메뉴 건너뛰기




Volumn 31, Issue 8, 2013, Pages 1247-1259

In vivo phage display - A discovery tool in molecular biomedicine

Author keywords

Molecular medicine; Peptide identification; Phage library; Screening; Targeting

Indexed keywords

DRUG DEVELOPMENT; HETEROGENEOUS EXPRESSIONS; HIGH-THROUGHPUT METHOD; METHODOLOGICAL ASPECTS; MOLECULAR MEDICINE; PEPTIDE IDENTIFICATION; PHAGE LIBRARIES; TARGETING;

EID: 84887997651     PISSN: 07349750     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biotechadv.2013.04.004     Document Type: Review
Times cited : (55)

References (125)
  • 1
    • 13844315323 scopus 로고    scopus 로고
    • Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature
    • Akerman M.E., Pilch J., Peters D., Ruoslahti E. Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature. Proc Natl Acad Sci U S A 2005, 102:2040-2045.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2040-2045
    • Akerman, M.E.1    Pilch, J.2    Peters, D.3    Ruoslahti, E.4
  • 2
    • 33748325669 scopus 로고    scopus 로고
    • Identification of oligopeptides binding to peritoneal tumors of gastric cancer
    • Akita N., Maruta F., Seymour L.W., Kerr D.J., Parker A.L., Asai T., et al. Identification of oligopeptides binding to peritoneal tumors of gastric cancer. Cancer Sci 2006, 97:1075-1081.
    • (2006) Cancer Sci , vol.97 , pp. 1075-1081
    • Akita, N.1    Maruta, F.2    Seymour, L.W.3    Kerr, D.J.4    Parker, A.L.5    Asai, T.6
  • 3
    • 84859429437 scopus 로고    scopus 로고
    • Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium
    • Alva A., Slovin S., Daignault S., Carducci M., Dipaola R., Pienta K., et al. Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium. Invest New Drugs 2012, 30:749-757.
    • (2012) Invest New Drugs , vol.30 , pp. 749-757
    • Alva, A.1    Slovin, S.2    Daignault, S.3    Carducci, M.4    Dipaola, R.5    Pienta, K.6
  • 4
    • 0344324067 scopus 로고    scopus 로고
    • The human vascular mapping project. Selection and utilization of molecules for tumor endothelial targeting
    • Arap W., Pasqualini R. The human vascular mapping project. Selection and utilization of molecules for tumor endothelial targeting. Haemostasis 2001, 31:30-31.
    • (2001) Haemostasis , vol.31 , pp. 30-31
    • Arap, W.1    Pasqualini, R.2
  • 5
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • Arap W., Pasqualini R., Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998, 279:377-380.
    • (1998) Science , vol.279 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 7
    • 0027495481 scopus 로고
    • Recent advances in phage display
    • Barbas C.F. Recent advances in phage display. Curr Opin Biotechnol 1993, 4:526-530.
    • (1993) Curr Opin Biotechnol , vol.4 , pp. 526-530
    • Barbas, C.F.1
  • 8
    • 0025838021 scopus 로고
    • Assembly of combinatorial antibody libraries on phage surfaces: the gene III site
    • Barbas C.F., Kang A.S., Lerner R.A., Benkovic S.J. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc Natl Acad Sci U S A 1991, 88:7978-7982.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 7978-7982
    • Barbas, C.F.1    Kang, A.S.2    Lerner, R.A.3    Benkovic, S.J.4
  • 10
    • 0031582621 scopus 로고    scopus 로고
    • Protective immune responses induced by the immunization of mice with a recombinant bacteriophage displaying an epitope of the human respiratory syncytial virus
    • Bastien N., Trudel M., Simard C. Protective immune responses induced by the immunization of mice with a recombinant bacteriophage displaying an epitope of the human respiratory syncytial virus. Virology 1997, 234:118-122.
    • (1997) Virology , vol.234 , pp. 118-122
    • Bastien, N.1    Trudel, M.2    Simard, C.3
  • 12
    • 14844309606 scopus 로고    scopus 로고
    • Discovery of targeting peptides for selective therapy of medullary thyroid carcinoma
    • Bockmann M., Drosten M., Putzer B.M. Discovery of targeting peptides for selective therapy of medullary thyroid carcinoma. J Gene Med 2005, 7:179-188.
    • (2005) J Gene Med , vol.7 , pp. 179-188
    • Bockmann, M.1    Drosten, M.2    Putzer, B.M.3
  • 13
    • 0036583161 scopus 로고    scopus 로고
    • A novel strategy for the functional cloning of enzymes using filamentous phage display: the case of nucleotidyl transferases
    • Brunet E., Chauvin C., Choumet V., Jestin J.L. A novel strategy for the functional cloning of enzymes using filamentous phage display: the case of nucleotidyl transferases. Nucleic Acids Res 2002, 30:e40.
    • (2002) Nucleic Acids Res , vol.30
    • Brunet, E.1    Chauvin, C.2    Choumet, V.3    Jestin, J.L.4
  • 14
    • 0037017835 scopus 로고    scopus 로고
    • Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo
    • Buerkle M.A., Pahernik S.A., Sutter A., Jonczyk A., Messmer K., Dellian M. Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo. Br J Cancer 2002, 86:788-795.
    • (2002) Br J Cancer , vol.86 , pp. 788-795
    • Buerkle, M.A.1    Pahernik, S.A.2    Sutter, A.3    Jonczyk, A.4    Messmer, K.5    Dellian, M.6
  • 15
    • 34447512451 scopus 로고    scopus 로고
    • Targeting of human renal tumor-derived endothelial cells with peptides obtained by phage display
    • Bussolati B., Grange C., Tei L., Deregibus M.C., Ercolani M., Aime S., et al. Targeting of human renal tumor-derived endothelial cells with peptides obtained by phage display. J Mol Med 2007, 85:897-906.
    • (2007) J Mol Med , vol.85 , pp. 897-906
    • Bussolati, B.1    Grange, C.2    Tei, L.3    Deregibus, M.C.4    Ercolani, M.5    Aime, S.6
  • 16
    • 81255196236 scopus 로고    scopus 로고
    • Phage display peptide probes for imaging early response to bevacizumab treatment
    • Cao Q., Liu S., Niu G., Chen K., Yan Y., Liu Z., et al. Phage display peptide probes for imaging early response to bevacizumab treatment. Amino Acids 2011, 41:1103-1112.
    • (2011) Amino Acids , vol.41 , pp. 1103-1112
    • Cao, Q.1    Liu, S.2    Niu, G.3    Chen, K.4    Yan, Y.5    Liu, Z.6
  • 17
    • 67649683033 scopus 로고    scopus 로고
    • Antiangiogenic targeting liposomes increase therapeutic efficacy for solid tumors
    • Chang D.K., Chiu C.Y., Kuo S.Y., Lin W.C., Lo A., Wang Y.P., et al. Antiangiogenic targeting liposomes increase therapeutic efficacy for solid tumors. J Biol Chem 2009, 284:12905-12916.
