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Volumn 379, Issue 2, 2009, Pages 260-265

The gastrointestinal stability of lipid nanocapsules

Author keywords

Gastrointestinal tract; Lipid nanocapsules; Paclitaxel; Simulated media; Stability

Indexed keywords

LIPID NANOCAPSULE; NANOCAPSULE; PACLITAXEL; PANCREATIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

EID: 68949218775     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.05.069     Document Type: Article
Times cited : (90)

References (43)
  • 1
    • 49749113964 scopus 로고    scopus 로고
    • Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas
    • Allard E., Passirani C., Garcion E., Pigeon P., Vessieres A., Jaouen G., and Benoit J.P. Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas. J. Control. Release 130 (2008) 146-153
    • (2008) J. Control. Release , vol.130 , pp. 146-153
    • Allard, E.1    Passirani, C.2    Garcion, E.3    Pigeon, P.4    Vessieres, A.5    Jaouen, G.6    Benoit, J.P.7
  • 2
    • 4243460412 scopus 로고
    • On the mechanism of pancreatic lipolysis of glycerides
    • Borgström B. On the mechanism of pancreatic lipolysis of glycerides. Biochim. Biophys. Acta 13 (1954) 491-504
    • (1954) Biochim. Biophys. Acta , vol.13 , pp. 491-504
    • Borgström, B.1
  • 3
    • 43449084030 scopus 로고    scopus 로고
    • Polymeric micelles in oral chemotherapy
    • Bromberg L. Polymeric micelles in oral chemotherapy. J. Control. Release 128 (2008) 99-112
    • (2008) J. Control. Release , vol.128 , pp. 99-112
    • Bromberg, L.1
  • 4
    • 0029562489 scopus 로고
    • Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects
    • Constantinides P.P. Lipid microemulsions for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects. Pharm. Res. 12 (1995) 1561-1572
    • (1995) Pharm. Res. , vol.12 , pp. 1561-1572
    • Constantinides, P.P.1
  • 7
    • 0031913402 scopus 로고    scopus 로고
    • Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms
    • Dressman J.B., Amidon G.L., Reppas C., and Shah V.P. Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms. Pharm. Res. 15 (1998) 11-22
    • (1998) Pharm. Res. , vol.15 , pp. 11-22
    • Dressman, J.B.1    Amidon, G.L.2    Reppas, C.3    Shah, V.P.4
  • 8
    • 0343907176 scopus 로고    scopus 로고
    • Structure and function of gastro-intestinal lipases
    • Embleton J.K., and Pouton C.W. Structure and function of gastro-intestinal lipases. Adv. Drug Deliv. Rev. 25 (1997) 15-32
    • (1997) Adv. Drug Deliv. Rev. , vol.25 , pp. 15-32
    • Embleton, J.K.1    Pouton, C.W.2
  • 9
    • 0031750861 scopus 로고    scopus 로고
    • Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs
    • Galia E., Nicolaides E., Horter D., Lobenberg R., Reppas C., and Dressman J.B. Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs. Pharm. Res. 15 (1998) 698-705
    • (1998) Pharm. Res. , vol.15 , pp. 698-705
    • Galia, E.1    Nicolaides, E.2    Horter, D.3    Lobenberg, R.4    Reppas, C.5    Dressman, J.B.6
  • 10
    • 0344012523 scopus 로고    scopus 로고
    • Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability
    • Gao P., Rush B.D., Pfund W.P., Huang T., Bauer J.M., Morozowich W., Kuo M.S., and Hageman M.J. Development of a supersaturable SEDDS (S-SEDDS) formulation of paclitaxel with improved oral bioavailability. J. Pharm. Sci. 92 (2003) 2386-2398
    • (2003) J. Pharm. Sci. , vol.92 , pp. 2386-2398
    • Gao, P.1    Rush, B.D.2    Pfund, W.P.3    Huang, T.4    Bauer, J.M.5    Morozowich, W.6    Kuo, M.S.7    Hageman, M.J.8
  • 11
    • 0037296404 scopus 로고    scopus 로고
    • Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules
    • García-Fuentes M., Torres D., and Alonso M.J. Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules. Colloids Surf. B: Biointerfaces 27 (2003) 159-168
    • (2003) Colloids Surf. B: Biointerfaces , vol.27 , pp. 159-168
    • García-Fuentes, M.1    Torres, D.2    Alonso, M.J.3
  • 12
    • 33748313404 scopus 로고    scopus 로고
    • A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats
