Placental transforming growth factor-β is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression

Journal of Biological Chemistry

Volumn 275, Issue 26, 2000, Pages 20127-20135

  Li, Pei Xiang ^a,b   Wong, Jeffrey ^a,b   Ayed, Ayeda ^a,b   Ngo, Duc ^a,b   Brade, Anthony M ^a,b   Arrowsmith, Cheryl ^a   Austin, Richard C ^c   Klamut, Henry J ^a,b,d  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF ONTARIO INSTITUTE OF TECHNOLOGY   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL CULTURE; CELL CYCLE; CELL DEATH; CYTOSTASIS; DNA DAMAGE; GENE OVEREXPRESSION; GROWTH DISORDER; HUMAN; HUMAN CELL; PLACENTA; PRIORITY JOURNAL; RADIATION INJURY; SIGNAL TRANSDUCTION;

ADENOVIRIDAE; APOPTOSIS; BLOTTING, NORTHERN; BREAST NEOPLASMS; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; DNA DAMAGE; DNA, COMPLEMENTARY; GENES, P53; GENETIC VECTORS; GROWTH SUBSTANCES; HUMANS; PREGNANCY PROTEINS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TIME FACTORS; TISSUE DISTRIBUTION; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0034733530     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M909580199     Document Type: Article

References (86)