    • (2009) J Biol Chem , vol.284 , pp. 12905-12916
    • Chang, D.K.1    Chiu, C.Y.2    Kuo, S.Y.3    Lin, W.C.4    Lo, A.5    Wang, Y.P.6
  • 18
    • 33645737723 scopus 로고    scopus 로고
    • Transdermal protein delivery by a coadministered peptide identified via phage display
    • Chen Y.P., Shen Y.Y., Guo X., Zhang C.S., Yang W.J., Ma M.L., et al. Transdermal protein delivery by a coadministered peptide identified via phage display. Nat Biotechnol 2006, 24:455-460.
    • (2006) Nat Biotechnol , vol.24 , pp. 455-460
    • Chen, Y.P.1    Shen, Y.Y.2    Guo, X.3    Zhang, C.S.4    Yang, W.J.5    Ma, M.L.6
  • 19
    • 0028911488 scopus 로고
    • Identification of biologically active peptides using random libraries displayed on phage
    • Cortese R., Monaci P., Nicosia A., Luzzago A., Felici F., Galfre G., et al. Identification of biologically active peptides using random libraries displayed on phage. Curr Opin Biotechnol 1995, 6:73-80.
    • (1995) Curr Opin Biotechnol , vol.6 , pp. 73-80
    • Cortese, R.1    Monaci, P.2    Nicosia, A.3    Luzzago, A.4    Felici, F.5    Galfre, G.6
  • 20
    • 14944353793 scopus 로고    scopus 로고
    • Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs
    • Corti A., Ponzoni M. Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs. Ann N Y Acad Sci 2004, 1028:104-112.
    • (2004) Ann N Y Acad Sci , vol.1028 , pp. 104-112
    • Corti, A.1    Ponzoni, M.2
  • 21
    • 0027723182 scopus 로고
    • Display of biologically active proteins on the surface of filamentous phages: a cDNA cloning system for selection of functional gene products linked to the genetic information responsible for their production
    • Crameri R., Suter M. Display of biologically active proteins on the surface of filamentous phages: a cDNA cloning system for selection of functional gene products linked to the genetic information responsible for their production. Gene 1993, 137:69-75.
    • (1993) Gene , vol.137 , pp. 69-75
    • Crameri, R.1    Suter, M.2
  • 22
    • 0033764170 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
    • Curnis F., Sacchi A., Borgna L., Magni F., Gasparri A., Corti A. Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol 2000, 18:1185-1190.
    • (2000) Nat Biotechnol , vol.18 , pp. 1185-1190
    • Curnis, F.1    Sacchi, A.2    Borgna, L.3    Magni, F.4    Gasparri, A.5    Corti, A.6
  • 23
    • 0036678474 scopus 로고    scopus 로고
    • Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
    • Curnis F., Sacchi A., Corti A. Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration. J Clin Invest 2002, 110:475-482.
    • (2002) J Clin Invest , vol.110 , pp. 475-482
    • Curnis, F.1    Sacchi, A.2    Corti, A.3
  • 24
    • 0033549864 scopus 로고    scopus 로고
    • N-methylated cyclic RGD peptides as highly active and selective alpha(v)beta(3) integrin antagonists
    • Dechantsreiter M.A., Planker E., Matha B., Lohof E., Holzemann G., Jonczyk A., et al. N-methylated cyclic RGD peptides as highly active and selective alpha(v)beta(3) integrin antagonists. J Med Chem 1999, 42:3033-3040.
    • (1999) J Med Chem , vol.42 , pp. 3033-3040
    • Dechantsreiter, M.A.1    Planker, E.2    Matha, B.3    Lohof, E.4    Holzemann, G.5    Jonczyk, A.6
  • 25
    • 34548070176 scopus 로고    scopus 로고
    • Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p
    • Denby L., Work L.M., Von Seggern D.J., Wu E., McVey J.H., Nicklin S.A., et al. Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p. Mol Ther 2007, 15:1647-1654.
    • (2007) Mol Ther , vol.15 , pp. 1647-1654
    • Denby, L.1    Work, L.M.2    Von Seggern, D.J.3    Wu, E.4    McVey, J.H.5    Nicklin, S.A.6
  • 26
    • 84862489781 scopus 로고    scopus 로고
    • By-passing large screening experiments using sequencing as a tool to identify scFv fragments targeting atherosclerotic lesions in a novel in vivo phage display selection
    • Deramchia K., Jacobin-Valat M.J., Laroche-Traineau J., Bonetto S., Sanchez S., Dos Santos P., et al. By-passing large screening experiments using sequencing as a tool to identify scFv fragments targeting atherosclerotic lesions in a novel in vivo phage display selection. Int J Mol Sci 2012, 13:6902-6923.
    • (2012) Int J Mol Sci , vol.13 , pp. 6902-6923
    • Deramchia, K.1    Jacobin-Valat, M.J.2    Laroche-Traineau, J.3    Bonetto, S.4    Sanchez, S.5    Dos Santos, P.6
  • 27
    • 84861608801 scopus 로고    scopus 로고
    • In vivo phage display to identify new human antibody fragments homing to atherosclerotic endothelial and subendothelial tissues [corrected]
    • Deramchia K., Jacobin-Valat M.J., Vallet A., Bazin H., Santarelli X., Sanchez S., et al. In vivo phage display to identify new human antibody fragments homing to atherosclerotic endothelial and subendothelial tissues [corrected]. Am J Pathol 2012, 180:2576-2589.
    • (2012) Am J Pathol , vol.180 , pp. 2576-2589
    • Deramchia, K.1    Jacobin-Valat, M.J.2    Vallet, A.3    Bazin, H.4    Santarelli, X.5    Sanchez, S.6
  • 28
    • 77949528753 scopus 로고    scopus 로고
    • Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis
    • Dias-Neto E., Nunes D.N., Giordano R.J., Sun J., Botz G.H., Yang K., et al. Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis. PLoS One 2009, 4:e8338.
    • (2009) PLoS One , vol.4
    • Dias-Neto, E.1    Nunes, D.N.2    Giordano, R.J.3    Sun, J.4    Botz, G.H.5    Yang, K.6
  • 30
    • 1642524195 scopus 로고    scopus 로고
    • Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier
    • Duerr D.M., White S.J., Schluesener H.J. Identification of peptide sequences that induce the transport of phage across the gastrointestinal mucosal barrier. J Virol Methods 2004, 116:177-180.
