Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain

European Journal of Pain (United Kingdom)

Volumn 17, Issue 5, 2013, Pages 654-663

  Carreira, E U ^a   Carregaro, V ^a   Teixeira, M M ^b   Moriconi, A ^c   Aramini, A ^c   Verri, W A ^d   Ferreira, S H ^a   Cunha, F Q ^a   Cunha, T M ^a  

^a UNIVERSITY OF RIBEIRÃO PRETO   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c Chemistry Section   (Italy)

^d STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; GRANULOCYTE ANTIBODY; LADARIXIN; MYELOPEROXIDASE; VINBLASTINE SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MODEL; HYPERALGESIA; INCISION; MALE; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 84879574318     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1002/j.1532-2149.2012.00240.x     Document Type: Article

References (51)

1. Banik, R.K., Brennan, T.J. (2004). Spontaneous discharge and increased heat sensitivity of rat C-fiber nociceptors are present in vitro after plantar incision. Pain 112, 204-213.
2. Banik, R.K., Subieta, A.R., Wu, C., Brennan, T.J. (2005). Increased nerve growth factor after rat plantar incision contributes to guarding behavior and heat hyperalgesia. Pain 117, 68-76.
3. Bertini, R., Barcelos, L.S., Beccari, A.R., Cavalieri, B., Moriconi, A., Bizzarri, C., Di Benedetto, P., Di Giacinto, C., Gloaguen, I., Galliera, E., Corsi, M.M., Russo, R.C., Andrade, S.P., Cesta, M.C., Nano, G., Aramini, A., Cutrin, J.C., Locati, M., Allegretti, M., Teixeira, M.M. (2012). Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor. Br J Pharmacol 165, 436-454.
4. Castro, M.S.A., Ferreira, S.H. (1979). Cell migration and hyperalgesia: A paradoxical effect of endotoxin. In Advances in Inflammation Research, G. Weissmann, ed. (New York: Raven Press) pp. 311-316.
5. Chou, R.C., Kim, N.D., Sadik, C.D., Seung, E., Lan, Y., Byrne, M.H., Haribabu, B., Iwakura, Y., Luster, A.D. (2010). Lipidcytokine- chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis. Immunity 33, 266- 278.
6. Clark, J.D., Qiao, Y., Li, X., Shi, X., Angst, M.S., Yeomans, D.C. (2006). Blockade of the complement C5a receptor reduces incisional allodynia, edema, and cytokine expression. Anesthesiology 104, 1274-1282.
7. Clark, J.D., Shi, X., Li, X., Qiao, Y., Liang, D., Angst, M.S., Yeomans, D.C. (2007). Morphine reduces local cytokines expression and neutrophil infiltration after incision. Mol Pain 3, 28.
8. Cunha, T.M., Barsante, M.M., Guerrero, A.T., Verri, W.A., Jr Ferreira, S.H., Coelho, F.M., Bertini, R., Di Giacinto, C., Allegretti, M., Cunha, F.Q., Teixeira, M.M. (2008a). Treatment with DF 2162, a non-competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice. Br J Pharmacol 154, 460-470.
9. Cunha, T.M., Dal-Secco, D., Verri, W.A., Jr Guerrero, A.T., Souza, G.R., Vieira, S.M., Lotufo, C.M., Neto, A.F., Ferreira, S.H., Cunha, F.Q. (2008b). Dual role of hydrogen sulfide in mechanical inflammatory hypernociception. Eur J Pharmacol 590, 127-135.
10. Cunha, T.M., Verri, W.A., Jr Schivo, I.R., Napimoga, M.H., Parada, C.A., Poole, S., Teixeira, M.M., Ferreira, S.H., Cunha, F.Q. (2008c). Crucial role of neutrophils in the development of mechanical inflammatory hypernociception. J Leukoc Biol 83, 824-832.
11. Cunha, T.M., Verri, W.A., Jr Silva, J.S., Poole, S., Cunha, F.Q., Ferreira, S.H. (2005). A cascade of cytokines mediates mechanical inflammatory hypernociception in mice. Proc Natl Acad Sci U S A 102, 1755-1760.
12. Cunha, T.M., Verri, W.A., Jr Vivancos, G.G., Moreira, I.F., Reis, S., Parada, C.A., Cunha, F.Q., Ferreira, S.H. (2004). An electronic pressure-meter nociception paw test for mice. Braz J Med Biol Res 37, 401-407.
13. Endlich, B., Armstrong, D., Brodsky, J., Novotny, M., Hamilton, T.A. (2002). Distinct temporal patterns of macrophageinflammatory protein-2 and KC chemokine gene expression in surgical injury. J Immunol 168, 3586-3594.
