Melampomagnolide B: A new antileukemic sesquiterpene

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 4, 2011, Pages 1515-1519

  Nasim, Shama ^a   Pei, Shanshan ^b   Hagen, Fred K ^b   Jordan, Craig T ^b   Crooks, Peter A ^a  

^a University of Kentucky   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Antileukemic; Biotin conjugate; Melampomagnolide B; NF B inhibitor; Sesquiterpene

Indexed keywords

14 (N FLUORENYLMETHYLOXYCARBONYL 12 AMINODODECANOXY)MELAMPOMAGNOLIDE B; 14 [N (BIOTINYL) 12 AMINODODECANOXY]MELAMPOMAGNOLIDE B; ANTILEUKEMIC AGENT; MELAMPOMAGNOLIDE B; SESQUITERPENE DERIVATIVE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL TYPE; CHEMICAL INTERACTION; CONTROLLED STUDY; DRUG DESIGN; DRUG SELECTIVITY; DRUG SYNTHESIS; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL;

ANTINEOPLASTIC AGENTS; CELL SURVIVAL; HUMANS; LEUKEMIA; MOLECULAR STRUCTURE; SESQUITERPENES; TUMOR CELLS, CULTURED;

EID: 79951554165     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.12.045     Document Type: Article

References (16)

1. J. Skalska, P.S. Brookes, S.M. Nadtochiy, S.P. Hilchey, C.T. Jordan, M.L. Guzman, S.B. Maggirwar, M.M. Briehl, and S.H. Bernstein PLoS ONE 4 2009 e8115
2. P.M. Bork, M.L. Schmitz, M. Kuhnt, C. Escher, and M. Heinrich FEBS Lett. 402 1997 85
3. J. Wen, K.R. You, S.Y. Lee, C.H. Song, and D.G. Kim J. Biol. Chem. 277 2002 38954
4. S.P. Hehner, M. Heinrich, P.M. Bork, M. Vogt, F. Ratter, V. Lehmann, K. Schulze-Osthoff, W. Dröge, and M.L. Schmitz J. Biol. Chem. 273 1998 1288
5. C.J. Sweeney, L. Li, R. Shanmugam, P.B. Bhat-Nakshatri, V. Jayaprakasan, L.A. Baldridge, T. Gardner, M. Smith, H. Nakshatri, and L. Cheng Clin. Cancer Res. 10 2004 5501
6. M.T. Yip-Schneider, H. Nakshatri, C.J. Sweeney, M.S. Marshall, E.A. Wiebke, and C.M. Schmidt Mol. Cancer Ther. 4 2005 587
7. S. Nozaki, G.W. Sledge, and H. Nakshatri Oncogene 20 2001 2178
8. M.L. Guzman, R.M. Rossi, L. Karnischky, X. Li, D.R. Peterson, D.S. Howard, and C.T. Jordan Blood 105 2005 4163
9. M.L. Guzman, and C.T. Jordan Expert Opin. Biol. Ther. 5 2005 1147
10. S. Neelakantan, S. Nasim, M.L. Guzman, C.T. Jordan, and P.A. Crooks Bioorg. Med. Chem. Lett. 19 2009 4346
11. S. Nasim, and P.A. Crooks Bioorg. Med. Chem. Lett. 18 2008 3870
12. F.S. El-Feraly Phytochemistry 23 1984 2372
13. F.A. Macias, J.C.G. Galindo, and M.M. Guillermo Phytochemistry 31 1992 969
14. A.G. Gonzalez, A. Galindo, M. Mar Afonso, H. Mansilla, and M. Lopez Tetrahedron 44 1988 4585
15. B.H.B. Kwok, B. Koh, M.I. Ndubuisi, M. Elofsson, and C.M. Crews Chem. Biol. 8 2001 759
16. S.P. Hehner, T.G. Hofmann, W. Droge, and M.L. Schmitz J. Immunol. 163 1999 5617