    • (2004) J Virol Methods , vol.116 , pp. 177-180
    • Duerr, D.M.1    White, S.J.2    Schluesener, H.J.3
  • 31
    • 0347155579 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins alphavbeta3 and alphavbeta5 in patients with advanced solid tumours
    • Eskens F.A., Dumez H., Hoekstra R., Perschl A., Brindley C., Bottcher S., et al. Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins alphavbeta3 and alphavbeta5 in patients with advanced solid tumours. Eur J Cancer 2003, 39:917-926.
    • (2003) Eur J Cancer , vol.39 , pp. 917-926
    • Eskens, F.A.1    Dumez, H.2    Hoekstra, R.3    Perschl, A.4    Brindley, C.5    Bottcher, S.6
  • 33
    • 34247619887 scopus 로고    scopus 로고
    • An in vivo approach to structure activity relationship analysis of peptide ligands
    • Fan X.M., Venegas R., Fey R., van der Heyde H., Bernard M.A., Lazarides E., et al. An in vivo approach to structure activity relationship analysis of peptide ligands. Pharm Res 2007, 24:868-879.
    • (2007) Pharm Res , vol.24 , pp. 868-879
    • Fan, X.M.1    Venegas, R.2    Fey, R.3    van der Heyde, H.4    Bernard, M.A.5    Lazarides, E.6
  • 34
    • 33644673385 scopus 로고    scopus 로고
    • Laryngeal muscle surface receptors identified using random phage library
    • Flint P.W., Li Z.B., Lehar M., Saito K., Pai S.I. Laryngeal muscle surface receptors identified using random phage library. Laryngoscope 2005, 115:1930-1937.
    • (2005) Laryngoscope , vol.115 , pp. 1930-1937
    • Flint, P.W.1    Li, Z.B.2    Lehar, M.3    Saito, K.4    Pai, S.I.5
  • 35
    • 52049123781 scopus 로고    scopus 로고
    • Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma
    • Fogal V., Zhang L., Krajewski S., Ruoslahti E. Mitochondrial/cell-surface protein p32/gC1qR as a molecular target in tumor cells and tumor stroma. Cancer Res 2008, 68:7210-7218.
    • (2008) Cancer Res , vol.68 , pp. 7210-7218
    • Fogal, V.1    Zhang, L.2    Krajewski, S.3    Ruoslahti, E.4
  • 36
    • 0034732090 scopus 로고    scopus 로고
    • Immunisation with phage displaying peptides representing single epitopes of the glycoprotein G can give rise to partial protective immunity to HSV-2
    • Grabowska A.M., Jennings R., Laing P., Darsley M., Jameson C.L., Swift L., et al. Immunisation with phage displaying peptides representing single epitopes of the glycoprotein G can give rise to partial protective immunity to HSV-2. Virology 2000, 269:47-53.
    • (2000) Virology , vol.269 , pp. 47-53
    • Grabowska, A.M.1    Jennings, R.2    Laing, P.3    Darsley, M.4    Jameson, C.L.5    Swift, L.6
  • 37
    • 67650638995 scopus 로고    scopus 로고
    • Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours
    • Gregorc V., Santoro A., Bennicelli E., Punt C.J., Citterio G., Timmer-Bonte J.N., et al. Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours. Br J Cancer 2009, 101:219-224.
    • (2009) Br J Cancer , vol.101 , pp. 219-224
    • Gregorc, V.1    Santoro, A.2    Bennicelli, E.3    Punt, C.J.4    Citterio, G.5    Timmer-Bonte, J.N.6
  • 38
    • 77956414169 scopus 로고    scopus 로고
    • Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma
    • Gregorc V., Zucali P.A., Santoro A., Ceresoli G.L., Citterio G., De Pas T.M., et al. Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma. J Clin Oncol 2010, 28:2604-2611.
    • (2010) J Clin Oncol , vol.28 , pp. 2604-2611
    • Gregorc, V.1    Zucali, P.A.2    Santoro, A.3    Ceresoli, G.L.4    Citterio, G.5    De Pas, T.M.6
  • 39
    • 52949103737 scopus 로고    scopus 로고
    • Non-specific translocation of peptide-displaying bacteriophage particles across the gastrointestinal barrier
    • Hamzeh-Mivehroud M., Mahmoudpour A., Rezazadeh H., Dastmalchi S. Non-specific translocation of peptide-displaying bacteriophage particles across the gastrointestinal barrier. Eur J Pharm Biopharm 2008, 70:577-581.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 577-581
    • Hamzeh-Mivehroud, M.1    Mahmoudpour, A.2    Rezazadeh, H.3    Dastmalchi, S.4
  • 40
    • 34548175694 scopus 로고    scopus 로고
    • Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors
    • Hariharan S., Gustafson D., Holden S., McConkey D., Davis D., Morrow M., et al. Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrin receptor antagonist, cilengitide (EMD 121974), in patients with advanced solid tumors. Ann Oncol 2007, 18:1400-1407.
    • (2007) Ann Oncol , vol.18 , pp. 1400-1407
    • Hariharan, S.1    Gustafson, D.2    Holden, S.3    McConkey, D.4    Davis, D.5    Morrow, M.6
  • 41
    • 33746077510 scopus 로고    scopus 로고
    • Whole genome phage display selects for proline-rich Boi polypeptides against Bem1p
    • Hertveldt K., Robben J., Volckaert G. Whole genome phage display selects for proline-rich Boi polypeptides against Bem1p. Biotechnol Lett 2006, 28:1233-1239.
    • (2006) Biotechnol Lett , vol.28 , pp. 1233-1239
    • Hertveldt, K.1    Robben, J.2    Volckaert, G.3
  • 43
    • 27144432842 scopus 로고    scopus 로고
    • Engineered antibody fragments and the rise of single domains
    • Holliger P., Hudson P.J. Engineered antibody fragments and the rise of single domains. Nat Biotechnol 2005, 23:1126-1136.
    • (2005) Nat Biotechnol , vol.23 , pp. 1126-1136
    • Holliger, P.1    Hudson, P.J.2
  • 44
    • 54049101465 scopus 로고    scopus 로고
    • Detection of apoptosis in a rat model of focal cerebral ischemia using a homing peptide selected from in vivo phage display
    • Hong H.Y., Choi J.S., Kim Y.J., Lee H.Y., Kwak W., Yoo J., et al. Detection of apoptosis in a rat model of focal cerebral ischemia using a homing peptide selected from in vivo phage display. J Control Release 2008, 131:167-172.
    • (2008) J Control Release , vol.131 , pp. 167-172
    • Hong, H.Y.1    Choi, J.S.2    Kim, Y.J.3    Lee, H.Y.4    Kwak, W.5    Yoo, J.6
  • 45
    • 0035831081 scopus 로고    scopus 로고
    • Homing markers for atherosclerosis: applications for drug delivery, gene delivery and vascular imaging
    • Houston P., Goodman J., Lewis A., Campbell C.J., Braddock M. Homing markers for atherosclerosis: applications for drug delivery, gene delivery and vascular imaging. FEBS Lett 2001, 492:73-77.
