The analgesic potency of dexmedetomidine is enhanced after nerve injury: A possible role for peripheral α2-adrenoceptors

Anesthesia and Analgesia

Volumn 87, Issue 4, 1998, Pages 941-948

  Poree, Lawrence R ^a,b,c   Guo, Tian Z ^a,b   Kingery, Wade S ^a,b   Maze, Mervyn ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ATIPAMEZOLE; DEXMEDETOMIDINE; N [2 (1,3,4,6,7,12B HEXAHYDRO 2' OXOSPIRO[2H BENZOFURO[2,3 A]QUINOLIZINE 2,4' IMIDAZOLIDIN] 3' YL)ETHYL]METHANESULFONAMIDE; SODIUM CHLORIDE;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; HYPERALGESIA; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NERVE INJURY; NERVE LIGATION; NEURALGIA; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SEDATION; SPINAL NERVE; WITHDRAWAL REFLEX;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANALGESICS, NON-NARCOTIC; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; IMIDAZOLES; MALE; MEDETOMIDINE; PAIN; PAIN THRESHOLD; QUINOLIZINES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL NERVES;

EID: 0031690853     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199810000-00037     Document Type: Article

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