Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease

Nephrology Dialysis Transplantation

Volumn 27, Issue 1, 2012, Pages 70-75

  Breit, Samuel N ^a   Carrero, Juan J ^b   Tsai, Vicky Wang Wei ^a   Yagoutifam, Nasreen ^a   Luo, Wei ^a   Kuffner, Tamara ^a   Bauskin, Asne R ^a   Wu, Liyun ^a   Jiang, Lele ^a   Barany, Peter ^b   Heimburger, Olof ^b   Murikami, Mary Ann ^c   Apple, Fred S ^c   Marquis, Christopher P ^a   MacIa, Laurence ^d   Lin, Shu ^d   Sainsbury, Amanda ^d   Herzog, Herbert ^d   Law, Matthew ^e   Stenvinkel, Peter ^b   Brown, David A ^a   more..

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

all cause mortality; end stage renal failure; hemodialysis; MIC 1 GDF15

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; GROWTH DIFFERENTIATION FACTOR 15;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; CHRONIC INFLAMMATION; DISEASE ASSOCIATION; FEMALE; HUMAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MORTALITY; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SWEDEN; UNITED STATES;

C-REACTIVE PROTEIN; COHORT STUDIES; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; IMMUNOENZYME TECHNIQUES; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; RENAL DIALYSIS; RISK FACTORS; SURVIVAL RATE; SWEDEN; UNITED STATES;

EID: 84863034556     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr575     Document Type: Article

References (33)

1. Foley RN, Collins AJ. End-stage renal disease in the United States: an update from the United States Renal Data System. J Am Soc Nephrol 2007; 18: 2644-2648 (Pubitemid 47531190)
2. Apple FS, Murakami MM, Pearce LA et al. Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death. Clin Chem 2004; 50: 2279-2285 (Pubitemid 39552162)
3. Horwich TB, Fonarow GC. Reverse epidemiology beyond dialysis patients: chronic heart failure, geriatrics, rheumatoid arthritis, COPD, and AIDS. Semin Dial 2007; 20: 549-553
4. Fouque D, Kalantar-Zadeh K, Kopple J et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int 2008; 73: 391-398 (Pubitemid 351186278)
5. de Mutsert R, Grootendorst DC, Indemans F et al. Association between serum albumin and mortality in dialysis patients is partly explained by inflammation, and not by malnutrition. J Ren Nutr 2009; 19: 127-135
6. Kalantar-Zadeh K, Balakrishnan VS. The kidney disease wasting: inflammation, oxidative stress, and diet-gene interaction. Hemodial Int 2006; 10: 315-325 (Pubitemid 44489914)
7. Brown DA, Breit SN, Buring J et al. Concentration in plasma of macro-phage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study. Lancet 2002; 359: 2159-2163 (Pubitemid 34694024)
8. Bauskin AR, Brown DA, Kuffner T et al. Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer. Cancer Res 2006; 66: 4983-4986 (Pubitemid 43852864)
9. Bootcov MR, Bauskin AR, Valenzuela SM et al. MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci USA 1997; 94: 11514-11519 (Pubitemid 27451030)
10. Brown DA, Moore J, Johnen H et al. Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis: a potential marker of erosive joint destruction. Arthritis Rheum 2007; 56: 753-764 (Pubitemid 46399422)
11. Brown DA, Ward RL, Buckhaults P et al. MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma. Clin Cancer Res 2003; 9: 2642-2650 (Pubitemid 36842108)
12. Selander KS, Brown DA, Sequeiros GB et al. Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases. Cancer Epidemiol Biomarkers Prev 2007; 16: 532-537 (Pubitemid 46548657)
13. Johnen H, Lin S, Kuffner T et al. Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat Med 2007; 13: 1333-1340 (Pubitemid 350073601)
14. Wiklund FE, Bennet AM, Magnusson PK et al. Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality. Aging Cell 2010; 9: 1057-1064
15. Brown DA, Bauskin AR, Fairlie WD et al. Antibody-based approach to high-volume genotyping for MIC-1 polymorphism. Biotechniques 2002; 33: 118-120., 122, 124 passim
16. Stenvinkel P, Heimburger O, Paultre F et al. Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int 1999; 55: 1899-1911 (Pubitemid 29197978)
17. Qureshi AR, Alvestrand A, Danielsson A et al. Factors predicting malnutrition in hemodialysis patients: a cross-sectional study. Kidney Int 1998; 53: 773-782 (Pubitemid 28124295)
18. Kyle UG, Schutz Y, Dupertuis YM et al. Body composition interpretation. Contributions of the fat-free mass index and the body fat mass index. Nutrition 2003; 19: 597-604 (Pubitemid 36794286)
19. Apple FS, Murakami MM, Pearce LA et al. Predictive value of cardiac troponin I and T for subsequent death in end-stage renal disease. Circulation 2002; 106: 2941-2945 (Pubitemid 35424746)
20. Moore AG, Brown DA, Fairlie WD et al. The transforming growth factor-ß superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. J Clin Endocrinol Metab 2000; 85: 4781-4788 (Pubitemid 32157666)
21. Brown DA, Stephan C, Ward RL et al. Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis. Clin Cancer Res 2006; 12: 89-96 (Pubitemid 43166181)
22. Stenvinkel P, Carrero JJ, Axelsson J et al. Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle? Clin J Am Soc Nephrol 2008; 3: 505-521
23. Kempf T, von Haehling S, Peter T et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure. J Am Coll Cardiol 2007; 50: 1054-1060 (Pubitemid 47348231)
24. Scholze A, Rattensperger D, Zidek W et al. Low serum leptin predicts mortality in patients with chronic kidney disease stage 5. Obesity (Silver Spring) 2007; 15: 1617-1622 (Pubitemid 47110926)
25. Ohashi N, Kato A, Misaki T et al. Association of serum adiponectin levels with all-cause mortality in hemodialysis patients. Intern Med 2008; 47: 485-491 (Pubitemid 351663663)
26. Daniels LB, Clopton P, Laughlin GA et al. Growth-differentiation factor-15 is a robust, independent predictor of 11-year mortality risk in community-dwelling older adults: the Rancho Bernardo Study. Circulation 2011; 123: 2101-2110
27. Himmelfarb J, Stenvinkel P, Ikizler TA et al. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002; 62: 1524-1538 (Pubitemid 35286260)
28. Halliwell B. Oxidative stress and cancer: have we moved forward? Biochem J 2007; 401: 1-11 (Pubitemid 46115897)
29. Locatelli F, Canaud B, Eckardt KU et al. Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrol Dial Transplant 2003; 18: 1272-1280 (Pubitemid 36826946)
30. Yang H, Filipovic Z, Brown D et al. Macrophage inhibitory cytokine-1: a novel biomarker for p.53 pathway activation. Mol Cancer Ther 2003; 2: 1023-1029
31. Lotze MT, Zeh HJ, Rubartelli A et al. The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol Rev 2007; 220: 60-81 (Pubitemid 350045579)
32. Nordfors L, Lindholm B, Stenvinkel P. End-stage renal disease-not an equal opportunity disease: the role of genetic polymorphisms. J Intern Med 2005; 258: 1-12 (Pubitemid 40904927)
33. Sung RS, Galloway J, Tuttle-Newhall JE et al. Organ donation and utilization in the United States, 1997-2006. Am J Transplant 2008; 8: 922-934 (Pubitemid 351389062)