Epigenetic regulation of spinal cxcr2 signaling in incisional hypersensitivity in mice

Anesthesiology

Volumn 119, Issue 5, 2013, Pages 1198-1208

  Sun, Yuan ^a   Sahbaie, Peyman ^a   Liang, De Yong ^a   Li, Wen Wu ^a   Li, Xiang Qi ^a   Shi, Xiao You ^a   Clark, J David ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE H3; LYSINE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EPIGENETICS; GENE EXPRESSION REGULATION; HEAT SENSITIVITY; HINDLIMB; HISTONE ACETYLATION; HYPERALGESIA; INCISION; MALE; MOUSE; NEUROPATHOLOGY; NOCICEPTION; NONHUMAN; PAIN RECEPTOR; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RNA ANALYSIS; SENSITIZATION; SIGNAL TRANSDUCTION; SPINAL CORD;

ANACARDIC ACIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; DINOPROSTONE; ENZYME INHIBITORS; EPIGENESIS, GENETIC; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INTRAOPERATIVE PERIOD; MALE; MICE; MICE, INBRED C57BL; NOCICEPTION; PAIN MEASUREMENT; PHENYLUREA COMPOUNDS; PHYSICAL STIMULATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-8B; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84888299549     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31829ce340     Document Type: Article

References (48)