1. Weichselbaum, R. R., Beckett, M. A., Hallahan, D. E., Kufe, D. W., and Vokes, E. E. (1992) Semin. Oncol. 19, 14-20
2. Levine, A. J. (1997) Cell 88, 323-331
3. Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. (1993) Cell 74, 957-967
4. Lane, D. P. (1992) Nature 358, 15-16
5. el-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817-825
6. Miyashita, T., and Reed, J. C. (1995) Cell 80, 293-299
7. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K., and Elledge, S. J. (1993) Cell 75, 805-816
8. Hartwell, L. H., and Kastan, M. B. (1994) Science 266, 1821-1828
9. Zhan, Q., Chen, I. T., Antinore, M. J., and Fornace, A. J., Jr. (1998) Mol. Cell. Biol. 18, 2768-2778
10. Hermeking, H., Lengauer, C., Polyak, K., He, T. C., Zhang, L., Thiagalingam, S., Kinzler, K. W., and Vogelstein, B. (1997) Mol. Cell 1, 3-11
11. Utrera, R., Collavin, L., Lazarevic, D., Delia, D., and Schneider, C. (1998) EMBO J. 17, 5015-5025
12. Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., and Oren, M. (1991) Nature 352, 345-347
13. Miyashita, T., Krajewski, S., Krajewska, M., Wang, H. G., Lin, H. K., Liebermann, D. A., Hoffman, B., and Reed, J. C. (1994) Oncogene 9, 1799-1805
14. Owen-Schaub, L. B., Zhang, W., Cusack, J. C., Angelo, L. S., Santee, S. M., Fujiwara, T., Roth, J. A., Deisseroth, A. B., Zhang, W. W., Kruzel, E., and Radinsky, R. (1995) Mol. Cell. Biol. 15, 3032-3040
15. Wu, G. S., Burns, T. F., McDonald, E. R., III, Jiang, W., Meng, R., Krantz, I. D., Kao, G., Gan, D. D., Zhou, J. Y., Muschel, R., Hamilton, S. R., Spinner, N. B., Markowitz, S., Wu, G., and el-Deiry, W. S. (1997) Nat. Genet. 17, 141-143
16. Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., and Vogelstein, B. (1997) Nature 389, 300-305
17. Buckbinder, L., Talbott, R., Velasco-Miguel, S.. Takenaka, I., Faha, B., Seizinger, B. R., and Hey, N. (1995) Nature 377, 646-649
18. Israeli, D., Tessler, E., Haupt, Y., Elkeles, A., Wilder, S., Amson, R., Telerman, A., and Oren, M. (1997) EMBO J. 16, 4384-4392
19. Rosse, T., Olivier, R., Monney, L., Rager, M., Conus, S., Fellay, I., Jansen, B., and Borner, C. (1998) Nature 391, 496-499
20. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P., and Wang, X. (1997) Science 275, 1129-1132
21. Knudson, C. M., Tung, K. S., Tourtellotte, W. G., Brown, G. A., and Korsmeyer, S. J. (1995) Science 270, 96-99
22. Fuchs, E. J., McKenna, K. A., and Bedi, A. (1997) Cancer Res. 57, 2550-2554
23. Yount, G. L., Levine, K. S., Kuriyama, H., Haas-Kogan, D. A., and Israel, M. A. (1999) Cancer Res. 59, 1362-1365
24. Yeh, W. C., Pompa, J. L., McCurrach, M. E., Shu, H. B., Elia, A. J., Shahinian, A., Ng, M., Wakeham, A., Khoo, W., Mitchell, K., El-Deiry, W. S., Lowe, S. W., Goeddel, D. V., and Mak, T. W. (1998) Science 279, 1954-1958
25. Vogelstein, B., and Kinzler, K. W. (1992) Cell 70, 523-526
26. Lowe, S. W., Bodis, S., McClatchey, A., Remington, L., Ruley, H. E., Fisher, D. E., Housman, D. E., and Jacks, T. (1994) Science 266, 807-810
27. Brown, J. M., and Wouters, B. G. (1999) Cancer Res. 59, 1391-1399
28. Li, P. X., Ngo, D., Brade, A. M., and Klamut, H. J. (1999) Cancer Gene Ther 6, 179-190
29. Peled, A., Zipori, D., and Rotter, V. (1996) Cancer Res. 56, 2148-2156
30. Lawton, L. N., Bonaldo, M. F., Jelenc, P. C., Qiu, L., Baumes, S. A., Marcelino, R. A., de Jesus, G. M., Wellington, S., Knowles, J. A., Warburton, D., Brown, S., and Soares, M. B. (1997) Gene (Amst.) 203, 17-26
31. Hromas, R., Hufford, M., Sutton, J., Xu, D., Li, Y., and Lu, L. (1997) Biochim. Biophys. Acta 1354, 40-44
32. Massague, J. (1990) Annu. Rev. Cell Biol. 6, 597-641
33. Hoodless, P. A., and Wrana, J. L. (1998) Curr. Topics Microbiol. Immunol. 228, 235-272
34. Li, P., Bui, T., Gray, D., and Klamut, H. J. (1998) Breast Cancer Res. Treat. 48, 273-286
35. Brancolini, C., Lazarevic, D., Rodriguez, J., and Schneider, C. (1997) J. Cell Biol. 139, 759-771
36. Outinen, P. A., Sood, S. K., Liaw, P. C., Sarge, K. D., Maeda, N., Hirsh, J., Ribau, J., Podor, T. J., Weitz, J. I., and Austin, R. C. (1998) Biochem. J. 332, 213-221
37. Chen, C. A., and Okayama, H. (1988) BioTechniques 6, 632-638
38. Wrana, J. L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. F., and Massague, J. (1992) Cell 71, 1003-1014
39. el-Deiry, W. S., Kern, S. E., Pietenpol, J. A., Kinzler, K. W., and Vogelstein, B. (1992) Nat. Genet. 1, 45-49
40. Wolkowicz, R., Peled, A., Elkind, N. B., and Rotter, V. (1998) Cancer Detect. Prev. 22, 1-13
41. Lee, W., Harvey, T. S., Yin, Y., Yau, P., Litchfield, D., and Arrowsmith, C. H. (1994) Nat. Struct. Biol. 1, 877-890
42. Bett, A. J., Haddara, W., Prevec, L., and Graham, F. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8802-8806
43. Liebentiann, D. A., Hoffman, B., and Steinman, R. A. (1995) Oncogene 11, 199-210
44. Nishizaki, M., Fujiwara, T., Tanida, T., Hizuta, A., Nishimori, H., Tokino, T., Nakamura, Y., Bouvet, M., Roth, J. A., and Tanaka, N. (1999) Clin. Cancer Res. 5, 1015-1023
