Hepatoprotective effects of lycopene against carbon tetrachloride-induced acute liver injury in rats

Journal of Functional Foods

Volumn 5, Issue 4, 2013, Pages 1601-1610

  Pinto, Carmen ^a   Rodríguez Galdón, Beatriz ^a   Cestero, Juan J ^a   Macías, Pedro ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

Author keywords

Antioxidants; Liver; Lycopene; Stress oxidative

Indexed keywords

LYCOPERSICON ESCULENTUM; RATTUS;

EID: 84888437541     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2013.07.002     Document Type: Article

References (45)

1. Abete I., Perez Cornago A., Navas-Carretero S., Bondia-Pons I., Zulet M.A., Martinez J.A. A regular lycopene enriched tomato sauce consumption influences antioxidant status of healthy young-subjects: A crossover study. Journal of Functional Foods 2013, 5:28-35.
2. Aebi H. Catalase. Methods of enzymatic analysis 1974, 673-684. Academic Press, New York. U.H. Bergmeyer (Ed.).
3. Ahn T.H., Yang Y.S., Lee J.C., Kim S.H., Jun W., Park S.C., Kim J.C. Ameliorative effects of pycnogenol on carbon tetrachloride-induced hepatic oxidative damage in rats. Phytotherapy Research 2007, 21:1015-1019.
4. Atessian A., Yilmaz S., Karahan I., Ceribasi A.O., Karaoglu A. Effects of lycopene against cisplatin-induced nephrotoxicity and oxidative stress in rats. Toxicology 2005, 212:116-123.
5. Basu S. Carbon tetrachloride-induced lipid peroxidation: eicosanoid formation and their regulation by antioxidant nutrients. Toxicology 2003, 189:113-127.
6. Bandele O.J., Santillo M.F., Ferguson M., Wiesenfel P.L. In vitro toxicity screening of chemical mixtures using HepG2/C3A cells. Food and Chemical Toxicology 2012, 50:1652-1659.
7. Bergmeyer U.H., Holder N. Stimation of GOT activity in serum. Annales de Biologie Clinique 1986, 44:497-501.
8. Bergmeyer U.H., Holder N. Determination of GPT activity in blood. Annales de Biologie Clinique 1986, 44:481-489.
9. Cheeseman K.H., Albano E.F., Thomasi A., Slater T. Biochemical studies on the metabolic activation of halogenated alkanes. Environmental Health Perspectives 1985, 64:85-101.
10. Cuciureanu M., Caruntu I., Paduraru O., Stoica B., Jerca L., Crauciuc E., Nechifor M. The protective effect of montelukast sodium on carbon tetrachloride induced hepatopathy in rat. Prostaglandins and Other Lipid Mediators 2009, 88:82-88.
11. Diaz G., Melis M., Batetta M., Angius F., Balchi A.M. Hydrophobic characterization of intracellular lipids in situ by Nile Red/yellow emission ratio. Micron 2008, 39:819-824.
12. Deng Y., Xu Z., Liu W., Yang H., Xu, Wei Y. Effects of lycopene and proanthocyanidins on hepatotoxicity induced by mercuric chloride in rats. Biological Trace Element Research 2012, 146:213-223.
13. Duque A.L., Pinto M.C., Macias P. Lipoxygenase inhibition by red wine phenolic compounds. Journal of Food Biochemistry 2011, 35:542-555.
14. Ellman G.L. Tissue sulfhydryl groups. Archives of Biochemistry and Biophysics 1959, 82:70-77.
15. Erdman J.W., Ford N.A., Lindshield B.L. Are the health attributes of lycopene related to its antioxidant function?. Archives of Biochemistry and Biophysics 2009, 483:229-235.
16. Hazai E., Bikadi A., Zsila F., Lockwood S.F. Molecular modeling of the non covalent binding of the dietary tomato carotenoids lycopene and lycophyll, and selected oxidative metabolites with 5-lipoxygenase. Bioorganic & Medicinal Chemistry 2006, 14:6859-6867.
17. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases: The first enzymatic step in mercapturic acid formation. Journal of Biological Chemistry 1974, 249:7130-7139.
18. Hazewindus M., Haenen G.R.M.M., Weseler A.R., Bast A. The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and α-tocopherol. Food Chemistry 2012, 132:954-958.
19. Igual M., Garcia-Martinez E., Camacho M.M., Martinez-Navarrete N. Jam processing and storage effects on β-carotene and flavonoids content in grape fruit. Journal of Functional Foods 2013, 5:736-744.
20. Ilahy R., Hdider C., Lenucci M.S., Tlili I., Dalessandro G. Antioxidant activity and bioactive compound changes during fruit ripening of high-lycopene tomato cultivars. Journal of Food Composition and Analysis 2011, 24:588-595.
21. Jia X.Y., Zhang Q.A., Zhang Z.Q., Wang Y., Yuan J.F. Hepatoprotective effects of almond oil against carbon tetrachloride induced liver injury in rats. Food Chemistry 2011, 125:673-678.
22. Kim H. Carotenoids protect cultured rat hepatocytes from injury caused by carbon tetrachloride. International Journal of Biochemistry and Cellular Biology 1995, 27:1303-1309.
