Effects of lycopene and proanthocyanidins on hepatotoxicity induced by mercuric chloride in rats

Biological Trace Element Research

Volumn 146, Issue 2, 2012, Pages 213-223

  Deng, Yu ^a   Xu, Zhaofa ^a   Liu, Wei ^a   Yang, Haibo ^a   Xu, Bin ^a   Wei, Yangang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Hepatotoxicity; Lycopene; Mercury; Oxidative stress; Proanthocyanidins

Indexed keywords

ALANINE AMINOTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; LYCOPENE; MALONALDEHYDE; PROANTHOCYANIDIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER HISTOLOGY; LIVER PROTECTION; LIVER STRUCTURE; LIVER TOXICITY; LIVER WEIGHT; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BODY WEIGHT; CAROTENOIDS; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; LIVER; LIVER DISEASES; MALE; MALONDIALDEHYDE; MERCURIC CHLORIDE; MICROSCOPY, ELECTRON, TRANSMISSION; ORGAN SIZE; OXIDATIVE STRESS; PROANTHOCYANIDINS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

RATTUS;

EID: 84862586608     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-011-9242-3     Document Type: Article

References (39)

1. ATSDR (Agency for Toxic Substances and Disease Registry) (1999) Toxicological profile for mercury. US Department of Health and Human Services Public Health Service. Available at http://www.atsdr.cdc.gov/ToxProfiles/tp46. pdf
2. Adams DH, Sonne C, Basu N et al (2010) Mercury contamination in spotted seatrout, Cynoscion nebulosus: an assessment of liver, kidney, blood, and nervous system health. Sci Total Environ 408 (23):5808-5816
3. Goering PL, Morgan DL, Ali SF (2002) Effects of mercury vapor inhalation on reactive oxygen species and antioxidant enzymes in rat brain and kidney are minimal. J Appl Toxicol 22(3):167-172 (Pubitemid 34591515)
4. Dutczak WJ, Ballatori N (1994) Transport of the glutathione-methylmercury complex across liver canalicular membranes on reduced glutathione carriers. J Biol Chem 269(13):9746-9751 (Pubitemid 24196579)
5. Stohs SJ, Bagchi D (1995) Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18(2):321-336
6. McLaughlin JM, Olivo-Marston S, Vitolins MZ et al (2011) Effects of tomato-and soy-rich diets on the IGF-I hormonal network: a crossover study of postmenopausal women at high risk for breast cancer. Cancer Prev Res (Phila) 4(5):702-710
7. Mordente A, Guantario B, Meucci E et al (2011) Lycopene and cardiovascular diseases: an update. CurrMed Chem 18(8):1146-1163
8. Vlajinac H, Ilic M, Marinkovic J et al (2010) Nutrition and prostate cancer. J BUON 15(4):698-703
9. Quilliot D, Forbes A, Dubois F et al (2011) Carotenoid deficiency in chronic pancreatitis: the effect of an increase in tomato consumption. Eur J Clin Nutr 65(2):262-268
10. Mortensen A, Skibsted LH, Sampson J et al (1997) Comparative mechanisms and rates of free radical scavenging by carotenoid antioxidants. FEBS Lett 418(1-2):91-97 (Pubitemid 27514422)
11. Schroeter H, Heiss C, Spencer JP et al (2010) Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs. Mol Aspects Med 31(6):546-557
12. Rossi M, Rosato V, Bosetti C et al (2010) Flavonoids, proanthocyanidins, and the risk of stomach cancer. Cancer Causes Control 21(10):1597-1604
13. Bobe G, Peterson JJ, Gridley G et al (2009) Flavonoid consumption and esophageal cancer among black and white men in the United States. Int J Cancer 125(5):1147-1154
14. Karaaslan O, Ulusoy MG, Kankaya Y et al (2010) Protective effect of grape seed extract against ischaemia/reperfusion injury in a rat epigastricflap model. J Plast Reconstr Aesthet Surg 63 (4):705-710
15. Nichols JA, Katiyar SK (2010) Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms. Arch Dermatol Res 302(2):71-83
16. Yang H, Xu Z, Liu W et al (2011) The protective role of procyanidins and lycopene against mercuric chloride renal damage in rats. Biomed Environ Sci 24(5):56-61
17. Liu W, Xu Z, Yang H et al (2011) The protective effects of tea polyphenols and schisandrin B on nephrotoxicity of mercury. Biol Trace Elem Res (in press)
