메뉴 건너뛰기




Volumn 2, Issue 12, 2013, Pages 946-952

Concise review: Growth differentiation factor 15 in pathology: A clinical role?

Author keywords

Cancer; Clinical translation; Drug target; Malignancy

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BORTEZOMIB; C REACTIVE PROTEIN; CD34 ANTIGEN; DOCETAXEL; GROWTH DIFFERENTIATION FACTOR 15; HYPOXIA INDUCIBLE FACTOR 1; INTERLEUKIN 6; LENALIDOMIDE; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOXANTRONE; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; PROTEIN KINASE B; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; STAT3 PROTEIN; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA;

EID: 84888421123     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0055     Document Type: Article
Times cited : (165)

References (72)
  • 1
    • 12644256640 scopus 로고    scopus 로고
    • MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-_ superfamily
    • Bootcov MR, Bauskin AR, Valenzuela SM et al. MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-_ superfamily. Proc Natl Acad Sci USA 1997;94: 11514-11519.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11514-11519
    • Bootcov, M.R.1    Bauskin, A.R.2    Valenzuela, S.M.3
  • 2
    • 33845397898 scopus 로고    scopus 로고
    • NSAID activated gene (NAG-1), a modulator of tumorigenesis
    • Eling TE, Baek SJ, Shim M et al. NSAID activated gene (NAG-1), a modulator of tumorigenesis. J Biochem Mol Biol 2006;39: 649-655.
    • (2006) J Biochem Mol Biol , vol.39 , pp. 649-655
    • Eling, T.E.1    Baek, S.J.2    Shim, M.3
  • 3
    • 20144389237 scopus 로고    scopus 로고
    • The propeptide mediates formation of stromal stores of PROMIC-1: Role in determining prostate cancer outcome
    • Bauskin AR, Brown DA, Junankar S et al. The propeptide mediates formation of stromal stores of PROMIC-1: Role in determining prostate cancer outcome. Cancer Res 2005;65: 2330-2336.
    • (2005) Cancer Res , vol.65 , pp. 2330-2336
    • Bauskin, A.R.1    Brown, D.A.2    Junankar, S.3
  • 4
    • 0034702793 scopus 로고    scopus 로고
    • Expression of a TGF-beta superfamily protein, macrophage inhibitory cytokine-1, in the yeast Pichia pastoris
    • Fairlie WD, Zhang H, Brown PK et al. Expression of a TGF-beta superfamily protein, macrophage inhibitory cytokine-1, in the yeast Pichia pastoris. Gene 2000;254: 67-76.
    • (2000) Gene , vol.254 , pp. 67-76
    • Fairlie, W.D.1    Zhang, H.2    Brown, P.K.3
  • 5
    • 80052907593 scopus 로고    scopus 로고
    • The TGF-_ superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism
    • Breit SN, Johnen H, Cook AD et al. The TGF-_ superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism. Growth Factors 2011;29:187-195.
    • (2011) Growth Factors , vol.29 , pp. 187-195
    • Breit, S.N.1    Johnen, H.2    Cook, A.D.3
  • 6
    • 0030683569 scopus 로고    scopus 로고
    • PLAB, a novel placental bone morphogenetic protein
    • Hromas R, Hufford M, Sutton J et al. PLAB, a novel placental bone morphogenetic protein. Biochim Biophys Acta 1997;1354:40-44.
    • (1997) Biochim Biophys Acta , vol.1354 , pp. 40-44
    • Hromas, R.1    Hufford, M.2    Sutton, J.3
  • 7
    • 78649528682 scopus 로고    scopus 로고
    • Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma
    • Soucek K, Slabakova E, Ovesna P et al. Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma. Hum Reprod 2010;25:2962-2971.
    • (2010) Hum Reprod , vol.25 , pp. 2962-2971
    • Soucek, K.1    Slabakova, E.2    Ovesna, P.3
  • 8
    • 17744365158 scopus 로고    scopus 로고
    • The transforming growth factor-_ superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women
    • Moore AG, Brown DA, FairlieWDet al. The transforming growth factor-_ superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. J Clin Endocrinol Metab 2000;85:4781-4788.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4781-4788
    • Moore, A.G.1    Brown, D.A.2    Fairlie, W.D.3
  • 9
    • 0347318118 scopus 로고    scopus 로고
    • Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as a predictor of miscarriage
    • Tong S, Marjono B, Brown DA et al. Serum concentrations of macrophage inhibitory cytokine 1 (MIC 1) as a predictor of miscarriage. Lancet 2004;363:129-130.
