Phage library-screening: A powerful approach for generation of targeting-agents specific for normal pancreatic islet-cells and islet-cell carcinoma in vivo

Regulatory Peptides

Volumn 160, Issue 1-3, 2010, Pages 1-8

  Ueberberg, S ^a   Schneider, S ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Alpha cell; Beta cell; Biopanning; Diabetes; Islet vasculature; Islet cell carcinoma; Pancreatic islet; Peptides; Phage display; Pre malignant islet; Single chain antibody; Targeting agents; Vascular endothelium

Indexed keywords

ANTIBODY; ARGINYLALANYLSERYLGLUTAMINYLSERYLISOLEUCYLSERYLSERYLTYROSYLLEUCYLASPARAGINE; CYSTEINYLARGINYLGLYCYLARGINYLARGINYLSERYLTHREONINE; CYSTEINYLARGINYLSERYLARGINYLLYSYLGLYCINE; CYSTEINYLHISTIDINYLVALYLLEUCYLTRYPTOPHYLSERYLTHREONYLARGINYLCYSTEINE; CYSTEINYLLYSYLALANYLALANYLLYSYLASPARAGINYLLYSINE; CYSTEINYLVALYLSERYLASPARAGINYLPROLYLARGINYLTRYPTOPHYLLYSYLCYSTEINE; EPHRIN A2; EPHRIN A4; GLUTAMINYLGLUTAMINYLLYSYLTRYPTOPHYLASPARTYLPROLYLPROLYLARGINYLTHREONINE; GLYCYLPHENYLALANYLTHREONYLPHENYLALANYLSERYLSERYLTYROSYLALANYLMETHIONYLSERINE; LEUCYLSERYLGLYCYLTHREONYLPROPYLGLUTAMYLARGINYLSERYLGLYCYLGLUTAMINYLALANYLVALYLLYSYLVALYLLYSYLLEUCYLLYSYLALANYLISOLEUCYLPROLINE; LIGAND; LYSYLALANYLSERYLARGINYLLEUCYLGLUTAMINYLSERINE; LYSYLTHREONYLSERYLTYROSYLARGINYLPHENYLALANINE; PEPTIDE; PEPTIDE LIBRARY; PLATELET DERIVED GROWTH FACTOR B; POLYPEPTIDE; SERYLISOLEUCYLTHREONYLALANYLGLUTAMYLARGINYLTHREONYLHISTIDINYLTHREONYLTRYPTOPHYLTYROSYLALANYLASPARTYLSERYLVALYLLYSYLGLYCYLARGINYLPHENYLALANINE; SINGLE CHAIN ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; WNT2 PROTEIN;

ANTIBODY ISOLATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; ORGAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PANCREAS ISLET CELL CARCINOMA; PANCREAS ISLET CELL TUMOR; PHAGE DISPLAY; PRECANCER; PRIORITY JOURNAL; REVIEW; RODENT; TUMOR; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIBODIES; BACTERIOPHAGES; BLOOD VESSELS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; HUMANS; ISLETS OF LANGERHANS; LIGANDS; PANCREATIC NEOPLASMS; PEPTIDE LIBRARY; PEPTIDES;

RATTUS; RODENTIA;

EID: 74749090621     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2009.11.017     Document Type: Review

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