45. Liang, P., Bauer, D., Averboukh, L., Warthoe, P., Rohrwild, M., Muller, H., Strauss, M., and Pardee, A. B. (1995) Methods Enzymol. 254, 304-321
46. Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary, K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F. S., Weston, A., Modali, R., Harris, C. C., and Vogelstein, B. (1989) Nature 342, 705-708
47. Milner, J. (1995) Nat. Med. 1, 879-880
48. Yokoyama-Kobayashi, M., Saeki, M., Sekine, S., and Kato, S. (1997) J. Biochem. (Tokyo) 122, 622-626
49. Bootcov, M. R., Bauskin, A. R., Valenzuela, S. M., Moore, A. G., Bansal, M., He, X. Y., Zhang, H. P., Donnellan, M., Mahler, S., Pryor, K., Walsh, B. J., Nicholson, R. C., Fairlie, W. D., Por, S. B., Robbins, J. M., and Breit, S. N. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 11514-11519
50. Paralkar, V. M., Vail, A. L., Grasser, W. A., Brown, T. A., Xu, H., Vukicevic, S., Ke, H. Z., Qi, H., Owen, T. A., and Thompson, D. D. (1998) J. Biol. Chem. 273, 13760-13767
51. Weinstein, D. C., Ruiz, Chen, W. S., Hoodless, P., Prezioso, V. R., Jessell, T. M., and Darnell, J. E., Jr. (1994) Cell 78, 575-588
52. Sirito, M., Lin, Q., Deng, J. M., Behringer, R. R., and Sawadogo, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3758-3763
53. Frumkin, A., Pillemer, G., Haffner, R., Tarcic, N., Gruenbaum, Y., and Fainsod, A. (1994) Development 120, 253-263
54. Meyers, S., Downing, J. R., and Hiebert, S. W. (1993) Mol. Cell. Biol. 13, 6336-6345
55. Towatari, M., May, G. E., Marais, R., Perkins, G. R., Marshall, C. J., Cowley, S., and Enver, T. (1995) J. Biol. Chem. 270, 4101-4107
56. Hahm, K., Ernst, P., Lo, K., Kim, G. S., Turck, C., and Smale, S. T. (1994) Mol. Cell. Biol. 14, 7111-7123
57. Sassone-Corsi, P. (1998) Int. J. Biochem. Cell Biol. 30, 27-38
58. Ladias, J. A., and Karathanasis, S. K. (1991) Science 251, 561-565
59. Horvath, C. M., and Darnell, J. E. (1997) Curr. Opin. Cell Biol. 9, 233-239
60. Massague, J. (1996) Cell 85, 947-950
61. Laiho, M., DeCaprio, J. A., Ludlow, J. W., Livingston, D. M., and Massague, J. (1990) Cell 62, 175-185
62. de Winter, J. P., Roelen, B. A., ten Dijke, P., van der Burg, B., and van den Eijnden-van Raaij, A. J. (1997) Oncogene 14, 1891-1899
63. Katayose, D., Gudas, J., Nguyen, H., Srivastava, S., Cowan, K. H., and Seth, P. (1995) Clin. Cancer Res. 1, 889-897
64. Datto, M. B., Li, Y., Panus, J. F., Howe, D. J., Xiong, Y., and Wang, X. F. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5545-5549
65. Chen, H., Tritton, T. R., Kenny, N., Absher, M., and Chiu, J. F. (1996) J. Cell. Biochem. 61, 9-17
66. Choi, K. S., Lim, I. K., Brady, J. N., and Kim, S. J. (1998) Hepatology 27, 415-421
67. Chiao, P. J., Hunt, K. K., Grau, A. M., Abramian, A., Fleming, J., Zhang, W., Breslin, T., Abbruzzese, J. L., and Evans, D. B. (1999) Ann. N. Y. Acad. Sci. 880, 31-37
68. Lowe, S. W. (1995) Curr. Opin. Oncol. 7, 547-553
69. Frenkel, J., Sherman, D., Fein, A., Schwartz, D., Almog, N., Kapon, A., Goldfinger, N., and Rotter, V. (1999) Oncogene 18, 2901-2907
70. Williams, G. T., and Smith, C. A. (1993) Cell 74, 777-779
71. White, E. (1996) Genes Dev. 10, 1-15
72. Massague, J., and Weis-Garcia, F. (1996) Cancer Surv. 27, 41-64
73. Heldin, C. H., Miyazono, K., and ten Dijke, P. (1997) Nature 390, 465-471
74. Kretzschmar, M., and Massague, J. (1998) Curr. Opin. Genet. Dev. 8, 103-111
75. Lagna, G., Hata, A., Hemmati-Brivanlou, A., and Massague, J. (1996) Nature 383, 832-836
76. Zhang, Y., Musci, T., and Derynck, R. (1997) Curr. Biol. 7, 270-276
77. Liu, F., Pouponnot, C., and Massague, J. (1997) Genes Dev. 11, 3157-3167
78. Datto, M. B., Yu, Y., and Wang, X. F. (1995) J. Biol. Chem. 270, 28623-28628
79. Hu, P. P., Shen, X., Huang, D., Liu, Y., Counter, C., and Wang, X. F. (1999) J. Biol. Chem. 274, 35381-35387
80. Schutte, M., Hruban, R. H., Hedrick, L., Cho, K. R., Nadasdy, G. M., Weinstein, C. L., Bova, G. S., Isaacs, W. B., Cairns, P., Nawroz, H., Sidransky, D., Casero, R. A., Jr., Meltzer, P. S., Hahn, S. A., and Kern, S. E. (1996) Cancer Res. 56, 2527-2530
81. Hishikawa, K., Oemar, B. S., Tanner, F. C., Nakaki, T., Luscher, T. F., and Fujii, T. (1999) J. Biol. Chem. 274, 37461-37466
82. Hocevar, B. A., Brown, T. L., and Howe, P. H. (1999) EMBO J. 18, 1345-1356
83. Derynck, R., Zhang, Y., and Feng, X. H. (1998) Cell 95, 737-740
84. Kharbanda, S., Saxena, S., Yoshida, K., Pandey, P., Kaneki, M., Wang, Q., Cheng, K., Chen, Y. N., Campbell, A., Sudha, T., Yuan, Z. M., Narula, J., Weichselbaum, R., Nalin, C., and Kufe, D. (2000) J. Biol. Chem. 275, 322-327
85. Rizk, N. P., Chang, M. Y., El Kouri, C., Seth, P., Kaiser, L. R., Albelda, S. M., and Amin, K. M. (1999) Cancer Gene Ther. 6, 291-301
86. Frank, D. K., Frederick, M. J., Liu, T. J., and Clayman, G. L. (1998) Clin. Cancer Res. 4, 2521-2528