    • Garcion E., Lamprecht A., Heurtault B., Paillard A., Aubert-Pouessel A., Denizot B., Menei P., and Benoit J.P. A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats. Mol. Cancer Ther. 5 (2006) 1710-1722
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1710-1722
    • Garcion, E.1    Lamprecht, A.2    Heurtault, B.3    Paillard, A.4    Aubert-Pouessel, A.5    Denizot, B.6    Menei, P.7    Benoit, J.P.8
  • 13
    • 0036297426 scopus 로고    scopus 로고
    • A novel phase inversion-based process for the preparation of lipid nanocarriers
    • Heurtault B., Saulnier P., Pech B., Proust J.E., and Benoit J.P. A novel phase inversion-based process for the preparation of lipid nanocarriers. Pharm. Res. 19 (2002) 875-880
    • (2002) Pharm. Res. , vol.19 , pp. 875-880
    • Heurtault, B.1    Saulnier, P.2    Pech, B.3    Proust, J.E.4    Benoit, J.P.5
  • 14
    • 0035292910 scopus 로고    scopus 로고
    • Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract
    • Horter D., and Dressman J.B. Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract. Adv. Drug Deliv. Rev. 46 (2001) 75-87
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , pp. 75-87
    • Horter, D.1    Dressman, J.B.2
  • 15
    • 43249097007 scopus 로고    scopus 로고
    • Designing biorelevant dissolution tests for lipid formulations: case example-lipid suspension of RZ-50
    • Jantratid E., Janssen N., Chokshi H., Tang K., and Dressman J.B. Designing biorelevant dissolution tests for lipid formulations: case example-lipid suspension of RZ-50. Eur. J. Pharm. Biopharm. 69 (2008) 776-785
    • (2008) Eur. J. Pharm. Biopharm. , vol.69 , pp. 776-785
    • Jantratid, E.1    Janssen, N.2    Chokshi, H.3    Tang, K.4    Dressman, J.B.5
  • 16
    • 44749087279 scopus 로고    scopus 로고
    • Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update
    • Jantratid E., Janssen N., Reppas C., and Dressman J.B. Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update. Pharm. Res. 25 (2008) 1663-1676
    • (2008) Pharm. Res. , vol.25 , pp. 1663-1676
    • Jantratid, E.1    Janssen, N.2    Reppas, C.3    Dressman, J.B.4
  • 17
    • 32244434196 scopus 로고    scopus 로고
    • Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies
    • Kalantzi L., Goumas K., Kalioras V., Abrahamsson B., Dressman J.B., and Reppas C. Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies. Pharm. Res. 23 (2006) 165-176
    • (2006) Pharm. Res. , vol.23 , pp. 165-176
    • Kalantzi, L.1    Goumas, K.2    Kalioras, V.3    Abrahamsson, B.4    Dressman, J.B.5    Reppas, C.6
  • 18
    • 2342557118 scopus 로고    scopus 로고
    • Media to simulate the postprandial stomach. I. Matching the physicochemical characteristics of standard breakfasts
    • Klein S., Butler J., Hempenstall J.M., Reppas C., and Dressman J.B. Media to simulate the postprandial stomach. I. Matching the physicochemical characteristics of standard breakfasts. J. Pharm. Pharmacol. 56 (2004) 605-610
    • (2004) J. Pharm. Pharmacol. , vol.56 , pp. 605-610
    • Klein, S.1    Butler, J.2    Hempenstall, J.M.3    Reppas, C.4    Dressman, J.B.5
  • 19
    • 57149095631 scopus 로고    scopus 로고
    • Drug absorption modeling as a tool to define the strategy in clinical formulation development
    • Kuentz M. Drug absorption modeling as a tool to define the strategy in clinical formulation development. AAPS J. 10 (2008) 473-479
    • (2008) AAPS J. , vol.10 , pp. 473-479
    • Kuentz, M.1
  • 20
    • 33646124502 scopus 로고    scopus 로고
    • Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition
    • Lamprecht A., and Benoit J.P. Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition. J. Control. Release 112 (2006) 208-213
    • (2006) J. Control. Release , vol.112 , pp. 208-213
    • Lamprecht, A.1    Benoit, J.P.2
  • 21
    • 0030131048 scopus 로고    scopus 로고
    • Degradation of poly(d,l-lactic acid) nanoparticles coated with albumin in model digestive fluids (USP XXII)