    • (2001) FEBS Lett , vol.492 , pp. 73-77
    • Houston, P.1    Goodman, J.2    Lewis, A.3    Campbell, C.J.4    Braddock, M.5
  • 47
    • 33846907902 scopus 로고    scopus 로고
    • A novel peptide that selectively binds highly metastatic hepatocellular carcinoma cell surface is related to invasion and metastasis
    • Jia W.D., Sun H.C., Zhang J.B., Xu Y., Qian Y.B., Pang J.Z., et al. A novel peptide that selectively binds highly metastatic hepatocellular carcinoma cell surface is related to invasion and metastasis. Cancer Lett 2007, 247:234-242.
    • (2007) Cancer Lett , vol.247 , pp. 234-242
    • Jia, W.D.1    Sun, H.C.2    Zhang, J.B.3    Xu, Y.4    Qian, Y.B.5    Pang, J.Z.6
  • 48
    • 0034717218 scopus 로고    scopus 로고
    • In vivo selection of sFv from phage display libraries
    • Johns M., George A.J., Ritter M.A. In vivo selection of sFv from phage display libraries. J Immunol Methods 2000, 239:137-151.
    • (2000) J Immunol Methods , vol.239 , pp. 137-151
    • Johns, M.1    George, A.J.2    Ritter, M.A.3
  • 49
    • 79953686481 scopus 로고    scopus 로고
    • Identification of targeting peptides for ischemic myocardium by in vivo phage display
    • Kanki S., Jaalouk D.E., Lee S., Yu A.Y., Gannon J., Lee R.T. Identification of targeting peptides for ischemic myocardium by in vivo phage display. J Mol Cell Cardiol 2011, 50:841-848.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 841-848
    • Kanki, S.1    Jaalouk, D.E.2    Lee, S.3    Yu, A.Y.4    Gannon, J.5    Lee, R.T.6
  • 50
    • 33746871822 scopus 로고    scopus 로고
    • In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging
    • Kelly K.A., Nahrendorf M., Yu A.M., Reynolds F., Weissleder R. In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging. Mol Imaging Biol 2006, 8:201-207.
    • (2006) Mol Imaging Biol , vol.8 , pp. 201-207
    • Kelly, K.A.1    Nahrendorf, M.2    Yu, A.M.3    Reynolds, F.4    Weissleder, R.5
  • 51
    • 77951154576 scopus 로고    scopus 로고
    • Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight
    • Kim D.H., Woods S.C., Seeley R.J. Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight. Diabetes 2010, 59:907-915.
    • (2010) Diabetes , vol.59 , pp. 907-915
    • Kim, D.H.1    Woods, S.C.2    Seeley, R.J.3
  • 52
    • 78049468477 scopus 로고    scopus 로고
    • A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases
    • Kimball K.J., Preuss M.A., Barnes M.N., Wang M., Siegal G.P., Wan W., et al. A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases. Clin Cancer Res 2010, 16:5277-5287.
    • (2010) Clin Cancer Res , vol.16 , pp. 5277-5287
    • Kimball, K.J.1    Preuss, M.A.2    Barnes, M.N.3    Wang, M.4    Siegal, G.P.5    Wan, W.6
  • 53
    • 84861557846 scopus 로고    scopus 로고
    • CLT1 targets angiogenic endothelium through CLIC1 and fibronectin
    • Knowles L.M., Malik G., Hood B.L., Conrads T.P., Pilch J. CLT1 targets angiogenic endothelium through CLIC1 and fibronectin. Angiogenesis 2012, 15:115-129.
    • (2012) Angiogenesis , vol.15 , pp. 115-129
    • Knowles, L.M.1    Malik, G.2    Hood, B.L.3    Conrads, T.P.4    Pilch, J.5
  • 54
    • 2942703809 scopus 로고    scopus 로고
    • Reversal of obesity by targeted ablation of adipose tissue
    • Kolonin M.G., Saha P.K., Chan L., Pasqualini R., Arap W. Reversal of obesity by targeted ablation of adipose tissue. Nat Med 2004, 10:625-632.
    • (2004) Nat Med , vol.10 , pp. 625-632
    • Kolonin, M.G.1    Saha, P.K.2    Chan, L.3    Pasqualini, R.4    Arap, W.5
  • 55
    • 33845600732 scopus 로고    scopus 로고
    • Synchronous selection of homing peptides for multiple tissues by in vivo phage display
    • [-+]
    • Kolonin M.G., Sun J., Do K.A., Vidal C.I., Ji Y., Baggerly K.A., et al. Synchronous selection of homing peptides for multiple tissues by in vivo phage display. FASEB J 2006, 20:979. [-+].
    • (2006) FASEB J , vol.20 , pp. 979
    • Kolonin, M.G.1    Sun, J.2    Do, K.A.3    Vidal, C.I.4    Ji, Y.5    Baggerly, K.A.6
  • 56
    • 33747890567 scopus 로고    scopus 로고
    • Selection of tumor-binding ligands in cancer patients with phage display libraries
    • Krag D.N., Shukla G.S., Shen G.P., Pero S., Ashikaga T., Fuller S., et al. Selection of tumor-binding ligands in cancer patients with phage display libraries. Cancer Res 2006, 66:7724-7733.
    • (2006) Cancer Res , vol.66 , pp. 7724-7733
    • Krag, D.N.1    Shukla, G.S.2    Shen, G.P.3    Pero, S.4    Ashikaga, T.5    Fuller, S.6
  • 57
    • 33645466758 scopus 로고    scopus 로고
    • The use of phage-displayed peptide libraries to develop tumor-targeting drugs
    • Krumpe L.R., Mori T. The use of phage-displayed peptide libraries to develop tumor-targeting drugs. Int J Pept Res Ther 2006, 12:79-91.
    • (2006) Int J Pept Res Ther , vol.12 , pp. 79-91
    • Krumpe, L.R.1    Mori, T.2
  • 58
    • 0036063778 scopus 로고    scopus 로고
    • A tumor-homing peptide with a targeting specificity related to lymphatic vessels
    • Laakkonen P., Porkka K., Hoffman J.A., Ruoslahti E. A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat Med 2002, 8:751-755.
    • (2002) Nat Med , vol.8 , pp. 751-755
    • Laakkonen, P.1    Porkka, K.2    Hoffman, J.A.3    Ruoslahti, E.4
  • 61
    • 2942560767 scopus 로고    scopus 로고
    • Phage display-derived peptides as a therapeutic alternatives to antibodies
    • Ladner R.C., Sato A.K., Gorzelany J., de Souza M. Phage display-derived peptides as a therapeutic alternatives to antibodies. Drug Discov Today 2004, 9:525-529.