23. Kornberg A. Lactic dehydrogenase of muscle. Methods in Enzymology 1955, vol. 1:441-443. Academic Press, New York.
24. Lee B.J., Senevirathne M., Kim J.S., Kim Y.M., Lee M.S., Jeong M.H., Kang Y.M., Kim J.I., Nam B.H., Ahn C.B., Je J.Y. Protective effect of fermented sea tangle against ethanol and carbon tetrachloride-induced hepatic damage in Sprague-Dawley rats. Food and Chemical Toxicology 2010, 48:1123-1128.
25. Marklund S., Marklund G. Involvement of superoxide anion radical in autooxidation of pirogallol as convenient assay for superoxide dismutase. European Journal of Biochemistry 1974, 47:469-474.
26. Monteiro D.A., Almeida J.A., Rantin F.T., Kalinin A.L. Oxidative stress biomarkers in the fresh water characid fish Brycon cephalus, exposed to organophosphorus insecticide Polisuper 600 (methyl parathion). Comparative Biochemistry and Physiology 2006, 143:141-149.
27. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 1979, 95:351-358.
28. Pennathur S., Maitra D., Byun J., Sliskovic I., Abdulhamid I., Saed G.M., Diamond M.P., Abu-Soud H. Potent antioxidative activity of lycopene: A potential role in scavenging hypochlorous acid. Free Radical Biology & Medicine 2010, 49:205-213.
29. Pick E., Keisari Y. A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture. Journal of Immunological Methods 1980, 38:161-170.
30. Pinto M.C., García Barrado J.A., Macias P. Oxidation of resveratrol catalyzed by soybean lipoxygenase. Journal of Agricultural and Food Chemistry 2003, 51:1653-1657.
31. Pinto M.C., Duque A.L., Macias P. Florescence quenching study on the interaction between quercetin and lipoxygenase. Journal of Florescence 2011, 21:1311-1318.
32. Pinto M.C., Duque A.L., Macias P. Fluorescence spectroscopic studies on the interaction of resveratrol with lipoxygenase. Journal of Molecular Structure 2010, 980:143-148.
33. Pinto M.C., Duque A.L., Rodriguez-Galdón B., Cestero J.J., Macias P. Xanthohumol prevents carbon tetrachloride-induced acute liver injury in rats. Food and Chemical Toxicology 2012, 50:3405-3412.
34. Planagun A., Claria J., Miquel R., Lopez-Parra M., Titos E., Masferrer J.L., Arroyo V., Rodes J. The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPAR gamma activation. FASEB Journal 2005, 19:1120-1122.
35. Raja S., Nazeer Ahmaed K.F.H., Kumar V., Mukherjee K., Bandyopadhyay A., Mukherjee P.K. Antioxidant effect of Cytisus scoparius against carbon tetrachloride treated liver injury in rats. Journal of Ethnopharmacology 2007, 109:41-47.
36. Siriamornpurn S., Kaisoon O., Meeso N. Changes in colour, antioxidant activities and carotenoids (lycopene, b carotene, lutein) of marigold flower (Tagetes erecta L.) resulting from different drying processes. Journal of Functional Foods 2012, 4:757-766.
37. Srinivasan M., Devipriya N., Kalpana K.B., Menon V.P. Lycopene: an antioxidant and radioprotector against γ-radiation-induced cellular damages in cultured human lymphocytes. Toxicology 2009, 262:43-49.
38. 4-induced hepatic toxicity in rats. Journal of Agricultural and Food Chemistry 2003, 51:1571-1577.
39. Suryanarayana V.V., Berger A., Sonawane B. The potential metabolomic approaches for investigating mode(s) of action of xenobiotics: case study with carbon tetrachloride. Mutation Research 2011, 722:147-153.
40. Titos E., Ferre N., Lozano J.J., Horrillo R., Lopez-Parra M., Arroyo V., Claria J. Protection from hepatic lipid accumulation and inflammation by genetic ablation of 5-lipoxygenase. Prostaglandins and Other Lipid Mediators 2010, 92:54-61.
41. Ventanas S., Ventanas J., Jurado A., Estevez M. Quality traits in muscle biceps femoris and back-fat from purebred Iberian and reciprocal Iberian×Duroc crossbred pigs. Meat Science 2006, 73:651-659.
42. Wendel A. Glutathione peroxidase. Methods in enzymology 1981, Vol. 77:325-333. Academic Press, London.
43. . Food Chemistry 2002, 77:209-212.
44. Yang D.J., Lin J.T., Chan Y.C., Lin S.C., Lu F.J., Chang T.J., Wang M., Lin H.W., Chang Y.Y. Suppresive effect of carotenoid extract of Dunaliella salina alga on production of LPS-stimulated pro-inflammatory mediators in RAW264.7 cells via NF-κB and JNK inactivation. Journal of Functional Foods 2013, 5:607-615.
45. Yonar M.E., Sakin F. Ameliorative effect of lycopene on antioxidant status in Cyprinus carpio during pyretroid deltamethrin exposure. Pesticide Biochemistry and Physiology 2011, 99:226-231.