Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 3, 2012, Pages 577-587

  Kiguchi, Norikazu ^a   Kobayashi, Yuka ^a   Maeda, Takehiko ^b   Fukazawa, Yohji ^a,c   Tohya, Kazuo ^c   Kimura, Michio ^c   Kishioka, Shiroh ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^c KANSAI UNIVERSITY OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; ANACARDIC ACID; CHEMOKINE RECEPTOR CXCR2; CXCL2 CHEMOKINE; HISTONE H3; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; PROTEIN ANTIBODY;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; CXC CHEMOKINE RECEPTOR TYPE 2 GENE; EPIGENETICS; GENE; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC ANALYSIS; HISTONE ACETYLATION; HISTONE H3 GENE; HYPERALGESIA; MACROPHAGE ACTIVATION; MACROPHAGE INFLAMMATORY PROTEIN 2 GENE; MOLECULAR PATHOLOGY; MOUSE; NERVE LIGATION; NEUROMODULATION; NEUROPATHIC PAIN; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL GRANULE; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCIATIC NERVE; UPREGULATION;

ACETYLATION; ANIMALS; CHEMOKINE CXCL2; EPIGENESIS, GENETIC; HISTONES; MALE; MICE; MICE, INBRED ICR; NEURALGIA; NEUTROPHIL INFILTRATION; PERIPHERAL NERVE INJURIES; PROMOTER REGIONS, GENETIC; RECEPTORS, INTERLEUKIN-8B;

EID: 84857315556     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.187724     Document Type: Article

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