    • (2004) Drug Discov Today , vol.9 , pp. 525-529
    • Ladner, R.C.1    Sato, A.K.2    Gorzelany, J.3    de Souza, M.4
  • 64
    • 84887996477 scopus 로고    scopus 로고
    • Identification of homing peptides specific for human synovium by in vivo phage display selection
    • Lee L., Buckley C., Blades M., Panayi G., George A.J., Pitzalis C. Identification of homing peptides specific for human synovium by in vivo phage display selection. Arthritis Res Ther 2003, 5:103.
    • (2003) Arthritis Res Ther , vol.5 , pp. 103
    • Lee, L.1    Buckley, C.2    Blades, M.3    Panayi, G.4    George, A.J.5    Pitzalis, C.6
  • 65
    • 78049482695 scopus 로고    scopus 로고
    • Identification of a peptide sequence targeting mammary vasculature via RPLPO during lactation
    • Lee N.K., Kim M.K., Choi J.H., Kim E.B., Lee H.G., Kang S.K., et al. Identification of a peptide sequence targeting mammary vasculature via RPLPO during lactation. Peptides 2010, 31:2247-2254.
    • (2010) Peptides , vol.31 , pp. 2247-2254
    • Lee, N.K.1    Kim, M.K.2    Choi, J.H.3    Kim, E.B.4    Lee, H.G.5    Kang, S.K.6
  • 66
    • 80054709318 scopus 로고    scopus 로고
    • Identification of a novel peptide ligand targeting visceral adipose tissue via transdermal route by in vivo phage display
    • Lee N.K., Kim H.S., Kim K.H., Kim E.B., Cho C.S., Kang S.K., et al. Identification of a novel peptide ligand targeting visceral adipose tissue via transdermal route by in vivo phage display. J Drug Target 2011, 19:805-813.
    • (2011) J Drug Target , vol.19 , pp. 805-813
    • Lee, N.K.1    Kim, H.S.2    Kim, K.H.3    Kim, E.B.4    Cho, C.S.5    Kang, S.K.6
  • 67
    • 84862770544 scopus 로고    scopus 로고
    • Identification of peptide sequences that target to the brain using in vivo phage display
    • Li J.W., Zhang Q.Z., Pang Z.Q., Wang Y.C., Liu Q.F., Guo L.R., et al. Identification of peptide sequences that target to the brain using in vivo phage display. Amino Acids 2012, 42:2373-2381.
    • (2012) Amino Acids , vol.42 , pp. 2373-2381
    • Li, J.W.1    Zhang, Q.Z.2    Pang, Z.Q.3    Wang, Y.C.4    Liu, Q.F.5    Guo, L.R.6
  • 68
    • 77953357460 scopus 로고    scopus 로고
    • Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma
    • Loi M., Marchio S., Becherini P., Di Paolo D., Soster M., Curnis F., et al. Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma. J Control Release 2010, 145:66-73.
    • (2010) J Control Release , vol.145 , pp. 66-73
    • Loi, M.1    Marchio, S.2    Becherini, P.3    Di Paolo, D.4    Soster, M.5    Curnis, F.6
  • 69
    • 84863007720 scopus 로고    scopus 로고
    • Phase II study of NGR-hTNF in combination with doxorubicin in relapsed ovarian cancer patients
    • Lorusso D., Scambia G., Amadio G., di Legge A., Pietragalla A., De Vincenzo R., et al. Phase II study of NGR-hTNF in combination with doxorubicin in relapsed ovarian cancer patients. Br J Cancer 2012, 107:37-42.
    • (2012) Br J Cancer , vol.107 , pp. 37-42
    • Lorusso, D.1    Scambia, G.2    Amadio, G.3    di Legge, A.4    Pietragalla, A.5    De Vincenzo, R.6
  • 70
    • 34547952070 scopus 로고    scopus 로고
    • In vivo selection and validation of liver-specific ligands using a new t7 phage peptide display system
    • Ludtke J.J., Sololoff A.V., Wong S.C., Zhang G., Wolff J.A. In vivo selection and validation of liver-specific ligands using a new t7 phage peptide display system. Drug Deliv 2007, 14:357-369.
    • (2007) Drug Deliv , vol.14 , pp. 357-369
    • Ludtke, J.J.1    Sololoff, A.V.2    Wong, S.C.3    Zhang, G.4    Wolff, J.A.5
  • 71
    • 70349308251 scopus 로고    scopus 로고
    • Peptide-mediated targeting of hepatocytes via low density lipoprotein receptor-related protein (LRP)
    • Ludtke J.J., Sokoloff A.V., Wong S., Zhang G.F., Strickland D.K., Wolff J.A. Peptide-mediated targeting of hepatocytes via low density lipoprotein receptor-related protein (LRP). Drug Deliv 2009, 16:268-273.
    • (2009) Drug Deliv , vol.16 , pp. 268-273
    • Ludtke, J.J.1    Sokoloff, A.V.2    Wong, S.3    Zhang, G.F.4    Strickland, D.K.5    Wolff, J.A.6
  • 72
    • 79953329168 scopus 로고    scopus 로고
    • Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies
    • Mammoliti S., Andretta V., Bennicelli E., Caprioni F., Comandini D., Fornarini G., et al. Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies. Ann Oncol 2011, 22:973-978.
    • (2011) Ann Oncol , vol.22 , pp. 973-978
    • Mammoliti, S.1    Andretta, V.2    Bennicelli, E.3    Caprioni, F.4    Comandini, D.5    Fornarini, G.6
  • 73
    • 84873077884 scopus 로고    scopus 로고
    • Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer
    • Manegold C., Vansteenkiste J., Cardenal F., Schuette W., Woll P.J., Ulsperger E., et al. Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer. Invest New Drugs 2012, 31:175-182.
    • (2012) Invest New Drugs , vol.31 , pp. 175-182
    • Manegold, C.1    Vansteenkiste, J.2    Cardenal, F.3    Schuette, W.4    Woll, P.J.5    Ulsperger, E.6
  • 74
    • 4143098147 scopus 로고    scopus 로고
    • In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo
    • McGuire M.J., Samli K.N., Johnston S.A., Brown K.C. In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo. J Mol Biol 2004, 342:171-182.
    • (2004) J Mol Biol , vol.342 , pp. 171-182
    • McGuire, M.J.1    Samli, K.N.2    Johnston, S.A.3    Brown, K.C.4
  • 75
    • 33746903085 scopus 로고    scopus 로고
    • Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting
    • Meyer A., Auemheimer J., Modlinger A., Kessler H. Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting. Curr Pharm Des 2006, 12:2723-2747.
    • (2006) Curr Pharm Des , vol.12 , pp. 2723-2747
    • Meyer, A.1    Auemheimer, J.2    Modlinger, A.3    Kessler, H.4
  • 78
    • 3042825003 scopus 로고    scopus 로고
    • Cancer-specific ligands identified from screening of peptide-display libraries
    • Mori T. Cancer-specific ligands identified from screening of peptide-display libraries. Curr Pharm Des 2004, 10:2335-2343.
