon carcinogenesis. Environ Toxicol Pharmacol 29:150-157
28. Sreedharan V, Venkatachalam KK, Namasivayam N (2009) Effect of morin on tissue lipid peroxidation and antioxidant status in 1,2-dimethylhydrazine induced experimental colon carcinogenesis. Invest New Drugs 27:21-30