    • (2004) Lancet , vol.363 , pp. 129-130
    • Tong, S.1    Marjono, B.2    Brown, D.A.3
  • 10
    • 78249249270 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 (MIC-1/ GDF15): A new marker of all-cause mortality
    • Wiklund FE, Bennet AM, Magnusson PK et al. Macrophage inhibitory cytokine-1 (MIC-1/ GDF15): A new marker of all-cause mortality. Aging Cell 2010;9:1057-1064.
    • (2010) Aging Cell , vol.9 , pp. 1057-1064
    • Wiklund, F.E.1    Bennet, A.M.2    Magnusson, P.K.3
  • 11
    • 79957496852 scopus 로고    scopus 로고
    • Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: The Rancho Bernardo Study
    • Daniels LB, Clopton P, Laughlin GA et al. Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: The Rancho Bernardo Study. Circulation 2011;123: 2101-2110.
    • (2011) Circulation , vol.123 , pp. 2101-2110
    • Daniels, L.B.1    Clopton, P.2    Laughlin, G.A.3
  • 12
  • 13
    • 77954604008 scopus 로고    scopus 로고
    • Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer
    • Mimeault M, Batra SK. Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer. J Cell Physiol 2010;224:626-635.
    • (2010) J Cell Physiol , vol.224 , pp. 626-635
    • Mimeault, M.1    Batra, S.K.2
  • 14
    • 0035881732 scopus 로고    scopus 로고
    • Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer
    • Welsh JB, Sapinoso LM, Su AI et al. Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res 2001;61:5974-5978.
    • (2001) Cancer Res , vol.61 , pp. 5974-5978
    • Welsh, J.B.1    Sapinoso, L.M.2    Su, A.I.3
  • 15
    • 0035477337 scopus 로고    scopus 로고
    • Secreted and cell surface genes expressed in benign and malignant colorectal tumors
    • Buckhaults P, Rago C, St Croix B et al. Secreted and cell surface genes expressed in benign and malignant colorectal tumors. Cancer Res 2001;61:6996-7001.
    • (2001) Cancer Res , vol.61 , pp. 6996-7001
    • Buckhaults, P.1    Rago, C.2    St Croix, B.3
  • 16
    • 10744223905 scopus 로고    scopus 로고
    • Serum diagnosis of pancreatic adenocarcinoma using surface-enhanced laser desorption and ionization mass spectrometry
    • Koopmann J, Zhang Z, White N et al. Serum diagnosis of pancreatic adenocarcinoma using surface-enhanced laser desorption and ionization mass spectrometry. Clin Cancer Res 2004;10:860-868.
    • (2004) Clin Cancer Res , vol.10 , pp. 860-868
    • Koopmann, J.1    Zhang, Z.2    White, N.3
  • 17
    • 67549138951 scopus 로고    scopus 로고
    • Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma
    • Zhang L, Yang X, Pan H-Y et al. Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma. Oral Oncol 2009;45:627-632.
    • (2009) Oral Oncol , vol.45 , pp. 627-632
    • Zhang, L.1    Yang, X.2    Pan, H.-Y.3
  • 18
    • 58449129853 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity
    • Boyle GM, Pedley J, Martyn AC et al. Macrophage inhibitory cytokine-1 is overexpressed in malignant melanoma and is associated with tumorigenicity. J Invest Dermatol 2009;129:383-391.
    • (2009) J Invest Dermatol , vol.129 , pp. 383-391
    • Boyle, G.M.1    Pedley, J.2    Martyn, A.C.3
  • 19
    • 77952477287 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 transactivates ErbB family receptors via the activation of Src in SK-BR-3 human breast cancer cells
    • Park YJ, Lee H, Lee JH. Macrophage inhibitory cytokine-1 transactivates ErbB family receptors via the activation of Src in SK-BR-3 human breast cancer cells. BMB Rep 2010;43: 91-96.
    • (2010) BMB Rep , vol.43 , pp. 91-96
    • Park, Y.J.1    Lee, H.2    Lee, J.H.3
  • 20
    • 77955100047 scopus 로고    scopus 로고
    • GDF-15 contributes to proliferation and immune escape of malignant gliomas
    • Roth P, Junker M, Tritschler I et al. GDF-15 contributes to proliferation and immune escape of malignant gliomas. Clin Cancer Res 2010;16:3851-3859.