    • (2004) Curr Pharm Des , vol.10 , pp. 2335-2343
    • Mori, T.1
  • 79
    • 33749042410 scopus 로고    scopus 로고
    • In vivo selection of phage for the optical Imaging of PC-3 human prostate carcinoma in mice
    • Newton J.R., Kelly K.A., Mahmood U., Weissleder R., Deutscher S.L. In vivo selection of phage for the optical Imaging of PC-3 human prostate carcinoma in mice. Neoplasia 2006, 8:772-780.
    • (2006) Neoplasia , vol.8 , pp. 772-780
    • Newton, J.R.1    Kelly, K.A.2    Mahmood, U.3    Weissleder, R.4    Deutscher, S.L.5
  • 80
    • 67349168759 scopus 로고    scopus 로고
    • Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature
    • Nicol C.G., Denby L., Lopez-Franco O., Masson R., Halliday C.A., Nicklin S.A., et al. Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature. FEBS Lett 2009, 583:2100-2107.
    • (2009) FEBS Lett , vol.583 , pp. 2100-2107
    • Nicol, C.G.1    Denby, L.2    Lopez-Franco, O.3    Masson, R.4    Halliday, C.A.5    Nicklin, S.A.6
  • 81
    • 0034846826 scopus 로고    scopus 로고
    • Construction of high-complexity combinatorial phage display peptide libraries
    • Noren K.A., Noren C.J. Construction of high-complexity combinatorial phage display peptide libraries. Methods 2001, 23:169-178.
    • (2001) Methods , vol.23 , pp. 169-178
    • Noren, K.A.1    Noren, C.J.2
  • 82
    • 8644283752 scopus 로고    scopus 로고
    • A specific heptapeptide from a phage display peptide library homes to bone marrow and binds to primitive hematopoietic stem cells
    • Nowakowski G.S., Dooner M.S., Valinski H.M., Mihaliak A.M., Quesenberry P.J., Becker P.S. A specific heptapeptide from a phage display peptide library homes to bone marrow and binds to primitive hematopoietic stem cells. Stem Cells 2004, 22:1030-1038.
    • (2004) Stem Cells , vol.22 , pp. 1030-1038
    • Nowakowski, G.S.1    Dooner, M.S.2    Valinski, H.M.3    Mihaliak, A.M.4    Quesenberry, P.J.5    Becker, P.S.6
  • 83
    • 0036132651 scopus 로고    scopus 로고
    • Selection of high affinity p-azophenyarsonate Fabs from heavy-chain CDR2 insertion libraries
    • Parhami-Seren B., Viswanathan M., Margolies M.N. Selection of high affinity p-azophenyarsonate Fabs from heavy-chain CDR2 insertion libraries. J Immunol Methods 2002, 259:43-53.
    • (2002) J Immunol Methods , vol.259 , pp. 43-53
    • Parhami-Seren, B.1    Viswanathan, M.2    Margolies, M.N.3
  • 84
    • 0032982234 scopus 로고    scopus 로고
    • Vascular targeting with phage peptide libraries
    • Pasqualini R. Vascular targeting with phage peptide libraries. Q J Nucl Med 1999, 43:159-162.
    • (1999) Q J Nucl Med , vol.43 , pp. 159-162
    • Pasqualini, R.1
  • 85
    • 0029932458 scopus 로고    scopus 로고
    • Organ targeting in vivo using phage display peptide libraries
    • Pasqualini R., Ruoslahti E. Organ targeting in vivo using phage display peptide libraries. Nature 1996, 380:364-366.
    • (1996) Nature , vol.380 , pp. 364-366
    • Pasqualini, R.1    Ruoslahti, E.2
  • 86
    • 0030940283 scopus 로고    scopus 로고
    • Alpha v integrins as receptors for tumor targeting by circulating ligands
    • Pasqualini R., Koivunen E., Ruoslahti E. Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol 1997, 15:542-546.
    • (1997) Nat Biotechnol , vol.15 , pp. 542-546
    • Pasqualini, R.1    Koivunen, E.2    Ruoslahti, E.3
  • 87
    • 0033950895 scopus 로고    scopus 로고
    • Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
    • Pasqualini R., Koivunen E., Kain R., Lahdenranta J., Sakamoto M., Stryhn A., et al. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res 2000, 60:722-727.
    • (2000) Cancer Res , vol.60 , pp. 722-727
    • Pasqualini, R.1    Koivunen, E.2    Kain, R.3    Lahdenranta, J.4    Sakamoto, M.5    Stryhn, A.6
  • 88
    • 0021271957 scopus 로고
    • Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule
    • Pierschbacher M.D., Ruoslahti E. Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature 1984, 309:30-33.
    • (1984) Nature , vol.309 , pp. 30-33
    • Pierschbacher, M.D.1    Ruoslahti, E.2
  • 89
  • 90
    • 0034285785 scopus 로고    scopus 로고
    • Phage display of antibody fragments
    • Pini A., Bracci L. Phage display of antibody fragments. Curr Protein Pept Sci 2000, 1:155-169.
    • (2000) Curr Protein Pept Sci , vol.1 , pp. 155-169
    • Pini, A.1    Bracci, L.2
  • 91
    • 0344494515 scopus 로고    scopus 로고
    • Tumor vasculature address book: Identification of stage-specific tumor vessel zip codes by phage display
    • Rafii S., Avecilla S.T., Jin D.K. Tumor vasculature address book: Identification of stage-specific tumor vessel zip codes by phage display. Cancer Cell 2003, 4:331-333.
    • (2003) Cancer Cell , vol.4 , pp. 331-333
    • Rafii, S.1    Avecilla, S.T.2    Jin, D.K.3
  • 92
    • 0033597209 scopus 로고    scopus 로고
    • Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display
    • Rajotte D., Ruoslahti E. Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display. J Biol Chem 1999, 274:11593-11598.
    • (1999) J Biol Chem , vol.274 , pp. 11593-11598
    • Rajotte, D.1    Ruoslahti, E.2
  • 94
    • 51449124031 scopus 로고    scopus 로고
    • Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme
    • Reardon D.A., Nabors L.B., Stupp R., Mikkelsen T. Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme. Expert Opin Investig Drugs 2008, 17:1225-1235.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 1225-1235
    • Reardon, D.A.1    Nabors, L.B.2    Stupp, R.3    Mikkelsen, T.4
  • 95
    • 33846010537 scopus 로고    scopus 로고
    • Identification of human scFvs targeting atherosclerotic lesions: selection by single round in vivo phage display
    • Robert R., Jacobin-Valat M.J., Daret D., Miraux S., Nurden A.T., Franconi J.M., et al. Identification of human scFvs targeting atherosclerotic lesions: selection by single round in vivo phage display. J Biol Chem 2006, 281:40135-40143.
