Assessment of the cytotoxic, genotoxic, and antigenotoxic potential of Pycnogenol® in in vitro mammalian cells

Food and Chemical Toxicology

Volumn 61, Issue , 2013, Pages 203-208

  Taner, Gökçe ^a   Aydin, Sevtap ^b   Aytaç, Zeki ^a   Başaran, Arif Ahmet ^b   Başaran, Nurşen ^b  

^a GAZI UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Alkaline comet assay; Cytokinesis block micronucleus assay; Neutral red uptake assay; Pycnogenol ; Trolox equivalent antioxidant capacity

Indexed keywords

CELL DNA; HYDROGEN PEROXIDE; PYCNOGENOL; TROLOX C;

ANIMAL CELL; ANTIGENOTOXIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CHO CELL; CHROMOSOME BREAKAGE; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINESIS; DNA DAMAGE; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG SCREENING; GENOTOXICITY; HUMAN; HUMAN CELL; IC 50; MAMMAL CELL; MICRONUCLEUS TEST; NONHUMAN; PERIPHERAL LYMPHOCYTE;

CRICETULUS GRISEUS; MAMMALIA; PINUS PINASTER;

ALKALINE COMET ASSAY; CYTOKINESIS-BLOCK MICRONUCLEUS ASSAY; NEUTRAL RED UPTAKE ASSAY; PYCNOGENOL®; TROLOX EQUIVALENT ANTIOXIDANT CAPACITY;

ADULT; ANIMALS; ANTIOXIDANTS; CHO CELLS; COMET ASSAY; CRICETINAE; CRICETULUS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; FLAVONOIDS; HUMANS; HYDROGEN PEROXIDE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; PROTECTIVE AGENTS;

EID: 84888828375     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.06.053     Document Type: Article

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