    • (2010) Clin Cancer Res , vol.16 , pp. 3851-3859
    • Roth, P.1    Junker, M.2    Tritschler, I.3
  • 21
    • 0042134847 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system
    • Lee DH, Yang Y, Lee SJ et al. Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system. Cancer Res 2003;63:4648-4655.
    • (2003) Cancer Res , vol.63 , pp. 4648-4655
    • Lee, D.H.1    Yang, Y.2    Lee, S.J.3
  • 22
    • 34247556034 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells are abnormal in multiple myeloma
    • Corre J, Mahtouk K, Attal M et al. Bone marrow mesenchymal stem cells are abnormal in multiple myeloma. Leukemia 2007;21: 1079-1088.
    • (2007) Leukemia , vol.21 , pp. 1079-1088
    • Corre, J.1    Mahtouk, K.2    Attal, M.3
  • 23
    • 0034733530 scopus 로고    scopus 로고
    • Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells toDNAdamage and p53 overexpression
    • Li PX, Wong J, Ayed A et al. Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells toDNAdamage and p53 overexpression. J Biol Chem 2000;275: 20127-20135.
    • (2000) J Biol Chem , vol.275 , pp. 20127-20135
    • Li, P.X.1    Wong, J.2    Ayed, A.3
  • 24
    • 33750736082 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia
    • Baek SJ, Okazaki R, Lee SH et al. Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia. Gastroenterology 2006;131:1553-1560.
    • (2006) Gastroenterology , vol.131 , pp. 1553-1560
    • Baek, S.J.1    Okazaki, R.2    Lee, S.H.3
  • 25
    • 0036201713 scopus 로고    scopus 로고
    • Resveratrol enhances the expression of non-steroidal antiinflammatory drug-activated gene (NAG-1) by increasing the expression of p53
    • Baek SJ, Wilson LC, Eling TE. Resveratrol enhances the expression of non-steroidal antiinflammatory drug-activated gene (NAG-1) by increasing the expression of p53. Carcinogenesis 2002;23:425-434.
    • (2002) Carcinogenesis , vol.23 , pp. 425-434
    • Baek, S.J.1    Wilson, L.C.2    Eling, T.E.3
  • 26
    • 13444282673 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein
    • Baek SJ, Kim JS, Moore SM et al. Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR-1, which results in the up-regulation of NAG-1, an antitumorigenic protein. Mol Pharmacol 2005;67:356-364.
    • (2005) Mol Pharmacol , vol.67 , pp. 356-364
    • Baek, S.J.1    Kim, J.S.2    Moore, S.M.3
  • 27
    • 9644281593 scopus 로고    scopus 로고
    • Identification of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) as a novel downstream target of phosphatidylinositol 3-kinase/ AKT/GSK-3beta pathway
    • Yamaguchi K, Lee SH, Eling TE et al. Identification of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) as a novel downstream target of phosphatidylinositol 3-kinase/ AKT/GSK-3beta pathway. J Biol Chem 2004;279:49617-49623.
    • (2004) J Biol Chem , vol.279 , pp. 49617-49623
    • Yamaguchi, K.1    Lee, S.H.2    Eling, T.E.3
  • 28
    • 84858175766 scopus 로고    scopus 로고
    • Bioactivity and prognostic significance of growth differentiation factor GDF15 secreted by bone marrow mesenchymal stem cells in multiple myeloma
    • Corre J, Labat E, Espagnolle N et al. Bioactivity and prognostic significance of growth differentiation factor GDF15 secreted by bone marrow mesenchymal stem cells in multiple myeloma. Cancer Res 2012;72:1395-1406.
    • (2012) Cancer Res , vol.72 , pp. 1395-1406
    • Corre, J.1    Labat, E.2    Espagnolle, N.3
  • 29
    • 35348827924 scopus 로고    scopus 로고
    • Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: Identification of a cytoprotective mechanism involving growth differentiation factor 15
    • Huang C-Y, Beer TM, Higano CS et al. Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: Identification of a cytoprotective mechanism involving growth differentiation factor 15. Clin Cancer Res 2007;13:5825-5833.