    • (2006) J Biol Chem , vol.281 , pp. 40135-40143
    • Robert, R.1    Jacobin-Valat, M.J.2    Daret, D.3    Miraux, S.4    Nurden, A.T.5    Franconi, J.M.6
  • 96
    • 0023637601 scopus 로고
    • New perspectives in cell adhesion: RGD and integrins
    • Ruoslahti E., Pierschbacher M.D. New perspectives in cell adhesion: RGD and integrins. Science 1987, 238:491-497.
    • (1987) Science , vol.238 , pp. 491-497
    • Ruoslahti, E.1    Pierschbacher, M.D.2
  • 97
    • 0032912835 scopus 로고    scopus 로고
    • Elucidation of muscle-binding peptides by phage display screening
    • Samoylova T.I., Smith B.F. Elucidation of muscle-binding peptides by phage display screening. Muscle Nerve 1999, 22:460-466.
    • (1999) Muscle Nerve , vol.22 , pp. 460-466
    • Samoylova, T.I.1    Smith, B.F.2
  • 98
    • 77956438555 scopus 로고    scopus 로고
    • Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma
    • Santoro A., Pressiani T., Citterio G., Rossoni G., Donadoni G., Pozzi F., et al. Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma. Br J Cancer 2010, 103:837-844.
    • (2010) Br J Cancer , vol.103 , pp. 837-844
    • Santoro, A.1    Pressiani, T.2    Citterio, G.3    Rossoni, G.4    Donadoni, G.5    Pozzi, F.6
  • 99
    • 77957197962 scopus 로고    scopus 로고
    • Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy
    • Santoro A., Rimassa L., Sobrero A.F., Citterio G., Sclafani F., Carnaghi C., et al. Phase II study of NGR-hTNF, a selective vascular targeting agent, in patients with metastatic colorectal cancer after failure of standard therapy. Eur J Cancer 2010, 46:2746-2752.
    • (2010) Eur J Cancer , vol.46 , pp. 2746-2752
    • Santoro, A.1    Rimassa, L.2    Sobrero, A.F.3    Citterio, G.4    Sclafani, F.5    Carnaghi, C.6
  • 100
    • 84867830537 scopus 로고    scopus 로고
    • Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results
    • Scaringi C., Minniti G., Caporello P., Enrici R.M. Integrin inhibitor cilengitide for the treatment of glioblastoma: a brief overview of current clinical results. Anticancer Res 2012, 32:4213-4223.
    • (2012) Anticancer Res , vol.32 , pp. 4213-4223
    • Scaringi, C.1    Minniti, G.2    Caporello, P.3    Enrici, R.M.4
  • 101
    • 77956681923 scopus 로고    scopus 로고
    • Identification of a novel muscle targeting peptide in mdx mice
    • Seow Y., Yin H., Wood M.J. Identification of a novel muscle targeting peptide in mdx mice. Peptides 2010, 31:1873-1877.
    • (2010) Peptides , vol.31 , pp. 1873-1877
    • Seow, Y.1    Yin, H.2    Wood, M.J.3
  • 102
    • 0021818675 scopus 로고
    • Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface
    • Smith G.P. Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 1985, 228:1315-1317.
    • (1985) Science , vol.228 , pp. 1315-1317
    • Smith, G.P.1
  • 103
    • 3142617356 scopus 로고    scopus 로고
    • In utero detection of T7 phage after systemic administration to pregnant mice
    • Srivastava A.S., Chauhan D.P., Carrier E. In utero detection of T7 phage after systemic administration to pregnant mice. Biotechniques 2004, 37:81-83.
    • (2004) Biotechniques , vol.37 , pp. 81-83
    • Srivastava, A.S.1    Chauhan, D.P.2    Carrier, E.3
  • 104
    • 0344628610 scopus 로고    scopus 로고
    • Immunological factors that affect the in vivo fate of T7 phage in the mouse
    • Srivastava A.S., Kaido T., Carrier E. Immunological factors that affect the in vivo fate of T7 phage in the mouse. J Virol Methods 2004, 115:99-104.
    • (2004) J Virol Methods , vol.115 , pp. 99-104
    • Srivastava, A.S.1    Kaido, T.2    Carrier, E.3
  • 106
    • 77954924659 scopus 로고    scopus 로고
    • Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma
    • Stupp R., Hegi M.E., Neyns B., Goldbrunner R., Schlegel U., Clement P.M., et al. Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol 2010, 28:2712-2718.
    • (2010) J Clin Oncol , vol.28 , pp. 2712-2718
    • Stupp, R.1    Hegi, M.E.2    Neyns, B.3    Goldbrunner, R.4    Schlegel, U.5    Clement, P.M.6
  • 108
    • 0035138689 scopus 로고    scopus 로고
    • A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency
    • Suzuki K., Fueyo J., Krasnykh V., Reynolds P.N., Curiel D.T., Alemany R. A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin Cancer Res 2001, 7:120-126.
    • (2001) Clin Cancer Res , vol.7 , pp. 120-126
    • Suzuki, K.1    Fueyo, J.2    Krasnykh, V.3    Reynolds, P.N.4    Curiel, D.T.5    Alemany, R.6
  • 109
    • 74749090621 scopus 로고    scopus 로고
    • Phage library-screening: a powerful approach for generation of targeting-agents specific for normal pancreatic islet-cells and islet-cell carcinoma in vivo
    • Ueberberg S., Schneider S. Phage library-screening: a powerful approach for generation of targeting-agents specific for normal pancreatic islet-cells and islet-cell carcinoma in vivo. Regul Pept 2010, 160:1-8.
    • (2010) Regul Pept , vol.160 , pp. 1-8
    • Ueberberg, S.1    Schneider, S.2
  • 110
    • 70349640797 scopus 로고    scopus 로고
    • Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo
    • Ueberberg S., Meier J.J., Waengler C., Schechinger W., Dietrich J.W., Tannapfel A., et al. Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo. Diabetes 2009, 58:2324-2334.
    • (2009) Diabetes , vol.58 , pp. 2324-2334
    • Ueberberg, S.1    Meier, J.J.2    Waengler, C.3    Schechinger, W.4    Dietrich, J.W.5    Tannapfel, A.6
  • 111
    • 79959574297 scopus 로고    scopus 로고
    • Protection from diabetes development by single-chain antibody-mediated delivery of a NF-kappaB inhibitor specifically to beta-cells in vivo
    • Ueberberg S., Deutschbein T., Klein H.H., Dietrich J.W., Akinturk S., Prochnow N., et al. Protection from diabetes development by single-chain antibody-mediated delivery of a NF-kappaB inhibitor specifically to beta-cells in vivo. Am J Physiol Endocrinol Metab 2011, 301:E83-E90.
