Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

Blood

Volumn 116, Issue 25, 2010, Pages 5443-5454

  Jeannet, Robin ^a   Mastio, Jérôme ^a   Macias Garcia, Alejandra ^a   Oravecz, Attila ^a   Ashworth, Todd ^b   Geimer Le Lay, Anne Solen ^a   Jost, Bernard ^a   Le Gras, Stéphanie ^a   Ghysdael, Jacques ^c   Gridley, Thomas ^d   Honjo, Tasuku ^e   Radtke, Freddy ^f   Aster, Jon C ^b   Chan, Susan ^a   Kastner, Philippe ^a,g  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b HARVARD MEDICAL SCHOOL   (United States)

^c INSTITUT CURIE   (France)

^d JACKSON LABORATORY   (United States)

^e KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f EPFL   (Switzerland)

^g UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IKAROS TRANSCRIPTION FACTOR; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EPIGENETICS; EXON; GENE; GENE ACTIVATION; GENE DELETION; GENE LOCUS; LEUKEMOGENESIS; MOUSE; NONHUMAN; NOTCH1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION;

EID: 78650379575     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-05-286658     Document Type: Article

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