    • (2007) Clin Cancer Res , vol.13 , pp. 5825-5833
    • Huang, C.-Y.1    Beer, T.M.2    Higano, C.S.3
  • 30
    • 0037646520 scopus 로고    scopus 로고
    • Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways
    • Subramaniam S, Strelau J, Unsicker K. Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways. J Biol Chem 2003;278: 8904-8912.
    • (2003) J Biol Chem , vol.278 , pp. 8904-8912
    • Subramaniam, S.1    Strelau, J.2    Unsicker, K.3
  • 31
    • 35948981520 scopus 로고    scopus 로고
    • Tumorinduced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1
    • Johnen H, Lin S, Kuffner T et al. Tumorinduced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med 2007;13:1333-1340.
    • (2007) Nat Med , vol.13 , pp. 1333-1340
    • Johnen, H.1    Lin, S.2    Kuffner, T.3
  • 32
    • 41849104687 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells
    • Kim KK, Lee JJ, Yang Y et al. Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells. Carcinogenesis 2008;29:704-712.
    • (2008) Carcinogenesis , vol.29 , pp. 704-712
    • Kim, K.K.1    Lee, J.J.2    Yang, Y.3
  • 33
    • 33646076196 scopus 로고    scopus 로고
    • GDF15/ MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation
    • Xu J, Kimball TR, Lorenz JN et al. GDF15/ MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation. Circ Res 2006;98:342-350.
    • (2006) Circ Res , vol.98 , pp. 342-350
    • Xu, J.1    Kimball, T.R.2    Lorenz, J.N.3
  • 34
    • 79951708423 scopus 로고    scopus 로고
    • Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis
    • de Jager SCA, Bermudez B, Bot I et al. Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis. J Exp Med 2011;208:217-225.
    • (2011) J Exp Med , vol.208 , pp. 217-225
    • de Jager, S.C.A.1    Bermudez, B.2    Bot, I.3
  • 35
    • 77953217053 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 regulates melanoma vascular development
    • Huh SJ, Chung CY, Sharma A et al. Macrophage inhibitory cytokine-1 regulates melanoma vascular development. Am J Pathol 2010;176:2948-2957.
    • (2010) Am J Pathol , vol.176 , pp. 2948-2957
    • Huh, S.J.1    Chung, C.Y.2    Sharma, A.3
  • 36
    • 0037142612 scopus 로고    scopus 로고
    • Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1
    • Albertoni M, Shaw PH, Nozaki M et al. Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 2002;21: 4212-4219.
    • (2002) Oncogene , vol.21 , pp. 4212-4219
    • Albertoni, M.1    Shaw, P.H.2    Nozaki, M.3
  • 37
    • 0043016358 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells
    • Liu T, Bauskin AR, Zaunders J et al. Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells. Cancer Res 2003;63:5034-5040.
    • (2003) Cancer Res , vol.63 , pp. 5034-5040
    • Liu, T.1    Bauskin, A.R.2    Zaunders, J.3
  • 38
    • 77949267633 scopus 로고    scopus 로고
    • Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway
    • Senapati S, Rachagani S, Chaudhary K et al. Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK-RhoA signaling pathway. Oncogene 2010;29:1293-1302.
    • (2010) Oncogene , vol.29 , pp. 1293-1302
    • Senapati, S.1    Rachagani, S.2    Chaudhary, K.3
  • 39
    • 65549164721 scopus 로고    scopus 로고
    • Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss
    • Wakchoure S, Swain TM, Hentunen TA et al. Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss. Prostate 2009;69:652-661.
    • (2009) Prostate , vol.69 , pp. 652-661
    • Wakchoure, S.1    Swain, T.M.2    Hentunen, T.A.3
  • 40
    • 84863378777 scopus 로고    scopus 로고
    • Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia
    • Hinoi E, Ochi H, Takarada T et al. Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia. J Bone Miner Res 2012;27:938-949.
    • (2012) J Bone Miner Res , vol.27 , pp. 938-949
    • Hinoi, E.1    Ochi, H.2    Takarada, T.3
  • 41
    • 80054022144 scopus 로고    scopus 로고
    • The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma
    • Martin SK, Diamond P, Gronthos S et al. The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma. Leukemia 2011;25: 1533-1542.