    • (2011) Am J Physiol Endocrinol Metab , vol.301
    • Ueberberg, S.1    Deutschbein, T.2    Klein, H.H.3    Dietrich, J.W.4    Akinturk, S.5    Prochnow, N.6
  • 113
    • 79957671402 scopus 로고    scopus 로고
    • Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part
    • Vermorken J.B., Guigay J., Mesia R., Trigo J.M., Keilholz U., Kerber A., et al. Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part. Br J Cancer 2011, 104:1691-1696.
    • (2011) Br J Cancer , vol.104 , pp. 1691-1696
    • Vermorken, J.B.1    Guigay, J.2    Mesia, R.3    Trigo, J.M.4    Keilholz, U.5    Kerber, A.6
  • 114
    • 58149507967 scopus 로고    scopus 로고
    • Identification of nose-to-brain homing peptide through phage display
    • Wan X.M., Chen Y.P., Xu W.R., Yang W.J., Wen L.P. Identification of nose-to-brain homing peptide through phage display. Peptides 2009, 30:343-350.
    • (2009) Peptides , vol.30 , pp. 343-350
    • Wan, X.M.1    Chen, Y.P.2    Xu, W.R.3    Yang, W.J.4    Wen, L.P.5
  • 115
    • 0042525959 scopus 로고    scopus 로고
    • Mapping alveolar binding sites in vivo using phage peptide libraries
    • Wu M., Pasula R., Smith P.A., Martin W.J. Mapping alveolar binding sites in vivo using phage peptide libraries. Gene Ther 2003, 10:1429-1436.
    • (2003) Gene Ther , vol.10 , pp. 1429-1436
    • Wu, M.1    Pasula, R.2    Smith, P.A.3    Martin, W.J.4
  • 116
    • 84858722973 scopus 로고    scopus 로고
    • A radiolabeled nonapeptide probe targeting PC-3 cells and bone metastases of prostate cancer in mice
    • Wu Q.H., Xu J.L., Lu L., Yang Z.X., Tong G.S., Gao H.L., et al. A radiolabeled nonapeptide probe targeting PC-3 cells and bone metastases of prostate cancer in mice. Contrast Media Mol Imaging 2012, 7:223-230.
    • (2012) Contrast Media Mol Imaging , vol.7 , pp. 223-230
    • Wu, Q.H.1    Xu, J.L.2    Lu, L.3    Yang, Z.X.4    Tong, G.S.5    Gao, H.L.6
  • 117
    • 33646876609 scopus 로고    scopus 로고
    • Expression, refolding, and characterization of GFE peptide-fused human interferon-alpha2a in Escherichia coli
    • Yan Z., Lu L., Shi J., Bao C., Han W., Wu Y., et al. Expression, refolding, and characterization of GFE peptide-fused human interferon-alpha2a in Escherichia coli. Appl Biochem Biotechnol 2006, 133:149-162.
    • (2006) Appl Biochem Biotechnol , vol.133 , pp. 149-162
    • Yan, Z.1    Lu, L.2    Shi, J.3    Bao, C.4    Han, W.5    Wu, Y.6
  • 118
    • 58149383693 scopus 로고    scopus 로고
    • Mouse thymus targeted peptide isolated by in vivo phage display can inhibit bioactivity of thymus output in vivo
    • Yang Y., Zizheng W., Tongxin D. Mouse thymus targeted peptide isolated by in vivo phage display can inhibit bioactivity of thymus output in vivo. J Biomol Screen 2008, 13:968-974.
    • (2008) J Biomol Screen , vol.13 , pp. 968-974
    • Yang, Y.1    Zizheng, W.2    Tongxin, D.3
  • 119
    • 79953315453 scopus 로고    scopus 로고
    • Phage display random peptide library for screening the peptides that specifically bind to hepatocellular carcinoma cells
    • Yang P., He J.T., Wang J.W., Hu Y., Yu L., Jin X., et al. Phage display random peptide library for screening the peptides that specifically bind to hepatocellular carcinoma cells. Nan Fang Yi Ke Da Xue Xue Bao 2009, 29:1806-1808.
    • (2009) Nan Fang Yi Ke Da Xue Xue Bao , vol.29 , pp. 1806-1808
    • Yang, P.1    He, J.T.2    Wang, J.W.3    Hu, Y.4    Yu, L.5    Jin, X.6
  • 120
    • 13244284964 scopus 로고    scopus 로고
    • Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection
    • Yao V.J., Ozawa M.G., Trepel M., Arap W., McDonald D.M., Pasqualini R. Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection. Am J Pathol 2005, 166:625-636.
    • (2005) Am J Pathol , vol.166 , pp. 625-636
    • Yao, V.J.1    Ozawa, M.G.2    Trepel, M.3    Arap, W.4    McDonald, D.M.5    Pasqualini, R.6
  • 121
    • 69249213448 scopus 로고    scopus 로고
    • A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery
    • Yu C.Y., Yuan Z., Cao Z., Wang B., Qiao C., Li J., et al. A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery. Gene Ther 2009, 16:953-962.
    • (2009) Gene Ther , vol.16 , pp. 953-962
    • Yu, C.Y.1    Yuan, Z.2    Cao, Z.3    Wang, B.4    Qiao, C.5    Li, J.6
  • 122
    • 24944535233 scopus 로고    scopus 로고
    • Molecular profiling of heart endothelial cells
    • Zhang L.L., Hoffman J.A., Ruoslahti E. Molecular profiling of heart endothelial cells. Circulation 2005, 112:1601-1611.
    • (2005) Circulation , vol.112 , pp. 1601-1611
    • Zhang, L.L.1    Hoffman, J.A.2    Ruoslahti, E.3
  • 123
    • 78049499436 scopus 로고    scopus 로고
    • Transmembrane delivery and biological effect of human growth hormone via a phage displayed peptide in vivo and in vitro
    • Zhang T., Qu H.Y., Li X.L., Zhao B.Q., Zhou J.P., Li Q.A., et al. Transmembrane delivery and biological effect of human growth hormone via a phage displayed peptide in vivo and in vitro. J Pharm Sci 2010, 99:4880-4891.
    • (2010) J Pharm Sci , vol.99 , pp. 4880-4891
    • Zhang, T.1    Qu, H.Y.2    Li, X.L.3    Zhao, B.Q.4    Zhou, J.P.5    Li, Q.A.6
  • 125
    • 1642475187 scopus 로고    scopus 로고
    • Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer
    • Zurita A.J., Troncoso P., Cardo-Vila M., Logothetis C.J., Pasqualini R., Arap W. Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer. Cancer Res 2004, 64:435-439.
    • (2004) Cancer Res , vol.64 , pp. 435-439
    • Zurita, A.J.1    Troncoso, P.2    Cardo-Vila, M.3    Logothetis, C.J.4    Pasqualini, R.5    Arap, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.