    • Landry F.B., Bazile D.V., Spenlehauer G., Veillard M., and Kreuter J. Degradation of poly(d,l-lactic acid) nanoparticles coated with albumin in model digestive fluids (USP XXII). Biomaterials 17 (1996) 715-723
    • (1996) Biomaterials , vol.17 , pp. 715-723
    • Landry, F.B.1    Bazile, D.V.2    Spenlehauer, G.3    Veillard, M.4    Kreuter, J.5
  • 22
    • 0030927353 scopus 로고    scopus 로고
    • Characterization of fluids from the stomach and proximal jejunum in men and women
    • Lindahl A., Ungell A.L., Knutson L., and Lennernas H. Characterization of fluids from the stomach and proximal jejunum in men and women. Pharm. Res. 14 (1997) 497-502
    • (1997) Pharm. Res. , vol.14 , pp. 497-502
    • Lindahl, A.1    Ungell, A.L.2    Knutson, L.3    Lennernas, H.4
  • 23
    • 0032844618 scopus 로고    scopus 로고
    • Setting bioequivalence requirements for drug development based on preclinical data: optimizing oral drug delivery systems
    • Lipka E., and Amidon G.L. Setting bioequivalence requirements for drug development based on preclinical data: optimizing oral drug delivery systems. J. Control. Release 62 (1999) 41-49
    • (1999) J. Control. Release , vol.62 , pp. 41-49
    • Lipka, E.1    Amidon, G.L.2
  • 24
    • 0034080127 scopus 로고    scopus 로고
    • Dissolution testing as a prognostic tool for oral drug absorption: dissolution behavior of glibenclamide
    • Lobenberg R., Kramer J., Shah V.P., Amidon G.L., and Dressman J.B. Dissolution testing as a prognostic tool for oral drug absorption: dissolution behavior of glibenclamide. Pharm. Res. 17 (2000) 439-444
    • (2000) Pharm. Res. , vol.17 , pp. 439-444
    • Lobenberg, R.1    Kramer, J.2    Shah, V.P.3    Amidon, G.L.4    Dressman, J.B.5
  • 25
    • 0023014049 scopus 로고
    • Transfer of protons from bulk solution to the surface of poly(l-lactide) microcapsules
    • Makino K., Ohshima H., and Kondo T. Transfer of protons from bulk solution to the surface of poly(l-lactide) microcapsules. J. Microencapsul. 3 (1986) 195-202
    • (1986) J. Microencapsul. , vol.3 , pp. 195-202
    • Makino, K.1    Ohshima, H.2    Kondo, T.3
  • 26
    • 43249121029 scopus 로고    scopus 로고
    • Gut instincts: explorations in intestinal physiology and drug delivery
    • McConnell E.L., Fadda H.M., and Basit A.W. Gut instincts: explorations in intestinal physiology and drug delivery. Int. J. Pharm. 364 (2008) 213-226
    • (2008) Int. J. Pharm. , vol.364 , pp. 213-226
    • McConnell, E.L.1    Fadda, H.M.2    Basit, A.W.3
  • 27
    • 0030598260 scopus 로고    scopus 로고
    • Biodegradation of solid lipid nanoparticles as a function of lipase incubation time
    • Müller R.H., Rühl D., and Runge S.A. Biodegradation of solid lipid nanoparticles as a function of lipase incubation time. Int. J. Pharm. 144 (1996) 115-121
    • (1996) Int. J. Pharm. , vol.144 , pp. 115-121
    • Müller, R.H.1    Rühl, D.2    Runge, S.A.3
  • 28
    • 0034948871 scopus 로고    scopus 로고
    • Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration
    • Nicolaides E., Symillides M., Dressman J.B., and Reppas C. Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration. Pharm. Res. 18 (2001) 380-388
    • (2001) Pharm. Res. , vol.18 , pp. 380-388
    • Nicolaides, E.1    Symillides, M.2    Dressman, J.B.3    Reppas, C.4
  • 29
    • 0037177514 scopus 로고    scopus 로고
    • Lipase degradation of Dynasan 114 and 116 solid lipid nanoparticles (SLN)-effect of surfactants, storage time and crystallinity
    • Olbrich C., Kayser O., and Muller R.H. Lipase degradation of Dynasan 114 and 116 solid lipid nanoparticles (SLN)-effect of surfactants, storage time and crystallinity. Int. J. Pharm. 237 (2002) 119-128
    • (2002) Int. J. Pharm. , vol.237 , pp. 119-128
    • Olbrich, C.1    Kayser, O.2    Muller, R.H.3
  • 30
    • 0345148806 scopus 로고    scopus 로고
    • Enzymatic degradation of SLN-effect of surfactant and surfactant mixtures
    • Olbrich C., and Müller R.H. Enzymatic degradation of SLN-effect of surfactant and surfactant mixtures. Int. J. Pharm. 180 (1999) 31-39