18. Lowry OH, Rosebrough NJ, Farr AL et al (1951) Protein measurement with folin phenol reagent. J Biol Chem 193:265-275
19. Stockwell PB, Corns WT (1993) The role of atomic fluorescence spectrometry in the automatic environmental monitoring of trace element analysis. J Automatic Chem 15:79-84 (Pubitemid 23299144)
20. Crowley LV (1967) The Reitman-Frankel colorimetric transaminase procedure in suspected myocardial infarction. Clin Chem 13 (6):482-487
21. Weiss TS, Lichtenauer M, Kirchner S et al (2008) Hepatic progenitor cells from adult human livers for cell transplantation. Gut 57(8):1129-1138
22. Li P, Feng XB, Qiu GL et al (2009) Mercury pollution in Asia: a review of the contaminated sites. J Hazard Mater 168(2-3):591-601
23. Nwokocha CR, Owu DU, Ufearo CS et al (2011) Comparative study on the efficacy of Garcinia kola in reducing some heavy metal accumulation in liver of Wistar rats. J Ethnopharmacol 135 (2):488-491
24. Bridges CC, Joshee L, Zalups RK (2011) MRP2 and the handling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury. Toxicol Appl Pharmacol 251(1):50-58
25. Ung CY, Lam SH, Hlaing MM et al (2011) Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation. BMC Genomics 11:212
26. Sener G, Sehirli O, Tozan A et al (2007) Ginkgo biloba extract protects against mercury(II)-induced oxidative tissue damage in rats. Food Chem Toxicol 45(4):543-550 (Pubitemid 46209456)
27. Patnaik BB, Roy A, Agarwal S et al (2010) Induction of oxidative stress by non-lethal dose of mercury in rat liver: possible relationships between apoptosis and necrosis. J Environ Biol 31 (4):413-416
28. Blokhina O, Virolainen E, Fagerstedt KV (2002) Antioxidants, oxidative damage and oxygen deprivation stress: a review. Ann Bot 91:179-194
29. Hoffman DJ, Eagles-Smith CA, Ackerman JT et al (2011) Oxidative stress response of Forster's terns (Sterna forsteri) and Caspian terns (Hydroprogne caspia) to mercury and selenium bioaccumulation in liver, kidney, and brain. Environ Toxicol Chem 30(4):920-929
30. Rao MV, Chhunchha B (2010) Protective role of melatonin against the mercury induced oxidative stress in the rat thyroid. Food Chem Toxicol 48(1):7-10
31. Ji X, Wang W, Cheng J et al (2006) Free radicals and antioxidant status in rat liver after dietary exposure of environmental mercury. Environ Toxicol Pharmacol 22(3):309-314 (Pubitemid 44441966)
32. Cavusoglu K, Oruc E, Yapar K et al (2009) Protective effect of lycopene against mercury-induced cytotoxicity in albino mice: pathological evaluation. J Environ Biol 30(5 Suppl):807-814
33. Moselhy SS, Komousani TA (2011) Modulation of lead biohazards using a combination of epicatchin and lycopene in rats. Hum Exp Toxicol (in press)
34. Koul A, Arora N, Tanwar L (2010) Lycopene mediated modulation of 7,12 Dimethlybenz (a) anthracene induced hepatic clastogenicity in male Balb/c mice. Nutr Hosp 25(2):304-310
35. Huang CS, Hu ML (2011) Lycopene inhibits DNA damage and reduces hMTH1 mRNA expression in the liver of Mongolian gerbils treated with ferric nitrilotriacetate. Food Chem Toxicol 49 (6):1381-1386
36. Yousef MI, Saad AA, El-Shennawy LK (2009) Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats. Food Chem Toxicol 47(6):1176-1183
37. Bose KS, Agrawal BK (2007) Effect of lycopene from tomatoes (cooked) on plasma antioxidant enzymes, lipid peroxidation rate and lipid profile in grade-I hypertension. Ann Nutr Metab 51 (5):477-481 (Pubitemid 350212739)
38. Bahcecioglu IH, Kuzu N, Metin K et al (2010) Lycopene prevents development of steatohepatitis in experimental nonalcoholic steatohepatitis model induced by high-fat diet. Vet Med Int. pii:262179
39. Lu Y, ZhaoWZ, Chang Z, Chen WX, Li L (2004) Procyanidins from grape seeds protect against phorbol ester-induced oxidative cellular and genotoxic damage. Acta Pharmacol Sin 25(8):1083-1089 (Pubitemid 39071118)