Pycnogenol protects DNA against oxidative damage in vivo

Phytotherapy Research

Volumn 19, Issue 3, 2005, Pages 262-

  Rohdewald, P ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DNA; PLASMID DNA; PYCNOGENOL;

ANTIOXIDANT ACTIVITY; DNA DAMAGE; DRUG EFFICACY; HUMAN; LETTER; LIVER MICROSOME; MICRONUCLEUS TEST; NONHUMAN; OXIDATIVE STRESS;

ANTIOXIDANTS; DNA; FLAVONOIDS; HUMANS; PHYTOTHERAPY;

EID: 20444495261     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1677     Document Type: Letter

References (6)

1. Devaraj S, Vega-López S, Kaul N, Schönlau F, Rohdewald P, Jialal I. 2002. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 37: 931-934.
2. Durackova Z, Trebaticky B, Novotny V, Zitnanova A, Breza J. 2003. Lipid metabolism and erectile function improvement by Pycnogenol®, extract from the bark of Pinus pinaster in patients suffering from erectile dysfunction - a pilot study. Nutr Res 23: 1189-1198.
3. Durackova Z, Muchova J, Sivonova M, Chovanova Z, Hauserova M, Blazicek P, Trebaticka J, Rohdewald P. 2004. Oxidative stress in pathophysiology of attention deficit hyperactivity disorder and its influence by a polyphenolic natural extract, Pycnogenol®. In Polyphenols Communications 2004, Hoikkala A, Soidinsalo O, (eds). Gummerus Printing: Jyväskylä, 177-178.
4. Grosse Düweler K, Rohdewald P. 2000. Urinary metabolites of French maritime pine bark extract in humans. Pharmazie 55: 364-368.
5. Nelson AB, Lau BHS, Ide N, Rong Y. 1998. Pycnogenol inhibits macrophage oxidative burst, lipoprotein oxidation and hydroxyl radical-induced DNA damage. Drug Dev Ind Pharm 24: 139-144.
6. Rohdewald P. 2002. A review of the French maritime pine bark extract (Pycnogenol®), a herbal medication with a diverse pharmacology. Int J Clin Pharmacol Ther 40: 158-168.