    • (1999) Int. J. Pharm. , vol.180 , pp. 31-39
    • Olbrich, C.1    Müller, R.H.2
  • 31
    • 33745386420 scopus 로고    scopus 로고
    • Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded lipid nanocapsules
    • Peltier S., Oger J.M., Lagarce F., Couet W., and Benoit J.P. Enhanced oral paclitaxel bioavailability after administration of paclitaxel-loaded lipid nanocapsules. Pharm. Res. 23 (2006) 1243-1250
    • (2006) Pharm. Res. , vol.23 , pp. 1243-1250
    • Peltier, S.1    Oger, J.M.2    Lagarce, F.3    Couet, W.4    Benoit, J.P.5
  • 32
    • 33847394968 scopus 로고    scopus 로고
    • Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
    • Porter C.J., Trevaskis N.L., and Charman W.N. Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs. Nat Rev. Drug Discov. 6 (2007) 231-248
    • (2007) Nat Rev. Drug Discov. , vol.6 , pp. 231-248
    • Porter, C.J.1    Trevaskis, N.L.2    Charman, W.N.3
  • 33
    • 39149092022 scopus 로고    scopus 로고
    • Enhancing intestinal drug solubilisation using lipid-based delivery systems
    • Porter C.J.H., Pouton C.W., Cuine J.F., and Charman W.N. Enhancing intestinal drug solubilisation using lipid-based delivery systems. Adv. Drug Deliv. Rev. 60 (2008) 673-691
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 673-691
    • Porter, C.J.H.1    Pouton, C.W.2    Cuine, J.F.3    Charman, W.N.4
  • 34
    • 0033805858 scopus 로고    scopus 로고
    • Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems
    • Pouton C.W. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems. Eur. J. Pharm. Sci. 11 Suppl. 2 (2000) S93-S98
    • (2000) Eur. J. Pharm. Sci. , vol.11 , Issue.SUPPL. 2
    • Pouton, C.W.1
  • 35
    • 53649097113 scopus 로고    scopus 로고
    • Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells
    • Sahu A., Bora U., Kasoju N., and Goswami P. Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells. Acta Biomater. 4 (2008) 1752-1761
    • (2008) Acta Biomater. , vol.4 , pp. 1752-1761
    • Sahu, A.1    Bora, U.2    Kasoju, N.3    Goswami, P.4
  • 38
    • 8144225703 scopus 로고    scopus 로고
    • Enhancement of gastrointestinal absorption of poorly water soluble drugs via lipid based systems
    • Subramanian N., and Ghosal S.K. Enhancement of gastrointestinal absorption of poorly water soluble drugs via lipid based systems. Indian J. Exp. Biol. 42 (2004) 1056-1065
    • (2004) Indian J. Exp. Biol. , vol.42 , pp. 1056-1065
    • Subramanian, N.1    Ghosal, S.K.2
  • 39
    • 0343962248 scopus 로고    scopus 로고
    • The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration
    • Tobío M., Sánchez A., Vila A., Soriano I., Evora C., Vila-Jato J.L., and Alonso M.J. The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration. Colloids Surf. B: Biointerfaces 18 (2000) 315-323
    • (2000) Colloids Surf. B: Biointerfaces , vol.18 , pp. 315-323
    • Tobío, M.1    Sánchez, A.2    Vila, A.3    Soriano, I.4    Evora, C.5    Vila-Jato, J.L.6    Alonso, M.J.7
  • 40
    • 42549116239 scopus 로고    scopus 로고
    • Novel drug nanocarriers combining hydrophilic cyclodextrins and chitosan
    • Trapani A., Garcia-Fuentes M., and Alonso M.J. Novel drug nanocarriers combining hydrophilic cyclodextrins and chitosan. Nanotechnology 19 (2008) 1-10
    • (2008) Nanotechnology , vol.19 , pp. 1-10
    • Trapani, A.1    Garcia-Fuentes, M.2    Alonso, M.J.3
  • 41
    • 68949205759 scopus 로고    scopus 로고
    • US.Pharmacopeia.XXIV, 2006. USP 29. Rockville, MD.
    • US.Pharmacopeia.XXIV, 2006. Vol. USP 29. Rockville, MD.
  • 43
    • 33749663431 scopus 로고    scopus 로고
    • Self-assembled nanoparticles of poly(lactide)-vitamin E TPGS copolymers for oral chemotherapy
    • Zhang Z., and Feng S.S. Self-assembled nanoparticles of poly(lactide)-vitamin E TPGS copolymers for oral chemotherapy. Int. J. Pharm. 324 (2006) 191-198
    • (2006) Int. J. Pharm. , vol.324 , pp. 191-198
    • Zhang, Z.1    Feng, S.S.2


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