    • (2011) Leukemia , vol.25 , pp. 1533-1542
    • Martin, S.K.1    Diamond, P.2    Gronthos, S.3
  • 42
    • 12444303172 scopus 로고    scopus 로고
    • MIC-1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma
    • Brown DA, Ward RL, Buckhaults P et al. MIC-1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma. Clin Cancer Res 2003;9:2642-2650.
    • (2003) Clin Cancer Res , vol.9 , pp. 2642-2650
    • Brown, D.A.1    Ward, R.L.2    Buckhaults, P.3
  • 43
    • 63849269523 scopus 로고    scopus 로고
    • Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes
    • Ding Q, Mracek T, Gonzalez-Muniesa P et al. Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. Endocrinology 2009;150:1688-1696.
    • (2009) Endocrinology , vol.150 , pp. 1688-1696
    • Ding, Q.1    Mracek, T.2    Gonzalez-Muniesa, P.3
  • 44
    • 70350733627 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine 1: A new prognostic marker in prostate cancer
    • Brown DA, Lindmark F, Stattin P et al. Macrophage inhibitory cytokine 1: A new prognostic marker in prostate cancer. Clin Cancer Res 2009;15:6658-6664.
    • (2009) Clin Cancer Res , vol.15 , pp. 6658-6664
    • Brown, D.A.1    Lindmark, F.2    Stattin, P.3
  • 45
    • 31544450588 scopus 로고    scopus 로고
    • Serum markers in patients with resectable pancreatic adenocarcinoma: Macrophage inhibitory cytokine 1 versus CA19-9
    • Koopmann J, Rosenzweig CN, Zhang Z et al. Serum markers in patients with resectable pancreatic adenocarcinoma: Macrophage inhibitory cytokine 1 versus CA19-9. Clin Cancer Res 2006;12:442-446.
    • (2006) Clin Cancer Res , vol.12 , pp. 442-446
    • Koopmann, J.1    Rosenzweig, C.N.2    Zhang, Z.3
  • 46
    • 77955555369 scopus 로고    scopus 로고
    • Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer
    • Staff AC, Bock AJ, Becker C et al. Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer. Gynecol Oncol 2010; 118:237-243.
    • (2010) Gynecol Oncol , vol.118 , pp. 237-243
    • Staff, A.C.1    Bock, A.J.2    Becker, C.3
  • 47
    • 79960390271 scopus 로고    scopus 로고
    • Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer
    • Staff AC, Trovik J, Zahl EAG et al. Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer. Clin Cancer Res 2011;17:4825-4833.
    • (2011) Clin Cancer Res , vol.17 , pp. 4825-4833
    • Staff, A.C.1    Trovik, J.2    Zahl, E.A.G.3
  • 48
    • 79954610158 scopus 로고    scopus 로고
    • Plasma markers for identifying patients with metastatic melanoma
    • Kluger HM, Hoyt K, Bacchiocchi A et al. Plasma markers for identifying patients with metastatic melanoma. Clin Cancer Res 2011; 17:2417-2425.
    • (2011) Clin Cancer Res , vol.17 , pp. 2417-2425
    • Kluger, H.M.1    Hoyt, K.2    Bacchiocchi, A.3
  • 49
    • 34948904750 scopus 로고    scopus 로고
    • High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin
    • Tanno T, Bhanu NV, Oneal PA et al. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med 2007;13:1096-1101.
    • (2007) Nat Med , vol.13 , pp. 1096-1101
    • Tanno, T.1    Bhanu, N.V.2    Oneal, P.A.3
  • 50
    • 58149399349 scopus 로고    scopus 로고
    • Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I
    • Tamary H, Shalev H, Perez-Avraham G et al. Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I. Blood 2008;112: 5241-5244.
    • (2008) Blood , vol.112 , pp. 5241-5244
    • Tamary, H.1    Shalev, H.2    Perez-Avraham, G.3
  • 51
    • 58149092194 scopus 로고    scopus 로고
    • Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts
    • Ramirez JM, Schaad O, Durual S et al. Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts. Br J Haematol 2009;144: 251-262.
    • (2009) Br J Haematol , vol.144 , pp. 251-262
    • Ramirez, J.M.1    Schaad, O.2    Durual, S.3
  • 52
    • 58849084155 scopus 로고    scopus 로고
    • Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency
    • Finkenstedt A, Bianchi P, Theurl I et al. Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency. Br J Haematol 2009;144:789-793.