1. Klose RJ, Bird AP: Genomic DNA methylation: The mark and its mediators. Trends Biochem Sci 2006; 31:89-7
2. Kouzarides T: Chromatin modifications and their function. Cell 2007; 128:693-705
3. Hsieh J, Gage FH: Epigenetic control of neural stem cell fate. Curr Opin Genet Dev 2004; 14:461-9
4. Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze SH, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG: Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science 2002; 298:1747-52
5. Hockly E, Richon VM, Woodman B, Smith DL, Zhou X, Rosa E, Sathasivam K, Ghazi-Noori S, Mahal A, Lowden PA, Steffan JS, Marsh JL, Thompson LM, Lewis CM, Marks PA, Bates GP: Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc Natl Acad Sci U S A 2003; 100:2041-6
6. Hoshino M, Tagawa K, Okuda T, Murata M, Oyanagi K, Arai N, Mizutani T, Kanazawa I, Wanker EE, Okazawa H: Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein. J Neurochem 2003; 87:257-67
7. Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM: Histone deacetylase inhibitors arrest polyglutaminedependent neurodegeneration in Drosophila. Nature 2001; 413:739-43
8. Peixoto L, Abel T: The role of histone acetylation in memory formation and cognitive impairments. Neuropsychopharmacology 2013; 38:62-6
9. Sultan FA, Day JJ: Epigenetic mechanisms in memory and synaptic function. Epigenomics 2011; 3:157-81
10. Pascual M, Do Couto BR, Alfonso-Loeches S, Aguilar MA, Rodriguez-Arias M, Guerri C: Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning. Neuropharmacology 2012; 62:2309-19
11. Wang L, Lv Z, Hu Z, Sheng J, Hui B, Sun J, Ma L: Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement. Neuropsychopharmacology 2010; 35:913-28
12. Bai G, Wei D, Zou S, Ren K, Dubner R: Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia. Mol Pain 2010; 6:51
13. Kiguchi N, Kobayashi Y, Maeda T, Fukazawa Y, Tohya K, Kimura M, Kishioka S: Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain. J Pharmacol Exp Ther 2012; 340:577-87
14. Zhang Z, Cai YQ, Zou F, Bie B, Pan ZZ: Epigenetic suppression of GAD65 expression mediates persistent pain. Nat Med 2011; 17:1448-55
15. Chiechio S, Zammataro M, Morales ME, Busceti CL, Drago F, Gereau RW IV, Copani A, Nicoletti F: Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain. Mol Pharmacol 2009; 75:1014-20
16. Brennan TJ: Incisional sensitivity and pain measurements: Dissecting mechanisms for postoperative pain. Anesthesiology 2005; 103:3-4
17. Katancik JA, Sharma A, de Nardin E: Interleukin 8, neutrophil-activating peptide-2 and GRO-alpha bind to and elicit cell activation via specific and different amino acid residues of CXCR2. Cytokine 2000; 12:1480-8
18. Carreira EU, Carregaro V, Teixeira MM, Moriconi A, Aramini A, Verri WA Jr, Ferreira SH, Cunha FQ, Cunha TM: Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. Eur J Pain 2013; 17:654-63
19. Manjavachi MN, Quintão NL, Campos MM, Deschamps IK, Yunes RA, Nunes RJ, Leal PC, Calixto JB: The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice. Eur J Pain 2010; 14:23-1
20. Clark JD, Shi X, Li X, Qiao Y, Liang D, Angst MS, Yeomans DC: Morphine reduces local cytokine expression and neutrophil infiltration after incision. Mol Pain 2007; 3:28
21. Clark JD, Qiao Y, Li X, Shi X, Angst MS, Yeomans DC: Blockade of the complement C5a receptor reduces incisional allodynia, edema, and cytokine expression. Anesthesiology 2006; 104:1274-82
22. Liang DY, Li X, Shi X, Sun Y, Sahbaie P, Li WW, Clark JD: The complement component C5a receptor mediates pain and inflammation in a postsurgical pain model. Pain 2012; 153:366-72
23. Sun Y, Li XQ, Sahbaie P, Shi XY, Li WW, Liang DY, Clark JD: miR-203 regulates nociceptive sensitization after incision by controlling phospholipase A2 activating protein expression. Anesthesiology 2012; 117:626-38
24. Liang DY, Li X, Clark JD: Epigenetic regulation of opioidinduced hyperalgesia, dependence, and tolerance in mice. J Pain 2013; 14:36-7
25. Colussi C, Rosati J, Straino S, Spallotta F, Berni R, Stilli D, Rossi S, Musso E, Macchi E, Mai A, Sbardella G, Castellano S, Chimenti C, Frustaci A, Nebbioso A, Altucci L, Capogrossi MC, Gaetano C: N?-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart. Proc Natl Acad Sci U S A 2011; 108:2795-800
26. Asiedu MN, Tillu DV, Melemedjian OK, Shy A, Sanoja R, Bodell B, Ghosh S, Porreca F, Price TJ: Spinal protein kinase M ? underlies the maintenance mechanism of persistent nociceptive sensitization. J Neurosci 2011; 31:6646-53
27. Li X, Shi X, Liang DY, Clark JD: Spinal CK2 regulates nociceptive signaling in models of inflammatory pain. Pain 2005; 115:182-90
28. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL: Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 1994; 53:55-3
29. Poree LR, Guo TZ, Kingery WS, Maze M: The analgesic potency of dexmedetomidine is enhanced after nerve injury: A possible role for peripheral alpha2-adrenoceptors. Anesth Analg 1998; 87:941-8
30. Hargreaves K, Dubner R, Brown F, Flores C, Joris J: A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988; 32:77-8
31. Sun Y, Fujigaki Y, Sakakima M, Fujikura T, Togawa A, Huang Y, Hishida A: Acquired resistance to rechallenge injury in rats that recovered from mild renal damage induced by uranyl acetate: Accelerated proliferation and hepatocyte growth factor/c-Met axis. Clin Exp Nephrol 2011; 15:666-75
32. Reichling DB, Levine JD: Critical role of nociceptor plasticity in chronic pain. Trends Neurosci 2009; 32:611-8
33. Levenson JM, Sweatt JD: Epigenetic mechanisms in memory formation. Nat Rev Neurosci 2005; 6:108-18
34. Renthal W, Nestler EJ: Epigenetic mechanisms in drug addiction. Trends Mol Med 2008; 14:341-50
35. Kazantsev AG, Thompson LM: Therapeutic application of histone deacetylase inhibitors for central nervous system disorders. Nat Rev Drug Discov 2008; 7:854-68
36. Gao YJ, Zhang L, Samad OA, Suter MR, Yasuhiko K, Xu ZZ, Park JY, Lind AL, Ma Q, Ji RR: JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J Neurosci 2009; 29:4096-108
37. Wilson NM, Jung H, Ripsch MS, Miller RJ, White FA: CXCR4 signaling mediates morphine-induced tactile hyperalgesia. Brain Behav Immun 2011; 25:565-73
38. Abbadie C, Bhangoo S, De Koninck Y, Malcangio M, Melik-Parsadaniantz S, White FA: Chemokines and pain mechanisms. Brain Res Rev 2009; 60:125-34
39. Zhu XY, Huang CS, Li Q, Chang RM, Song ZB, Zou WY, Guo QL: p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI). Mol Pain 2012; 8:84
40. Brennan TJ, Zahn PK, Pogatzki-Zahn EM: Mechanisms of incisional pain. Anesthesiol Clin North America 2005; 23:1-20
41. Prochazkova M, Dolezal T, Sliva J, Krsiak M: Different patterns of spinal cyclooxygenase-1 and cyclooxygenase-2 mRNA expression in inflammatory and postoperative pain. Basic Clin Pharmacol Toxicol 2006; 99:173-7
42. Giannini G, Cabri W, Fattorusso C, Rodriquez M: Histone deacetylase inhibitors in the treatment of cancer: Overview and perspectives. Future Med Chem 2012; 4:1439-60
43. Bogen O, Alessandri-Haber N, Chu C, Gear RW, Levine JD: Generation of a pain memory in the primary afferent nociceptor triggered by PKC? activation of CPEB. J Neurosci 2012; 32:2018-26
44. Wolter S, Doerrie A, Weber A, Schneider H, Hoffmann E, von der Ohe J, Bakiri L, Wagner EF, Resch K, Kracht M: c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol 2008; 28:4407-23
45. Peters CM, Eisenach JC: Contribution of the chemokine (C-C motif) ligand 2 (CCL2) to mechanical hypersensitivity after surgical incision in rats. Anesthesiology 2010; 112:1250-8
46. Iida S, Watanabe-Fukunaga R, Nagata S, Fukunaga R: Essential role of C/EBPalpha in G-CSF-induced transcriptional activation and chromatin modification of myeloid-specific genes. Genes Cells 2008; 13:313-27
47. Puma C, Danik M, Quirion R, Ramon F, Williams S: The chemokine interleukin-8 acutely reduces Ca(2+) currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs. J Neurochem 2001; 78:960-71
48. Mogil JS: Pain genetics: Past, present and future. Trends Genet 2012; 28:258-66