Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE-/- mice from the development of atherosclerosis

Cardiovascular Pathology

Volumn 21, Issue 6, 2012, Pages 499-505

  Johnen, Heiko ^a,c   Kuffner, Tamara ^a   Brown, David A ^a   Wu, Ben J ^b,d   Stocker, Roland ^b,e   Breit, Samuel N ^a  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^d HEART RESEARCH INSTITUTE   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

ApoE mouse model of atherosclerosis; Atherosclerosis pathogenesis; GDF15; MIC 1

Indexed keywords

APOLIPOPROTEIN E; CYTOKINE; GAMMA INTERFERON; GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 12; INTERLEUKIN 6; LIPID; MONOCYTE CHEMOTACTIC PROTEIN 1;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA SINUS; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BODY WEIGHT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE OVEREXPRESSION; LIPID BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIVER FUNCTION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; THORACIC AORTA;

ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; CHOLESTEROL, DIETARY; CYTOKINES; DIET, ATHEROGENIC; DISEASE MODELS, ANIMAL; GROWTH DIFFERENTIATION FACTOR 15; LIPIDS; MACROPHAGES; MICE; MICE, KNOCKOUT;

EID: 84868520076     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2012.02.003     Document Type: Article

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