14. Eyles, J.L., Roberts, A.W., Metcalf, D., Wicks, I.P. (2006). Granulocyte colony-stimulating factor and neutrophils - Forgotten mediators of inflammatory disease. Nat Clin Pract Rheumatol 2, 500-510.
15. Fernandez-Patron, C., Zouki, C., Whittal, R., Chan, J.S., Davidge, S.T., Filep, J.G. (2001). Matrix metalloproteinases regulate neutrophil-endothelial cell adhesion through generation of endothelin-1. FASEB J 15, 2230-2240.
16. Foxman, E.F., Campbell, J.J., Butcher, E.C. (1997). Multistep navigation and the combinatorial control of leukocyte chemotaxis. J Cell Biol 139, 1349-1360.
17. Garau, A., Bertini, R., Mosca, M., Bizzarri, C., Anacardio, R., Triulzi, S., Allegretti, M., Ghezzi, P., Villa, P. (2006). Development of a systemically-active dual CXCR1/CXCR2 allosteric inhibitor and its efficacy in a model of transient cerebral ischemia in the rat. Eur Cytokine Netw 17, 35-41.
18. Grespan, R., Fukada, S.Y., Lemos, H.P., Vieira, S.M., Napimoga, M.H., Teixeira, M.M., Fraser, A.R., Liew, F.Y., McInnes, I.B., Cunha, F.Q. (2008). CXCR2-specific chemokines mediate leukotriene B4-dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis. Arthritis Rheum 58, 2030-2040.
19. Guerrero, A.T., Verri, W.A., Jr Cunha, T.M., Silva, T.A., Schivo, I.R., Dal-Secco, D., Canetti, C., Rocha, F.A., Parada, C.A., Cunha, F.Q., Ferreira, S.H. (2008). Involvement of LTB4 in zymosan-induced joint nociception in mice: Participation of neutrophils and PGE2. J Leukoc Biol 83, 122-130.
20. Hestdal, K., Ruscetti, F.W., Ihle, J.N., Jacobsen, S.E., Dubois, C.M., Kopp, W.C., Longo, D.L., Keller, J.R. (1991). Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. J Immunol 147, 22-28.
21. Hu, Y., Liang, D., Li, X., Liu, H.H., Zhang, X., Zheng, M., Dill, D., Shi, X., Qiao, Y., Yeomans, D., Carvalho, B., Angst, M.S., Clark, J.D., Peltz, G. (2010). The role of interleukin-1 in wound biology. Part I: Murine in silico and in vitro experimental analysis. Anesth Analg 111, 1525-1533.
22. Jang, J.H., Liang, D., Kido, K., Sun, Y., Clark, D.J., Brennan, T.J. (2011). Increased local concentration of complement C5a contributes to incisional pain in mice. J Neuroinflammation 8, 80.
23. Kang, S., Brennan, T.J. (2009). Chemosensitivity and mechanosensitivity of nociceptors from incised rat hindpaw skin. Anesthesiology 111, 155-164.
24. Kasama, T., Miwa, Y., Isozaki, T., Odai, T., Adachi, M., Kunkel, S.L. (2005). Neutrophil-derived cytokines: Potential therapeutic targets in inflammation. Curr Drug Targets Inflamm Allergy 4, 273-279.
25. Lavich, T.R., Siqueira Rde, A., Farias-Filho, F.A., Cordeiro, R.S., Rodrigues E Silva, P.M., Martins, M.A. (2006). Neutrophil infiltration is implicated in the sustained thermal hyperalgesic response evoked by allergen provocation in actively sensitized rats. Pain 125, 180-187.
26. Levine, J.D., Gooding, J., Donatoni, P., Borden, L., Goetzl, E.J. (1985). The role of the polymorphonuclear leukocyte in hyperalgesia. J Neurosci 5, 3025-3029.
27. Liang, D.Y., Li, X., Shi, X., Sun, Y., Sahbaie, P., Li, W.W., Clark, J.D. (2012). The complement component C5a receptor mediates pain and inflammation in a postsurgical pain model. Pain 153, 366-372.
28. Motta, E.M., Calixto, J.B., Rae, G.A. (2009). Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases. Exp Biol Med 231, 1141-1145.
29. Mujenda, F.H., Duarte, A.M., Reilly, E.K., Strichartz, G.R. (2007). Cutaneous endothelin-A receptors elevate postincisional pain. Pain 133, 161-173.
30. Palmer, G., Gabay, C., Imhof, B.A. (2006). Leukocyte migration to rheumatoid joints: Enzymes take over. Arthritis Rheum 54, 2707-2710.
31. Perkins, N.M., Tracey, D.J. (2000). Hyperalgesia due to nerve injury: Role of neutrophils. Neuroscience 101, 745-757.
