Preparation and optimization of triptolide-loaded solid lipid nanoparticles for oral delivery with reduced gastric irritation

Molecules

Volumn 18, Issue 11, 2013, Pages 13340-13356

  Zhang, Cong ^a   Gu, Conghui ^a   Peng, Fan ^a   Liu, Wei ^a   Wan, Jiangling ^a   Xu, Huibi ^a,b   Lam, Christopher Waikei ^b   Yang, Xiangliang ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

Author keywords

Central composite design; Gastric irritation; Microemulsion technique; Solid lipid nanoparticles; Sustained release; Triptolide

Indexed keywords

DITERPENE; EPOXIDE; LIPID; NANOPARTICLE; PHENANTHRENE DERIVATIVE; TRIPTOLIDE;

ANIMAL; ARTICLE; CHEMISTRY; DRUG EFFECT; MALE; RAT; SPRAGUE DAWLEY RAT; STOMACH MUCOSA;

ANIMALS; DITERPENES; EPOXY COMPOUNDS; GASTRIC MUCOSA; LIPIDS; MALE; NANOPARTICLES; PHENANTHRENES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84888625561     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules181113340     Document Type: Article

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