    • (2009) Br J Haematol , vol.144 , pp. 789-793
    • Finkenstedt, A.1    Bianchi, P.2    Theurl, I.3
  • 53
    • 84866856496 scopus 로고    scopus 로고
    • Multiple myeloma-related deregulation of bone marrow-derived CD34_ hematopoietic stem and progenitor cells
    • Bruns I, Cadeddu R-P, Brueckmann I et al. Multiple myeloma-related deregulation of bone marrow-derived CD34_ hematopoietic stem and progenitor cells. Blood 2012;120: 2620-2630.
    • (2012) Blood , vol.120 , pp. 2620-2630
    • Bruns, I.1    Cadeddu, R.-P.2    Brueckmann, I.3
  • 54
    • 0037157611 scopus 로고    scopus 로고
    • Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: A nested case-control study
    • Brown DA, Breit SN, Buring J et al. Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: A nested case-control study. Lancet 2002;359:2159-2163.
    • (2002) Lancet , vol.359 , pp. 2159-2163
    • Brown, D.A.1    Breit, S.N.2    Buring, J.3
  • 55
    • 34548042897 scopus 로고    scopus 로고
    • Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure
    • Kempf T, von Haehling S, Peter T et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure. J Am Coll Cardiol 2007;50:1054-1060.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1054-1060
    • Kempf, T.1    von Haehling, S.2    Peter, T.3
  • 56
    • 36849078690 scopus 로고    scopus 로고
    • Growth-differentiation factor-15 improves risk stratification in ST-segment elevation myocardial infarction
    • Kempf T, Bjorklund E, Olofsson S et al. Growth-differentiation factor-15 improves risk stratification in ST-segment elevation myocardial infarction. Eur Heart J 2007;28:2858-2865.
    • (2007) Eur Heart J , vol.28 , pp. 2858-2865
    • Kempf, T.1    Bjorklund, E.2    Olofsson, S.3
  • 57
    • 33847284450 scopus 로고    scopus 로고
    • Prognostic value of growth-differentiation factor-15 in patients with non-ST-elevation acute coronary syndrome
    • Wollert KC, Kempf T, Peter T et al. Prognostic value of growth-differentiation factor-15 in patients with non-ST-elevation acute coronary syndrome. Circulation 2007;115: 962-971.
    • (2007) Circulation , vol.115 , pp. 962-971
    • Wollert, K.C.1    Kempf, T.2    Peter, T.3
  • 58
    • 42949127572 scopus 로고    scopus 로고
    • Growth differentiation factor-15 for prognostic assessment of patients with acute pulmonary embolism
    • Lankeit M, Kempf T, Dellas C et al. Growth differentiation factor-15 for prognostic assessment of patients with acute pulmonary embolism. Am J Respir Crit Care Med 2008;177:1018-1025.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1018-1025
    • Lankeit, M.1    Kempf, T.2    Dellas, C.3
  • 59
    • 51349094371 scopus 로고    scopus 로고
    • Growth differentiation factor-15 in idiopathic pulmonary arterial hypertension
    • Nickel N, Kempf T, Tapken H et al. Growth differentiation factor-15 in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med 2008;178:534-541.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 534-541
    • Nickel, N.1    Kempf, T.2    Tapken, H.3
  • 60
    • 70350070778 scopus 로고    scopus 로고
    • Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy
    • Foley PW, Stegemann B, Ng K et al. Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy. Eur Heart J 2009;30:2749-2757.
    • (2009) Eur Heart J , vol.30 , pp. 2749-2757
    • Foley, P.W.1    Stegemann, B.2    Ng, K.3
  • 61
    • 79960174921 scopus 로고    scopus 로고
    • Growth differentiation factor 15: An additional diagnostic tool for the risk stratification of developing heart failure in patients with operated congenital heart defects?
    • Norozi K, Buchhorn R, Yasin A et al. Growth differentiation factor 15: An additional diagnostic tool for the risk stratification of developing heart failure in patients with operated congenital heart defects? Am Heart J 2011;162:131-135.
    • (2011) Am Heart J , vol.162 , pp. 131-135
    • Norozi, K.1    Buchhorn, R.2    Yasin, A.3
  • 62
    • 84872174624 scopus 로고    scopus 로고
    • Growth differentiation factor 15 in heart failure: An update
    • Wollert KC, Kempf T. Growth differentiation factor 15 in heart failure: An update. Curr Heart Fail Rep 2012;9:337-345.