32. Phillipson, M., Kubes, P. (2011). The neutrophil in vascular inflammation. Nat Med 17, 1381-1390.
33. Pinto, L.G., Cunha, T.M., Vieira, S.M., Lemos, H.P., Verri, W.A., Jr Cunha, F.Q., Ferreira, S.H. (2010). IL-17 mediates articular hypernociception in antigen-induced arthritis in mice. Pain 148, 247-256.
34. Pogatzki, E.M., Gebhart, G.F., Brennan, T.J. (2002). Characterization of Adelta- and C-fibers innervating the plantar rat hindpaw one day after an incision. J Neurophysiol 87, 721-731.
35. Raeburn, C.D., Dinarello, C.A., Zimmerman, M.A., Calkins, C.M., Pomerantz, B.J., McIntyre, R.C., Jr Harken, A.H., Meng, X. (2002). Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction. Am J Physiol Heart Circ Physiol 283, H650-H657.
36. Reutershan, J., Morris, M.A., Burcin, T.L., Smith, D.F., Chang, D., Saprito, M.S., Ley, K. (2006). Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung. J Clin Invest 116, 695-702.
37. Sadik, C.D., Kim, N.D., Luster, A.D. (2011). Neutrophils cascading their way to inflammation. Trends Immunol 32, 452-460.
38. Sahbaie, P., Shi, X., Guo, T.Z., Qiao, Y., Yeomans, D.C., Kingery, W.S., Clark, J.D. (2009). Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision. Pain 145, 341-349.
39. Sanz, M.J., Kubes, P. (2012). Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking. Eur J Immunol 42, 278- 283.
40. Segal, A.W. (2005). How neutrophils kill microbes. Annu Rev Immunol 23, 197-223.
41. Steen, K.H., Reeh, P.W., Anton, F., Handwerker, H.O. (1992). Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci 12, 86-95.
42. Stillie, R., Farooq, S.M., Gordon, J.R., Stadnyk, A.W. (2009). The functional significance behind expressing two IL-8 receptor types on PMN. J Leukoc Biol 86, 529-543.
43. Ting, E., Guerrero, A.T., Cunha, T.M., Verri, W.A., Jr Taylor, S.M., Woodruff, T.M., Cunha, F.Q., Ferreira, S.H. (2008). Role of complement C5a in mechanical inflammatory hypernociception: Potential use of C5a receptor antagonists to control inflammatory pain. Br J Pharmacol 153, 1043-1053.
44. Verri, W.A., Jr Cunha, T.M., Magro, D.A., Guerrero, A.T., Vieira, S.M., Carregaro, V., Souza, G.R., Henriques, M.G., Ferreira, S.H., Cunha, F.Q. (2009). Targeting endothelin ETA and ETB receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice. Naunyn Schmiedebergs Arch Pharmacol 379, 271-279.
45. Vieira, S.M., Lemos, H.P., Grespan, R., Napimoga, M.H., Dal- Secco, D., Freitas, A., Cunha, T.M., Verri, W.A. Jr., Souza- Junior, D.A., Jamur, M.C., Fernandes, K.S., Oliver, C., Silva, J.S., Teixeira, M.M., Cunha, F.Q. (2009). A crucial role for TNF-alpha in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5. Br J Pharmacol 158, 779-789.
46. Wang, Z.Q., Porreca, F., Cuzzocrea, S., Galen, K., Lightfoot, R., Masini, E., Muscoli, C., Mollace, V., Ndengele, M., Ischiropoulos, H., Salvemini, D. (2004). A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther 309, 869-878.
47. Williams, M.R., Azcutia, V., Newton, G., Alcaide, P., Luscinskas, F.W. (2011). Emerging mechanisms of neutrophil recruitment across endothelium. Trends Immunol 32, 461-469.
48. Wolf, G., Livshits, D., Beilin, B., Yirmiya, R., Shavit, Y. (2008). Interleukin-1 signaling is required for induction and maintenance of postoperative incisional pain: Genetic and pharmacological studies in mice. Brain Behav Immun 22, 1072-1077.
49. Woo, Y.C., Park, S.S., Subieta, A.R., Brennan, T.J. (2004). Changes in tissue pH and temperature after incision indicate acidosis may contribute to postoperative pain. Anesthesiology 101, 468-475.
50. Wu, C., Boustany, L., Liang, H., Brennan, T.J. (2007). Nerve growth factor expression after plantar incision in the rat. Anesthesiology 107, 128-135.
51. Xu, J., Brennan, T.J. (2011). The pathophysiology of acute pain: Animal models. Curr Opin Anaesthesiol 24, 508-514.