By-passing large screening experiments using sequencing as a tool to identify scFv fragments targeting atherosclerotic lesions in a novel in vivo phage display selection

International Journal of Molecular Sciences

Volumn 13, Issue 6, 2012, Pages 6902-6923

  Deramchia, Kamel ^a,b   Jacobin Valat, Marie Josee ^a,b   Laroche Traineau, Jeanny ^a,b   Bonetto, Stephane ^a,b   Sanchez, Stephane ^a   Dos Santos, Pierre ^b   Massot, Philippe ^a   Franconi, Jean Michel ^a   Martineau, Pierre ^c   Clofent Sanchez, Gisele ^a,b  

^a CNRS University Bordeaux Segalen   (France)

^b Bordeaux Segalen University   (France)

^c INSTITUT DE RECHERCHE EN CANCÉROLOGIE DE MONTPELLIER   (France)

Author keywords

Atherosclerosis; Biopanning; Human antibody; In vivo phage display; Semi synthetic phage display library; Single chain variable fragment (scFv)

Indexed keywords

SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; PEPTIDE LIBRARY;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY LIBRARY; AORTA INTIMA; ARTICLE; ATHEROSCLEROSIS; BINDING ASSAY; BIOPANNING; CLONE; CONTROLLED STUDY; DISEASE MODEL; ENDOTHELIUM CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHAGE DISPLAY; SEQUENCE ANALYSIS; THORACIC AORTA; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; FOAM CELL; HUMAN; INFLAMMATION; INTIMA; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATHOPHYSIOLOGY; PEPTIDE LIBRARY; RABBIT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; AORTA, ABDOMINAL; ATHEROSCLEROSIS; FOAM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MAGNETIC RESONANCE IMAGING; MALE; MASS SPECTROMETRY; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; SINGLE-CHAIN ANTIBODIES; TUNICA INTIMA;

EID: 84862489781     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13066902     Document Type: Article

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