Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia

Journal of Bone and Mineral Research

Volumn 27, Issue 4, 2012, Pages 938-949

  Hinoi, Eiichi ^a   Ochi, Hiroki ^b   Takarada, Takeshi ^a   Nakatani, Eri ^a   Iezaki, Takashi ^a   Nakajima, Hiroko ^a   Fujita, Hiroyuki ^a   Takahata, Yoshifumi ^a   Hidano, Shinya ^b   Kobayashi, Takashi ^b   Takeda, Shu ^b   Yoneda, Yukio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

GDF15; HYPOXIA; osteoblast; osteoclast; osteocyte

Indexed keywords

DENTIN MATRIX PROTEIN 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GROWTH DIFFERENTIATION FACTOR 15; GROWTH DIFFERENTIATION FACTOR 15 ANTIBODY; HEME OXYGENASE 1; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE MIGRATION INHIBITION FACTOR; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN ANTIBODY; SECRETED FRIZZLED RELATED PROTEIN 1; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; BONE DENSITY; BONE REMODELING; CANCELLOUS BONE; CELL DEATH; CELL HYPOXIA; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FEMALE; FEMORAL ARTERY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; OSTEOCYTE; OSTEOLYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; TIBIA; UPREGULATION;

ANIMALS; ANTIBODIES; BONE RESORPTION; CELL DIFFERENTIATION; CELL HYPOXIA; COBALT; FEMORAL ARTERY; GROWTH DIFFERENTIATION FACTOR 15; LIGATION; MICE; MICE, INBRED C57BL; NF-KAPPA B; OSTEOCLASTS; OSTEOCYTES; RANK LIGAND; SIGNAL TRANSDUCTION; SOLUBILITY; UP-REGULATION;

EID: 84863378777     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1538     Document Type: Article

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