    • (2012) Curr Heart Fail Rep , vol.9 , pp. 337-345
    • Wollert, K.C.1    Kempf, T.2
  • 63
    • 84868520076 scopus 로고    scopus 로고
    • Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE(_/_) mice from the development of atherosclerosis
    • Johnen H, Kuffner T, Brown DA et al. Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE(_/_) mice from the development of atherosclerosis. Cardiovasc Pathol 2012;21:499-505.
    • (2012) Cardiovasc Pathol , vol.21 , pp. 499-505
    • Johnen, H.1    Kuffner, T.2    Brown, D.A.3
  • 64
    • 84881247815 scopus 로고    scopus 로고
    • Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury
    • Bonaterra GA, Zugel S, Thogersen J et al. Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury. J Am Heart Assoc 2012;1:e002550.
    • (2012) J Am Heart Assoc , vol.1
    • Bonaterra, G.A.1    Zugel, S.2    Thogersen, J.3
  • 65
    • 33646076691 scopus 로고    scopus 로고
    • The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury
    • Kempf T, Eden M, Strelau J et al. The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury. Circ Res 2006;98:351-360.
    • (2006) Circ Res , vol.98 , pp. 351-360
    • Kempf, T.1    Eden, M.2    Strelau, J.3
  • 66
    • 80051962950 scopus 로고    scopus 로고
    • Growth differentiation factor 15 in cardiovascular diseases: From bench to bedside
    • Xu X, Li Z, Gao W. Growth differentiation factor 15 in cardiovascular diseases: From bench to bedside. Biomarkers 2011;16:466-475.
    • (2011) Biomarkers , vol.16 , pp. 466-475
    • Xu, X.1    Li, Z.2    Gao, W.3
  • 67
    • 33947153891 scopus 로고    scopus 로고
    • Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis. A potential marker of erosive joint destruction
    • Brown DA, Moore J, Johnen H et al. Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis. A potential marker of erosive joint destruction. Arthritis Rheum 2007;56: 753-764.
    • (2007) Arthritis Rheum , vol.56 , pp. 753-764
    • Brown, D.A.1    Moore, J.2    Johnen, H.3
  • 68
    • 84863034556 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease
    • Breit SN, Carrero JJ, Tsai VW et al. Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease. Nephrol Dial Transplant 2012;27:70-75.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 70-75
    • Breit, S.N.1    Carrero, J.J.2    Tsai, V.W.3
  • 69
    • 84868100661 scopus 로고    scopus 로고
    • Growth-differentiation factor 15 predicts worsening of albuminuria in patients with type 2 diabetes
    • Hellemons ME, Mazagova M, Gansevoort RT et al. Growth-differentiation factor 15 predicts worsening of albuminuria in patients with type 2 diabetes. Diabetes Care 2012;35:2340-2346.
    • (2012) Diabetes Care , vol.35 , pp. 2340-2346
    • Hellemons, M.E.1    Mazagova, M.2    Gansevoort, R.T.3
  • 70
    • 84871206841 scopus 로고    scopus 로고
    • Local substitution of GDF-15 improves axonal and sensory recovery after peripheral nerve injury
    • Mensching L, Börger AK, Wang X et al. Local substitution of GDF-15 improves axonal and sensory recovery after peripheral nerve injury. Cell Tissue Res 2012;350:225-238.
    • (2012) Cell Tissue Res , vol.350 , pp. 225-238
    • Mensching, L.1    Börger, A.K.2    Wang, X.3
  • 71
    • 0034056778 scopus 로고    scopus 로고
    • Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury
    • Hsiao EC, Koniaris LG, Zimmers-Koniaris T et al. Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury. Mol Cell Biol 2000;20:3742-3751.
    • (2000) Mol Cell Biol , vol.20 , pp. 3742-3751
    • Hsiao, E.C.1    Koniaris, L.G.2    Zimmers-Koniaris, T.3
  • 72
    • 70350528733 scopus 로고    scopus 로고
    • Progressive postnatal motoneuron loss in mice lacking GDF-15
    • Strelau J, Strzelczyk A, RusuPet al. Progressive postnatal motoneuron loss in mice lacking GDF-15. J Neurosci 2009;29:13640-13648.
    • (2009) J Neurosci , vol.29 , pp. 13640-13648
    • Strelau, J.1    Strzelczyk, A.2    Rusu, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.